DNA-PKCS shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemDNA-PKCS shRNA Plasmid (h)
CompanySanta Cruz Biotechnology, Inc.
Price $592.00Supplier Page View Company Product Page
Catalog Numbersc-35200-SH
RNA TypeshRNA Clones
Vector Type (Standardized)Lentiviral
TypeshRNA Plasmid
Specieshuman
NCBI Full Gene Nameprotein kinase, DNA-activated, catalytic subunit
NCBI Gene AliasesDNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, IMD26, XRCC7, p350
Quantity20 µg

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

(1) DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTROncotargetFebruary 18, 2020Zicari S, Sharma AL, Sahu G, Dubrovsky L, Sun L, Yue H, Jada T, Ochem A, Simon G, Bukrinsky M, et al.was purchased. Stock solutions were made in DMSO at 5 mM concentration. DNA-PKcs shRNA vectors (Cat # sc-35200-SH) were purchased from Santa Cruz Biotech. In some experiments, we also used the lentiviral vector pHR’Sin-Puro

(2) The crucial role of DNA-dependent protein kinase and myelin transcription factor 1-like protein in the miR-141 tumor suppressor networkCell cycle (Georgetown, Tex.)November 1, 2019Wang B, Li D, Yao Y, Heyns M, Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Bronson RT, Metz GAS, Kovalchuk O, et al.

(3) Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcriptionNucleic acids researchJuly 26, 2019Velichko AK, Petrova NV, Luzhin AV, Strelkova OS, Ovsyannikova N, Kireev II, Petrova NV, Razin SV, Kantidze OL.

(4) NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA RepairCell reportsFebruary 19, 2019Munnur D, Somers J, Skalka G, Weston R, Jukes-Jones R, Bhogadia M, Dominguez C, Cain K, Ahel I, Malewicz M.

(6) DHX9 regulates production of hepatitis B virus-derived circular RNA and viral protein levelsOncotargetApril 20, 2018Sekiba K, Otsuka M, Ohno M, Kishikawa T, Yamagami M, Suzuki T, Ishibashi R, Seimiya T, Tanaka E, Koike K.

(10) Distinct Roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the Transcriptional Regulation of MICA and PVR/CD155 ExpressionJournal of immunology (Baltimore, Md. : 1950)November 15, 2016Pignoloni B, Fionda C, Dell'Oste V, Luganini A, Cippitelli M, Zingoni A, Landolfo S, Gribaudo G, Santoni A, Cerboni C.

(11) Chk1 and DNA-PK mediate TPEN-induced DNA damage in a ROS dependent manner in human colon cancer cellsCancer biology & therapyNovember 1, 2016Rahal ON, Fatfat M, Hankache C, Osman B, Khalife H, Machaca K, Muhtasib HG.

(12) CD133 and DNA-PK regulate MDR1 via the PI3K- or Akt-NF-κB pathway in multidrug-resistant glioblastoma cells in vitroOncogeneJanuary 14, 2016Xi G, Hayes E, Lewis R, Ichi S, Mania-Farnell B, Shim K, Takao T, Allender E, Mayanil CS, Tomita T.

(13) DNA-PKcs interference sensitizes colorectal cancer cells to a mTOR kinase inhibitor WAY-600Biochemical and biophysical research communicationsOctober 23, 2015Wu L, Zhang J, Wu H, Han E.

(15) Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapyOncotargetJune 10, 2015Lamb R, Fiorillo M, Chadwick A, Ozsvari B, Reeves KJ, Smith DL, Clarke RB, Howell SJ, Cappello AR, Martinez-Outschoorn UE, et al.

(16) DNA-PKcs deficiency inhibits glioblastoma cell-derived angiogenesis after ionizing radiationJournal of cellular physiologyMay 1, 2015Liu Y, Zhang L, Liu Y, Sun C, Zhang H, Miao G, Di CX, Zhou X, Zhou R, Wang Z.

(18) DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4⁺ T-cell function without causing severe combined immunodeficiencyThe Journal of allergy and clinical immunologyFebruary 1, 2015Ghonim MA, Pyakurel K, Ju J, Rodriguez PC, Lammi MR, Davis C, Abughazleh MQ, Mansy MS, Naura AS, Boulares AH.

(20) DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasionCell cycle (Georgetown, Tex.)January 1, 2015Kotula E, Berthault N, Agrario C, Lienafa MC, Simon A, Dingli F, Loew D, Sibut V, Saule S, Dutreix M.

DNA-PKCS shRNA Plasmid (h)