SignalSilence ® BRCA1 siRNA I from Cell Signaling Technology

Product Specs
ItemSignalSilence ® BRCA1 siRNA I
CompanyCell Signaling Technology
Price $369.00 Inquire
Catalog Number12519S
ReactivityH
ApplicationssiRNA
TypesiRNA
Research AreaCell Cycle / Checkpoint Control
NCBI Gene AliasesBRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53
NCBI Full Gene NameBRCA1 DNA repair associated
TargetBRCA1
Quantity300 µl

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) GSK3B directs DNA repair choice and determines tumor response to PARP1 inhibition independent of BRCA1J Clin InvestNovember 17, 2025Heba S. Allam, Scarlett Acklin-Wehnert, Ratan Sadhukhan, Mousumi Patra, Fen Xiapolybrene (Sigma). For BRCA1 knock down, Signal Silence BRCA1 siRNA was purchased from Cell signaling, # 12519. 53BP1 knockout cells used in this study were generated using the CRISPR/Cas9 method (58). Two specific

(2) GSK3B directs DNA repair choice and determines tumor response to PARP1 inhibition independent of BRCA1Journal of Clinical InvestigationNovember 17, 2025Heba S. Allam, Scarlett Acklin-Wehnert, Ratan Sadhukhan, Mousumi Patra, Fen Xiapolybrene (Sigma). For BRCA1 knock down, Signal Silence BRCA1 siRNA was purchased from Cell signaling, # 12519. 53BP1 knockout cells used in this study were generated using the CRISPR/Cas9 method (58). Two specific

(3) The BRCA1 BRCT promotes antisense RNA production and double-stranded RNA formation to suppress ribosomal R-loopsProceedings of the National Academy of Sciences of the United States of AmericaDecember 13, 2022Chang CW, Singh AK, Li M, Guan L, Le N, Omabe K, Liang F, Liu Y.cells for 4 h before harvesting. BRCA2 siRNA (sc-29825) was purchased from Santa Cruz. BRCA1 siRNA (#12519S) was purchased from Cell Signaling. siRNA was transfected using Lipofectamine RNAiMax (Invitrogen) according

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