TrueGuide gRNA, custom, modified from Thermo Fisher Scientific

Description

Invitrogen TrueGuide Synthetic gRNAs are ready-to-use, synthetic gRNAs enabling researchers to truly harness the power of genome editing. TrueGuide Synthetic gRNAs both maximize and simplify the performance of genome editing experiments so researchers can create more relevant cellular models and make new discoveries

Product Specs
ItemTrueGuide gRNA, custom, modified
CompanyThermo Fisher Scientific
Price $445.00Supplier Page View Company Product Page
Catalog NumberA35514
Quantity3nmol
Research AreaCell Analysis, Drug Screening, CRISPR Knockout Kits, Libraries, Gene Editing Services, High Throughput Screening,Expression Analysis, CRISPR Products, Molecular Biology Applications
TypeGuide RNA
FormatSynthetic
Regulatory StatusFor Research Use Only. Not for use in diagnostic procedures

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Thermo Fisher Scientific

168 Third Avenue

Waltham, MA 02451

United States

Phone: 800-678-5599

Company Profile

Website: www.thermofisher.com

(1) Optimally engineered HLA/peptide-specific CAR-T cells outperform TCR-T cells to eradicate solid tumorsScience AdvancesJanuary 23, 2026Corinne E. Decker, Jacqueline Idun, Katja Mohrs, Thomas Craig Meagher, Iryna Petriv, Jonathon Golas, Robert Salzler, Timothy Helms, Dharani Ajithdoss, Suhasini Avvaru, et al.nucleofection (Lonza, V4SP-3096) with single guide RNAs (sgRNAs) to TCR α and β constant regions (Invitrogen, A35514) and Cas9 protein (A36499). T cells receiving CAR lentivirus were electroporated without sgRNAs or Cas9.

(2) Allele-specific CRISPR-Cas9 editing of dominant epidermolysis bullosa simplex in human epidermal stem cellsMolecular TherapyFebruary 7, 2024C. Cattaneo, E. Enzo, L. De Rosa, L. Sercia, F. Consiglio, M. Forcato, S. Bicciato, A. Paiardini, G. Basso, E. Tagliafico, et al.directly flanking an AGG PAM. It was modified to drive the maximum editing efficiency (Invitrogen, #A35514; Table S1) and was mixed in a 1.1:1 molar ratio with the Cas9 protein (Alt-R S.p. Cas9 Nuclease V3,

(3) Enhanced CRISPR/Cas9-mediated precise genome editing by improved design and delivery of gRNA, Cas9 nuclease, and donor DNAJournal of biotechnologyNovember 11, 2016Xiquan Liang, Jason Potter, Shantanu Kumar, Namritha Ravinder, Jonathan D Chesnut

(4) Improved delivery of Cas9 protein/gRNA complexes using lipofectamine CRISPRMAXBiotechnology lettersJune 1, 2016Xin Yu, Xiquan Liang, Huimin Xie, Shantanu Kumar, Namritha Ravinder, Jason Potter, Xavier de Mollerat du Jeu, Jonathan D Chesnut

(5) Rapid and highly efficient mammalian cell engineering via Cas9 protein transfectionJournal of biotechnologyAugust 20, 2015Xiquan Liang, Jason Potter, Shantanu Kumar, Yanfei Zou, Rene Quintanilla, Mahalakshmi Sridharan, Jason Carte, Wen Chen, Natasha Roark, Sridhar Ranganathan, Namritha Ravinder, Jonathan D Chesnut

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TrueGuide gRNA, custom, modified from Thermo Fisher Scientific

Description

Thermo Fisher Scientific

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TrueGuide gRNA, custom, modified from Thermo Fisher Scientific

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