Rapamycin from Santa Cruz Biotechnology, Inc.

Product Specs
ItemRapamycin
CompanySanta Cruz Biotechnology, Inc.
Price $62.00Supplier Page View Company Product Page
Catalog Numbersc-3504
Quantity1 mg
TypeBiochemical Reagents
Molecular Weight914.17

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Hierarchical interplay between H3K27ac and H3K4me3 in transcriptional regulationNature CommunicationsJune 22, 2026Chenwei Zhou, Chanjuan Dong, Weiye Zhao, Fu-Sen Liangcells were treated with 100 µM abscisic acid ABA (Glod Biotechnology #A-050-5), 20 nM Rap (Santa Cruz #sc-3504), or an equivalent volume of DMSO (negative control) and incubated for an additional 24 h. For large-scale

(2) TRIM22 functions as a scaffold protein for autophagy initiationAnim Cells Syst (Seoul)May 8, 2025Hyungsun Park, Hansol Heo, Yeongseo Song, Myung Shin Lee, Yebin Cho, Jae-Seon Lee, Jaerak Chang, Seongju LeeEarle’s Balanced Salt Solution (EBSS) (Sigma Aldrich, E3024) or rapamycin (Santa Cruz Biotechnology, sc-3504) for the indicated time. Generation of stable cell lines Stable cell lines were generated via lentiviral

(3) Acinetobacter baumannii OmpA hinders host autophagy via the CaMKK2-reliant AMPK-pathwaymBioApril 9, 2025Kyungho Woo, Dong Ho Kim, Ho-Sung Park, Man Hwan Oh, Je Chul Lee, Chul Hee Choi(Cayman Chemicals, 18477), 40 µM spautin-1 (Sigma, SML0440), or 6 µM rapamycin (Santa Cruz Biotechnology, sc-3504); then infected with A. baumannii; and maintained throughout the course of the experiment. For starvation,

(4) Free Cholesterol‐Induced Liver Injury in Non‐Alcoholic Fatty Liver Disease: Mechanisms and a Therapeutic Intervention Using Dihydrotanshinone IAdvanced ScienceNovember 19, 2024Jia‐Wen Shou, Juncai Ma, Xuchu Wang, Xiao‐Xiao Li, Shu‐Cheng Chen, Byung‐Ho Kang, Pang‐Chui ShawCayman chemical: 5 and 10 μM), bafilomycin A1 (S1413, Selleckchem, Houston, TX, USA: 25 nM), or rapamycin (sc‐3504, Santa Cruz: 500 nM). Flow cytometer analysis (ROS and Apoptosis) Cellular and hepatic levels of reactive

(5) Pleiotrophin Activates cMet- and mTORC1-Dependent Protein Synthesis through PTPRZ1—The Role of ανβ3 IntegrinInternational Journal of Molecular SciencesOctober 9, 2024Eleni Mourkogianni, Katerina Karavasili, Athanasios Xanthopoulos, Michaela-Karina Enake, Lydia Menounou, Evangelia Papadimitriou(Boston, MA, USA #T1661). Rapamycin was from Santa Cruz Biotechnology, Inc. (Heidelberg, Germany, #sc-3504). All the inhibitors were dissolved in dimethylsulfoxide (DMSO). PTN was from PeproTech, Inc. (Rocky

(6) Identification of Small Molecules for Prevention of Lens Epithelium-Derived Cataract Using ZebrafishCellsOctober 29, 2023Kineret Taler, Nour Zatari, Mohammad Iqbal Lone, Shahar Rotem-Bamberger, Adi Inbal(SML2156, Sigma) at a final concentration of 9.2 μM in egg water with 0.003% PTU and 0.2% DMSO; rapamycin (sc-3504, Santa Cruz) at a final concentration of 25 µM in egg water with 0.003% PTU and 0.1% DMSO. In experiments

(7) Autophagy perturbation upon acute pyrethroid treatment impacts adipogenic commitment of mesenchymal stem cellsPesticide biochemistry and physiologySeptember 1, 2023Verma J, Rai AK, Satija NK.

(8) In vitro delivery of mTOR inhibitors by kidney-targeted micelles for autosomal dominant polycystic kidney diseaseSLAS technologyAugust 1, 2023Cox A, Tung M, Li H, Hallows KR, Chung EJ.

(9) mTORC1 activity negatively regulates human hair follicle growth and pigmentationEMBO reportsJuly 5, 2023Suzuki T, Chéret J, Scala FD, Akhundlu A, Gherardini J, Demetrius DL, O''Sullivan JDB, Kuka Epstein G, Bauman AJ, Demetriades C, et al.experimental groups. Rapamycin (final concentration in each rapamycin‐treated well: 20 ng/ml, Santa Cruz, sc‐3504), agouti signaling protein (ASIP)/agouti protein (final concentration in each agouti‐treated well: 2

(10) Immunosuppressants exert differential effects on pan-coronavirus infection and distinct combinatory antiviral activity with molnupiravir and nirmatrelvirUnited European gastroenterology journalJune 1, 2023Wang Y, Li P, Lavrijsen M, Rottier RJ, den Hoed CM, Bruno MJ, Kamar N, Peppelenbosch MP, de Vries AC, Pan Q.

(11) Palbociclib-Induced Cellular Senescence Is Modulated by the mTOR Complex 1 and AutophagyInternational journal of molecular sciencesMay 26, 2023Cayo A, Venturini W, Rebolledo-Mira D, Moore-Carrasco R, Herrada AA, Nova-Lamperti E, Valenzuela C, Brown NE.

(12) Anti-Leukemic Effects of Idesia polycarpa Maxim Branch on Human B-Cell Acute Lymphoblastic Leukemia CellsCurrent issues in molecular biologyMay 4, 2023Kwon CS, Lee JE, Jeon BE, Woo YR, Kim YS, Kim JW, Park CJ, Jang SY, Kim SW.wortmannin (Sigma; St. Louis, MO, USA; W1628), and rapamycin (Santa Cruz Biotechnology; Dallas, TX, USA; sc-3504). The primary antibodies against Bcl-2 (Santa Cruz Biotechnology; Dallas, TX, USA; sc-7381), Mcl-1 (Santa Cruz Biotechnology

(13) FPR1 is essential for rapamycin-induced lifespan extension in Saccharomyces cerevisiaeBiochemical and biophysical research communicationsApril 23, 2023Yalcin G, Kim J, Seo D, Lee CK.

(14) Zebrafish Larvae Position Tracker (Z-LaP Tracker): a high-throughput deep-learning behavioral approach for the identification of calcineurin pathway-modulating drugs using zebrafish larvaeScientific reportsFebruary 23, 2023Gore SV, Kakodkar R, Del Rosario Hernández T, Edmister ST, Creton R.

(15) PI3-kinase deletion promotes myelodysplasia by dysregulating autophagy in hematopoietic stem cellsScience advancesFebruary 22, 2023Ames K, Kaur I, Shi Y, Tong MM, Sinclair T, Hemmati S, Glushakow-Smith SG, Tein E, Gurska L, Steidl U, et al.methylcellulose was supplemented with rapamycin (final concentration, 20 ng/ml; Santa Cruz Biotechnology, SC-3504) or metformin (final concentration, 50 μM; Enzo Life Sciences, 270-432-G005). BM transplantation For

(16) Xanthatin suppresses proliferation and tumorigenicity of glioma cells through autophagy inhibition via activation of the PI3K-Akt-mTOR pathwayPharmacology research & perspectivesFebruary 1, 2023Chen H, Zhu T, Huang X, Xu W, Di Z, Ma Y, Xue M, Bi S, Shen Y, Yu Y, et al.A1)(Abcam, AB120497), autophagy inducers Torin1 (Selleckchem, S2827), and rapamycin (Rapa) (Santa Cruz, sc‐3504), PI3K/mTOR inhibitor NVP‐BEZ235 (MedChemExpress, HY‐50673). Sulforhodamine B cell proliferation and

(17) FLIP-based autophagy-detecting technique reveals closed autophagic compartmentsScientific reportsDecember 27, 2022Sakurai HT, Arakawa S, Noguchi S, Shimizu S.

(18) Inhibition of mTORC1 differentially affects ribosome biogenesis in rat soleus muscle at the early and later stages of hindlimb unloadingArchives of biochemistry and biophysicsNovember 15, 2022Rozhkov SV, Sharlo KA, Shenkman BS, Mirzoev TM.

(19) Lignin-carbohydrate complexes suppress SCA3 neurodegeneration via upregulating proteasomal activitiesInternational journal of biological macromoleculesOctober 1, 2022Chen ZS, Yan M, Pei W, Yan B, Huang C, Chan HYE.

(20) Modulation of calcineurin signaling during developmentDevelopmental neurobiologySeptember 1, 2022Tucker Edmister S, Creton R.

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Rapamycin Chemicals

Rapamycin from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Rapamycin from Santa Cruz Biotechnology, Inc.

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