Fig 1: Long-term killing assays. Residual viable ALL cells at 3 time points of co-culture H0 (starting point), after 4 h (H4) of co-culture and after 24 h (H24) of co-culture: (a) with no effector, results showed total viable cells; (b) with a purified autologous anti-CD19 CAR-T cell preparation (percent of residual CD22+ viables cells); (c) with anti-HLA DPB1*04:01 CD4+ T-clone (percent of residual CD22+ viables cells); (d) with anti-CMVpp65 CD8 T-cells (percent of residual CD22+ viables cells). Two experiments in duplicate were performed at effector/ratio = 3:1. Results are given as mean + SD. CMVpp65 peptides: PepTivator CMVpp65 human, 130-093-435, Miltenyi Biotec; T eff: T-cell effectors, here polyclonal CD8+ T cells against CMV peptides.