NK-92 from ATCC

Product Specs
ItemNK-92
CompanyATCC
Price $431.00Supplier Page View Company Product Page
Catalog NumberCRL-2407
ApplicationsThis cell line is a suitable transfection host. The cell line is cytotoxic to a wide range of malignant cells; it kills both K562 cells and Daudi cells in chromium release assays. NK-92® cells (after irradiation to prevent proliferation) can be used effectively for immunological ex vivo purging of leukemia from blood without compromising hematopoietic cell function
TypeCell Biology
SpeciesHomo sapiens
TissuePeripheral blood
Cell LineNK-92
Validated Species ReactivityHuman (Hu)
Cell Type (standardized)NK Cells
Cell Typenatural killer cell and nk cell
Age50 years
DiseaseMalignant Non Hodgkins Lymphoma

Specifications/Features

Post freeze viability ≥ 50%

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ATCC

10801 University Boulevard

Manassas, Virginia 20110-2209

United States

Phone: (703) 365-2700
Fax: (703) 365-2701

Company Profile

Website: http://www.atcc.org

(1) Immune-induced TCR-like antibodies regulate specific T cell response in miceNat CommunApril 16, 2026Kazuki Kishida, Keisuke Kawakami, Hiroaki Tanabe, Wataru Nakai, Koji Yonekura, Shigeyuki Yokoyama, Hisashi Arasepurchased from the RIKEN Cell Bank, and LK35.2 cells (ATCC HB-98) expressing I-Ak and NK92 cells (ATCC CRL-2407) were obtained from the American Type Culture Collection. The invariant chain (Ii) or H-2Mα deleted

(2) PTPN1/PTPN2 inhibition improves NK cancer therapy by enhancing IL-2 and mitigating TGFβ1 responsesEMBO ReportsApril 15, 2026Chu-Han Feng, Linda Peltier, Tiffanie Chouleur, Milea DiPonzio, Isabelle Aubry, Alexandre J Poirier, Zuzet M Cordova, Yunyun Shen, Sébastien Tabariès, Xiaona Cao, et al.Laneuville’s and Dr. Linda Peltier’s Lab (McGill University Health Center)/ This study, NK-92 cells,ATCC,CRL-2407 K-562 cells,ATCC,CCL-243 Reh cells,ATCC,CRL-8286 Jurkat cells,ATCC,TIB-152 HEK293T/17 cells,ATCC,ACS-4500 HCT116 cells

(3) A fully human pan VL9 HLA-E TCRm antibody enables functional dissection of HLA-E biology and checkpoint signalingiScienceApril 9, 2026Soroush Ghaffari, Katherine Upchurch-Ange, Gizem Oter, Trivendra Tripathi, Susanne Gimlin, Debra Wawro Weidanz, Jim Middelburg, Thorbald van Hall, Jon A. WeidanzVan Hall,RIID:CVCL_0108 K562,Dr.Van Hall,RRID:CVCL_0004 K562.HLA-E,Dr. M. Lampen,N/A NK92,ATCC,CAt#CRL-2407; RRID:CVCL_2142 RPMI-8226,ATCC,Cat#CRM-CCL-155; RIID:CVCL_0014 SU.86.86,ATCC,Cat#CRL-1837; RIID:CVCL_3881 EBY100,ATCC,Cat#MYA-4941 ,, Experimental models

(4) IL-7Rα signaling potentiates the anti-tumor activity of NK92 cellsFrontiers in ImmunologyMarch 30, 2026Chunli Wang, Seokmin Kim, Ling-Zu Kong, Inhwan Jang, Seona Jo, Sunyoung Lee, Soo Yun Lee, Kee K. Kim, Tae-Don KimNK cell immunotherapy. Methods and materials Cell culture NK92 (human natural killer cell line, ATCC®CRL-2407™), MDA-MB-231 (Human breast cancer cell line, ATCC®CRM-HTB-26™), NCI-H460 (human non-small cell lung cancer

(5) Engineering NK and T cells with metabolite-sensing receptors to target solid tumorsNature ImmunologyMarch 23, 2026Young-Min Kim, Min K. Tsai, Chang Sun, Olivia Laveroni, Reece Villarin Akana, Kristen Frombach, Livnat Jerby18% protein rodent diet (Envigo) and were provided ad libitum access to water. Cell lines NK-92 (CRL-2407), MDA-MB-231 (HTB-26), MCF7 (HTB-22) and E0771 (CRL-3461) cells were purchased from ATCC. Lenti-X 293T cells

(6) Combining lenalidomide with IL-2 family of cytokines enhances activating receptor and perforin/granzyme expression in NK cellsPLoS OneMarch 12, 2026Alexandra Calescibetta, Robert Dalton, Nicole Fortenbery, Grace Ward, Sean Christiansen, Xianghong Chen, Pingyan Cheng, Tiffany Razabdouski, Annelise J. Glode, Nhan Tu, et al.an IL-2 independent cell line originally derived from YT cells (CVCL_D324, RRID:CVCL_D324); NK-92 (CRL-2407, ATCC, Manassas, Virginia, RRID:CVCL_2142) and NKL (LGL cell line, RRID:CVCL_0466) are both IL-2 dependent

(7) Enhancement of NK cell activity via DNA-sensing inhibition by Poxin transgeneJournal of Advanced ResearchMarch 1, 2026Ling-Zu Kong, Seok-Min Kim, Soo Yun Lee, In-Hwan Jang, Chunli Wang, Seona Jo, Se-Chan Oh, Sunyoung Lee, Ji Hyun Kim, Kee K. Kim, et al.in cancer therapy. Materials and methods Cell culture The human natural killer cell line NK-92 (CRL-2407) and human monocyte cell line THP-1 (TIB-202) were obtained from ATCC and cultured at 37 °C in an atmosphere

(8) Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populationsCell ReportsFebruary 24, 2026Xiaowen Hu, Jie Huang, Jiao Yuan, Yanrong Sun, Yuxin Wang, Zhongyi Hu, Junjie Jiang, Zhiling Wang, Bingwei Wang, Meixiao Long, et al.lines 293T,ATCC,Cat #CRL-3216; RRID: CVCL_0063 CAL27,ATCC,Cat #CRL-2095; RRID: CVCL_1107 NK-92,ATCC,Cat #CRL-2407; RRID: CVCL_2142 Jurkat,ATCC,Cat #TIB-152; RRID: CVCL_0065 HCC1143,ATCC,Cat #CRL-2321; RRID: CVCL_1245 NCI-H1373,ATCC,Cat

(9) Development and evaluation of an inhalable nanoemulsion system for enhancing NK cell function against osteosarcoma pulmonary metastasesFrontiers in ImmunologyFebruary 12, 2026Sookyung Hwang, Paul D. Bates, Vasiliki Valkanioti, Chih-Chun Chang, Sandro Mecozzi, Christian M. CapitiniMN). hSAEC primary small airway epithelial cells (Cat #PCS-301-010), NK-92 human NK cell lymphoma (Cat #CRL-2407), MG63 human osteosarcoma (Cat #CRL-1427), and K7M2 murine osteosarcoma (Cat #CRL-2836) cell lines were

(10) Dual-functioning Targeted ADAM17 Blocker CD16 (TAB16) mediates selective ADAM17 inhibition in NK cells and engages overexpressed ADAM17 in tumor cells to induce cytotoxicityFrontiers in ImmunologyJanuary 30, 2026Kate J. Dixon, Robert Hullsiek, Sam Wang, Ryan R. Friess, Anders W. Matson, Yvette Soignier, Alexander J. Lenvik, Jianming Wu, Geoffrey T. Hart, Martin Felices, et al.analyzed via flow cytometry. SKOV-3 cells (HTB-77), an ovarian adenocarcinoma cell line, and NK-92 (CRL-2407) cells were purchased from ATCC (Manassas, VA, USA). SKOV-3 cells stably expressing NucLightRed (NLR)

(11) Convergent Roles of Growth Differentiation Factor-15 (GDF-15) in Mechanotransduction, Vascular Disorganization, and Immune Suppression in MelanomabioRxivJanuary 21, 2026Yu-Chi Chen, Vishnu Sravan Bollu, Sina Kheirabadi, Kyle LaPenna, Arthur Berg, Ping He, Todd D. Schell, Amir Sheikhi, Erdem D. Tabdanov, Gavin P. RobertsonRPMI-1640/10% FBS. Target cells were plated at 2×104/well in 96-well round-bottom plates. NK-92 cells (ATCC CRL-2407) were grown in RPMI-1640 containing 10% FBS and 15% Horse Serum (Gibco) with 10 ug/ml recombinant human IL-2

(12) SAMSN1 restrains NK cell mediated anti-tumor immunity in hepatocellular carcinomaNature CommunicationsJanuary 21, 2026Ruifeng Wang, Huidi Chen, Hanyang Liu, Qiang Li, Guojing Yao, Fuling Li, Peng Sun, Tianli Dai, Jiabei Wang, Björn Nashan, et al.B16-F10-luc cell lines were maintained in DMEM containing 10% FBS. NK92 cells were purchased from ATCC (Cat: CRL-2407) and maintained according to the protocol provided by ATCC. NK92 overexpression and knockout cell lines

(13) Bromodomain and extra-terminal protein inhibitors modulate natural killer cell function and differentiationScientific ReportsJanuary 3, 2026Eric S. Geanes, Gage Greening, Maria Aggelakopoulou, Linh Huyen Truong, Santosh Khanal, Cas LeMaster, Marc Herman, Rebecca McLennan, Persephone Borrow, Todd Bradleyother demographic information was unknown. Cell line culture NK-92 cells were purchased from ATCC (CRL-2407). Cells were passaged twice after thawing before any experiments were performed. NK-92 Media composition

(14) Trained Immunity: RoadMap for drug discovery and developmentElifeDecember 23, 2025Jelmer H van Puffelen, Callum Campbell, Irene Gander-Meisterernst, Johanna Holldack, Pauline T Lukey,NATURAL KILLER CELLS,NATURAL KILLER CELLS Cell line,NK-92; Natural Killer Cell,Human,ATCC Product Code: ATCC-CRL-2407,https://www.lgcstandards.com/GB/en/search?text=natural%20killer%20cells Cell line,NK101,Human,RRID:CVCL_WN95,https://www.cellosaurus.org/CVCL_WN95 Primary,CD56+

(15) Trained Immunity: RoadMap for drug discovery and developmentElifeDecember 23, 2025Jelmer H van Puffelen, Callum Campbell, Irene Gander-Meisterernst, Johanna Holldack, Pauline T Lukey,NATURAL KILLER CELLS,NATURAL KILLER CELLS Cell line,NK-92; Natural Killer Cell,Human,ATCC Product Code: ATCC-CRL-2407,https://www.lgcstandards.com/GB/en/search?text=natural%20killer%20cells Cell line,NK101,Human,RRID:CVCL_WN95,https://www.cellosaurus.org/CVCL_WN95 Primary,CD56+

(16) ALFQ adjuvanted HIV-1 envelope protein vaccination elicits durable functional antibody and cellular responses in nonhuman primatesNPJ VaccinesDecember 19, 2025Shikha Shrivastava, Joshua M. Carmen, Jiae Kim, Kristina K. Peachman, Shraddha Basu, Ryan Alving, Danielle Nettere, Gautam Kundu, Lauren Yum, Mohammad Arif Rahman, et al.performed according to the manufacturer’s protocol. Generation of NK92.rhCD16 cell line NK92 cells (ATCC CRL-2407) are a human NK-cell line derived from an individual with malignant non-Hodgkin lymphoma. The cells

(17) 2B4 co-stimulation and dasatinib modulation enhance anti-CD19 CAR-NK-92 cell cytotoxicityFront ImmunolDecember 12, 2025Matheus Henrique Dos Santos, Júlia Teixeira Cottas de Azevedo, Mara Elisama da Silva Januário, Dayane de Fátima Schmidt, Mariane Cariati Tirapelle, Alison Felipe Bordini Biggi, Sima Ebrahimabadi, Renata Nacasaki Silvestre, Dimas Tadeu Covas, Rodrigo T. Calado, et al.efficacy. 2 Materials and methods 2.1 Cells and culture conditions Natural Killer (NK-92) cell line (ATCC, CRL-2407™) was cultured in serum-free X-VIVO 10 medium (Lonza, Cologne, Germany) supplemented with 5% heat-inactivated

(18) Development of potent Affitin-based bispecific NK cell engagers for the therapy of MSLN-expressing cancersMolecular Therapy OncologyNovember 19, 2025Tina Briolay, Tacien Petithomme, Hermelyne Gravoueille, Judith Fresquet, Sylvia Lambot, Pauline Cossard, Barbara Mouratou, Agnès Fortun, Karine Bernardeau, Agnès Quéméner, et al.referred to as Meso34-MSLN/BFP. The NK-92 cell line from the American Type Culture Collection (ATCC) (CRL-2407) was stably transfected with a vector encoding human CD16 (NK92CD16h) and used as the effector in these

(19) NK cell function down regulated by HMGB2 through ANGPT1/PI3K/AKT pathway and its effect on esophageal squamous carcinoma cellsFrontiers in ImmunologyNovember 7, 2025Xiaodi Yin, Huihong Cai, Aohua Zhang, Weihan Zheng, Jiahui Zhao, Jun Mausing MaxQuant software (version 1.6.17.0). 2.2 Cell culture The human NK cell line NK-92 (ATCC, CRL-2407, USA) was cultured in alpha-MEM supplemented with 12.5% fetal bovine serum (Biological Industries, Israel,

(20) Lightweight CNN efficiently discriminates ovarian cancer cells from a tumor microenvironment via holographic imaging flow cytometryBiomedical Optics ExpressNovember 1, 2025Daniele Pirone, Beatrice Cavina, Giusy Giugliano, Michela Schiavo, Lisa Miccio, Vittorio Bianco, Francesca Nanetti, Francesca Reggiani, Giuseppe Gasparre, Ivana Kurelac, et al.line CAOV3 was purchased from ATCC (#HB-75). Natural killer NK92 cell line was purchased from ATCC (#CRL-2407). Umbilical Vein Endothelial, Pooled Donors (HUVEC) cells were purchased from Lonza (#CC-2519). Monocyte

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NK-92 from ATCC

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