ARGO™ HT System from Alamar Biosciences

Product Specs
ItemARGO™ HT System
CompanyAlamar Biosciences
Price Inquire
Catalog NumberARGO HT
DetectionAlamar has turned NULISA technology into a turnkey protein analysis workstation with the ARGO™ HT System. The ARGO HT System, a fully automated, high-throughput precision proteomics platform, performs ultra-high sensitivity and multiplexed analysis to support broad biomarker profiling, validation, and translation into clinical use.
ApplicationsSingle-plex and multiplex NULISA™ assays

(1) Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cellsInternational Journal of CancerMay 15, 2026Samuel T. Orange, Emily Dodd, Sharanya Nath, Hannah Bowden, Alastair R. Jordan, Hannah Tweddle, Ann Hedley, Ifeoma Chukwuma, Ian Hickson, Sweta Sharma Sahacentrifuged at 2200 g for 10 min. A 25 μL aliquot of supernatant was assayed on the automated Alamar ARGO HT system (Alamar Biosciences) at Altheome Limited laboratories (London, UK). Following immunocomplex formation

(2) Pre-analytical guidelines for blood and CSF Biomarkers 2025: Recommendations from the NACC ADRC Biofluid Biomarker Best Practices WorkgroupAlzheimers DementMay 4, 2026Timothy E. Van Meter, Edward N. Wilson, Fanny Elahi, Robert A. Rissman, Argentina Lario Lago, Kelley Faber, Kathryn Gauthreaux, Ricardo Osorio, Matthew Perkins, Nora Gray, et al.HD‐X1), Fujirebio Lumipulse G 1200, and multiplex discovery platforms including Alamar Biosciences ARGO HT, Somalogic Somascan, and mass spectroscopy. Note that mass spectroscopy is often used for discovery,

(3) Distinct phases of immune system programming during ART-suppressed immunodeficiency virus infectionbioRxivMay 1, 2026Maanasa Kaza, Benjamin Varco-Merth, G W McElfresh, Sebastian Benjamin, Gregory J. Boggy, Morgan Chaunzwa, Shana Feltham, Sohita Ojha, Karina Belica, Andrea N. Selseth, et al.Inflammation Panel 250 targeting mostly inflammation and immune response-related cytokines and chemokines. The ARGO™ HT platform was used to perform the NULISA workflow, starting with immunocomplex formation with DNA-barcoded

(4) Loss of neuronal population organization links pathology to behavior in a model of Alzheimer’s diseasebioRxivMarch 23, 2026Douglas A. Ruff, Drew E.G. Sheets, Ramanujan Srinath, Giovanne B. Diniz, Devon J. Griggs, Danielle Beckman, Sean Ott, Kayla Schwartz, Carissa Erices, Scott Muller, et al.compensate for technical variability. All assay steps were executed automatically using a preprogrammed ARGO HT system (Alamar Biosciences). Pooled sequencing libraries were generated and sequenced on an AVITI benchtop

(5) Head-to-head comparison of brain-derived pTau217 and total pTau217 for brain amyloid and tau pathology classificationProc Natl Acad Sci U S AMarch 10, 2026Yuanbing Jiang, Wenyue Zheng, Zengjie Xia, Wan Wa Wong, Lily K. W. Cheng, Fanny C. Ip, Siu Man Choi, Andrew L. T. Chan, Ching Yu Lam, Ka Shing Ho, et al.Appendix, Table S4). Plasma BD-pTau217 Measurement. We measured plasma BD-pTau217 levels on an Alamar ARGO HT system using the commercially available NULISAqpcr BD-pTau217 Assay (Cat. No. 801430, Alamar Biosciences).

(6) Blood-based proteomic signatures of spontaneous menopause: Implications for later-life brain aging and Alzheimer’s disease riskmedRxivFebruary 14, 2026Madeline Wood Alexander, Jennifer S. Rabin, Michelle Caunca, Allesandra Iadipaolo, Louisa Cornelis, Nina Miolane, Albert Pham, Julia Borger, Valentina Diaz, Emily W. Paolillo, et al.cohorts, see below) was analyzed on the NULISAseq CNS panel (~120 proteins) using the automated Alamar Argo HT workflow (Extended Data). Aging cohorts To evaluate the relevance of menopause-related biological

(7) Blood-based proteomic signatures of spontaneous menopause: Implications for later-life brain aging and Alzheimer’s disease riskResearch SquareFebruary 12, 2026Madeline Wood Casaletto, Madeline Wood Alexander, Jennifer Caunca, Allesandra Iadipaolo, Allesandra Iadipaolo, Louisa Cornelis, Albert Miolane, Albert Borger, Valentina Borger, Valentina Paolillo, et al.cohorts, see below) was analyzed on the NULISAseq CNS panel (~120 proteins) using the automated Alamar Argo HT workflow (Extended Data). Aging cohorts To evaluate the relevance of menopause-related biological

(8) Plasma vs. serum: which is better for proteomic blood biomarker analysis? Evaluation of the novel NULISA platformmedRxivJanuary 16, 2026Marissa F. Farinas, Yijun Chen, Xuemei Zeng, Michel N. Nafash, Ann D. Cohen, Oscar I. Lopez, Thomas K. Karikariparticulates. The supernatants were analyzed using the NULISAseq CNS disease panel 120 (v2) on an Alamar ARGO™ HT system as previously described [25]. Briefly, samples were incubated with a cocktail of paired capture and

(9) The National Centralized Repository for Alzheimer's Disease and Related Dementia's Biomarker Assay Laboratory: A Resource for the Alzheimer's Disease Research CommunityAlzheimer's & DementiaNovember 6, 2025Kristen A. Russ, Kaci Lacy, Jeffrey L. Dage, Tatiana Foroud1080 automated liquid handlers, two Quanterix Simoa HD‐X, a Fujirebio Lumipulse G1200, and an Alamar ARGO HT for use with NULISAseq technology. The lab is currently equipped and staffed to analyze approximately

(10) Characterizing the physiology of circulatory arrest in humansNat MedOctober 16, 2025Jordan D. Bird, Laura Hornby, Veronica Hirsch-Reinshagen, Chloe P. Allen, George Isac, Peter A. Gooderham, Sam D. Shemie, Sonny Dhanani, Sonny Thiara, Sophie Stukas, et al.analysis of plasma samples was performed using the NULISAseq CNS Disease Panel 120 (800104) on the ARGO HT platform (Alamar Biosciences). Biospecimens were thawed and centrifuged at 10,000g for 10 min to remove

(11) Identifying a Biological Signature of Trauma-Related Neurodegeneration Following Repeated Traumatic Brain Injuries Compared with Healthy ControlsNeurotrauma ReportsJuly 9, 2025Shawn R. Eagle, Ava Puccio, Sarah Svirsky, James Mountz, Charles Laymon, Allison Borasso, Luke Henry, David O. Okonkwophosphorylated transactive response DNA-binding protein 43 (pTDP-43) were measured using the automated Alamar Argo HT workflow. Sample controls, internal controls, inter-plate controls, and negative controls were all included

(12) Targeted proteomic biomarker profiling using NULISA in a cohort enriched with risk for Alzheimer's disease and related dementiasAlzheimer's & DementiaMay 2, 2025Ramiro Eduardo Rea Reyes, Rachael E. Wilson, Rebecca E. Langhough, Rachel L. Studer, Erin M. Jonaitis, Julie E. Oomens, Elizabeth M. Planalp, Barbara B. Bendlin, Nathaniel A. Chin, Sanjay Asthana, et al.reagent kit. The plate was sealed and spun for 1 min at 1000 × g and 4°C. Utilizing the automated Alamar Argo HT workflow, target analytes within each sample were bound through multiple capture, wash, and release

(13) Alzheimer blood biomarkers: practical guidelines for study design, sample collection, processing, biobanking, measurement and result reportingMolecular NeurodegenerationMay 15, 2024Xuemei Zeng, Yijun Chen, Anuradha Sehrawat, Jihui Lee, Tara K. Lafferty, Julia Kofler, Sarah B. Berman, Robert A. Sweet, Dana L. Tudorascu, William E. Klunk, et al.(2.7–10,290)",• Can simutenously measure up to 8 plexes• Sample volume: 25 μL per analysis Alamar (ARGO HT) [73],NULISA™,"Aβ40, Aβ42, p-tau181, p-tau217, p-tau231, NfL, GFAP, t-tau",• Both singleplex or multiplex

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ARGO™ HT System from Alamar Biosciences

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ARGO™ HT System from Alamar Biosciences

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