Caspase-3 Inhibitor from Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

(1) Bone marrow mesenchymal stem cell-derived extracellular vesicles promote corneal epithelial repair and suppress apoptosis via modulation of Caspase-3 in vitroFEBS open bioJune 1, 2024Tati V, Mitra S, Basu S, Shukla S.also used for validation of apoptosis. Pre‐treatment of HCECs with a Caspase‐3 inhibitor: Z‐DEVD‐FMK (#sc‐3075, Santa Cruz Biotechnology, Inc.; 10 μM for 1 h [32]) was used to evaluate the Caspase‐3 dependent modulation

(3) Cell death mechanisms induced by synergistic effects of halofuginone and artemisinin in colorectal cancer cellsInternational journal of medical sciencesJanuary 1, 2022Gong RH, Yang DJ, Kwan HY, Lyu AP, Chen GQ, Bian ZX.

(4) Luteolin attenuates hepatic injury in septic mice by regulating P2X7R-based HMGB1 releaseFood & functionNovember 1, 2021Zhang ZH, Yang HX, Jin Q, Wu YL, Cui ZY, Shang Y, Liu J, Zhan ZY, Lian LH, Nan JX.

(6) Granzyme B Induces IRF-3 Phosphorylation through a Perforin-Independent Proteolysis-Dependent Signaling Cascade without Inducing Cell DeathJournal of immunology (Baltimore, Md. : 1950)January 15, 2021Gapud EJ, Trejo-Zambrano MI, Gomez-Banuelos E, Tiniakou E, Antiochos B, Granville DJ, Andrade F, Casciola-Rosen L, Rosen A.

(8) Sophoraflavanone G from Sophora flavescens induces apoptosis in triple-negative breast cancer cellsPhytomedicine : international journal of phytotherapy and phytopharmacologyAugust 1, 2019Huang WC, Gu PY, Fang LW, Huang YL, Lin CF, Liou CJ.

(11) SERPINB1-mediated checkpoint of inflammatory caspase activationNature immunologyMarch 1, 2019Choi YJ, Kim S, Choi Y, Nielsen TB, Yan J, Lu A, Ruan J, Lee HR, Wu H, Spellberg B, et al.

(14) Targeting the Difficult-to-Drug CD71 and MYCN with Gambogic Acid and Vorinostat in a Class of NeuroblastomasCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2019Bishayee K, Habib K, Sadra A, Huh SO.

(16) The Marine Dinoflagellate Alexandrium andersoni Induces Cell Death in Lung and Colorectal Tumor Cell LinesMarine biotechnology (New York, N.Y.)June 1, 2018Sansone C, Nuzzo G, Galasso C, Casotti R, Fontana A, Romano G, Ianora A.

(17) Inhibition of cancer progression by a novel trans-stilbene derivative through disruption of microtubule dynamics, driving G2/M arrest, and p53-dependent apoptosisCell death & diseaseMay 1, 2018Parida PK, Mahata B, Santra A, Chakraborty S, Ghosh Z, Raha S, Misra AK, Biswas K, Jana K.colorimetric assay kit (#ab39401) was obtained from Abcam (USA). Inhibitors to caspase 3 (Z-DEVD-FMK #sc3075), caspase 8 (Z-IETD-FMK #sc3084), and Pan-caspase (Z-VAD-FMK #sc3067) were ordered from Santa Cruz Biotechnologies