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Cell Biology
Inhibitors
Ac-YVAD-CMK
Ac-YVAD-CMK from Enzo Life Sciences, Inc.
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Citations:
(2)
Supplier Page
Supplier Page from
Enzo Life Sciences, Inc. for
Ac-YVAD-CMK
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Description
Irreversible, cell permeable inhibitor of caspase-1. Also inhibits caspase-4. Inhibits Fas-mediated apoptosis
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Ac-YVAD-CMK
Company
Enzo Life Sciences, Inc.
Price
$89.00
Supplier Page
View Company Product Page
Catalog Number
ALX-260-028-M001
Quantity
1 mg
Purity
≥96% (HPLC)
Sample Type
White to off-white powder
Molecular Weight
541.0
Molecule Name
Ac-YVAD-CMK
Formula
C
24
H
33
N
4
O
8
Cl
Type
Peptide
Specifications/Features
Inhibitor of caspase-1 and -4
Sequence
Ac-Tyr-Val-Ala-Asp-chloromethylketone
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Enzo Life Sciences, Inc.
10 Executive Blvd.
Farmingdale
,
NY
11735
United States
Phone
: 800-942-0430
Fax: 610-941-9252
Company Profile
Website:
www.enzo.com
Citations (2)
(1)
Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4
Cell reports
December 19, 2017
Van Opdenbosch N, Van Gorp H, Verdonckt M, Saavedra PHV, de Vasconcelos NM, Gonçalves A, Vande Walle L, Demon D, Matusiak M, Van Hauwermeiren F,
et al
.
(Sigma-Aldrich), or the caspase-1 inhibitor Acetyl-Tyr-Val-Ala-Asp - chloromethylketone (
Ac-YVAD-cmk
) (
ALX-260-028-M001
,
Enzo Life Sciences
) was measured for 20 min at 1-min intervals by
fluorometry
(excitation at 360 nm
(2)
Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5
Proceedings of the National Academy of Sciences
February 3, 2015
Magdalena Matusiak, Nina Van Opdenbosch, Lieselotte Vande Walle, Jean-Claude Sirard, Thirumala-Devi Kanneganti, Mohamed Lamkanfi
S5265-25KU, Sigma), as described (17). In some experiments, cells were pretreated with
Ac-YVAD-cmk
(50 μM,
ALX-260–028-M001
,
Enzo Life Sciences
) for 30 min before S. Typhimurium
infection
or fliC
transfection
. Otherwise, cells
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Ac-YVAD-CMK from Enzo Life Sciences, Inc.
Supplier Page
View Company Product Page
$89.00
Product Specs
Company Info
Citations
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