scanR High Content Screening Station from Evident

Product Specs
ItemscanR High Content Screening Station
CompanyEvident
Price Get Pricing Get Quote for this Product
Catalog NumberscanR
QuantityEA
ApplicationsHigh-content screening, standard assays, assay development
TypeHigh-Content Screening Station
Software2 independent software modules: scanR acquisition software and scanR analysis software
Light SourceLED

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Evident

48 Woerd Avenue

Waltham, MA 02453

United States

Phone: 1-800-446-5967

Company Profile

Website: EvidentScientific.com

(1) Stereochemical Aspects in the Context of the Structure–Activity Relationship of Chlorido[ N , N ′-bis(chloro/bromosalicylidene)-1,2-diphenyl-1,2-diaminoethane]iron(III) ComplexesJournal of Medicinal ChemistryMay 14, 2026Astrid Dagmar Bernkop-Schnürch, Stefanie Schwarz, Philipp Rigo, Daniel Leitner, Mostafa Alilou, Martin Hermann, Michael Seidl, Magnus Andre Kiechle, Sofie Hanifle, Stephan Hohloch, et al.treated with the complexes 1a–c at concentrations of 1 μM and 10 μM and incubated at 37 °C in the Evident ScanR live-cell imaging system for 72 h. Pictures were taken initially 5 min after addition of the complexes

(2) Patient-derived AMOTL1 mutations lead to defective cell migration and tissue developmentBiosci RepMay 11, 2026Jiaqian Luo, Ruxin Jin, Fang Geng, Yunying Wang, Yuwen Zhu, Wenqiang Gao, Wei Gao, Jian Li, Yaming Jiu, Ruilin Zhang, et al.replenished. Cell migration into the open space (wound) created was monitored for 24 h using an Olympus scanR high-content screening station. Each evaluated sample was plated in triplicate. Videos were processed with ImageJ software. Wound closure

(3) TCA cycle rewiring underpins histone acetylation sourcing and cell-fate transitions during exit from naive pluripotencyCell Stem CellMay 7, 2026Eleni Kafkia, David Pladevall-Morera, Lidia Argemi-Muntadas, Gangqi Wang, Roberta Noberini, Arnau Casòliba-Melich, Sandra Bagés-Arnal, Matthias Anagho-Mattanovich, Rita Silvério-Alves, Johanna Gassler, et al.each well in a 96-well plate, 12 images composed of 30 Z-fields separated by 1μm each were taken. The ScanR analysis software (version 3.2.0, r4066 x64, Olympus) was used for image segmentation and quantification

(4) Correction of the molecular phenotype of X-linked Dystonia-Parkinsonism reveals a non-canonical function of BRD4Nat CommunMay 5, 2026Simona Capponi, Sandra Ehret, Zeynep Camgöz, Fabian Gather, Christine A. Vaine, Ezgi Özyerli-Göknar, Marie Follo, D. Cristopher Bragg, Tanja Vogel, H. Th. Marc Timmersquadruplicates and each plate included a DMSO control. Live-cell imaging was performed using the Olympus ScanR high-content screening station taking nine images for each well on the GFP, mCherry (for mKATE2 imaging) and DAPI channels with the

(5) Slow RNAPII elongation enhances naive pluripotency rewiring while maintaining high replication fork speedSci AdvApril 24, 2026Sara Martín-Vírgala, Joana Segura, Alicia Gallego, Ran Tong, Sara Tur-Gracia, Jesús Rafael Rodriguez-Aguilera, Biswajit Das, Javier Isoler-Alcaraz, Carlos Gallego-García, Shraddha Shinde, et al.cytometry QIBC experiments for detection of γH2AX along the cell cycle were performed on an Olympus ScanR inverted wide-field microscope system based on an IX83 inverted motorized frame (Evident) equipped with

(6) MRE11 proximal polyadenylation site-mediated looping impacts transcription and genomic stabilityMol CellApril 16, 2026Kaimeng Huang, Marie Eve Brault, Ke Cong, Narmen Azazmeh, Sarah Collins, Siyun Lee, George A. Lantz, Gregory Raskind, Gaëlle Legube, Rameen Beroukhim, et al.(v2.7.3a),Dobin et al75,https://github.com/alexdobin/STAR SvABA,N/A,https://github.com/walaj/svaba scanR acquisition and analysis software (3.6.0),Olympus,N/A Other,Other,Other "DMEM, High glucose, pyruvate",Life Technology

(7) Dispensable players: N-WASP and WASP are not crucial for homology-directed DNA repairEMBO ReportsApril 10, 2026Thu Han Le Phan, Anders Buchard, Cord Brakebuschstaining using 1 μg/mL DAPI (Thermo Scientific, 62248; Waltham, MA, USA). Images were acquired using ScanR High-Content Screening Station (Olympus; Tokyo, Japan) with a UPlanSApo 20×/0.75 air objective and analyzed with CellProfiler v.4.2.6

(8) Neural cell state modulation by PARK2 and dopaminergic neuroprotection by small molecule Parkin agonismbioRxivApril 4, 2026Yongxing Gong, Armin Bayati, Tyler J. Alban, Prerana Parthasarathy, Fang Zhou, Vladimir Makarov, Yuhang Zhao, Chienwen Su, Jackson G. Schumacher, Vijay Singh, et al.concentration of 2.8μg/ml in conjunction with 1 μg/ml Hoechst33342. Cells were imaged using an Olympus ScanR automated microscope equipped with a motorised stage and 20x APO planar objective. 18 images were acquired

(9) Distinct mechanisms of replication stress induced by oncogenic RAS and cyclin E1 converge on R-loop-dependent fork reversalNature CommunicationsApril 3, 2026Anna Oravetzova, Marketa Dvorakova, Anca-Irina Mihai, Martin Andrs, Margarita Sobol, Anton Zuev, Kaustubh Shukla, Barbora Boleslavska, Vinicio Rosano, Christiane König, et al.upright fluorescent microscope (63 × /1.40 oil immersion), an IX83 microscope (Olympus) equipped with the ScanR imaging platform using a 60x/1.42 OIL objective with oil immersion, or an IXplore SpinSR10 (Olympus)

(10) CDK12/CDK13 inhibition disrupts transcriptional elongation and replication fork progression in glioblastomaEMBO Molecular MedicineMarch 25, 2026Silje Lier, Sara B Markusson, Anja Kocijancic, Martine Narum, Solveig O Lund, Bianka Böllering, Anuja Lipsa, Mirra L C Søegaard, Idun D Rein, Petra Santha, et al.previously described (Somyajit et al, 2017; Toledo et al, 2013). Briefly, images were acquired with a ScanR inverted microscope high-content screening station (Evident IX83 inverted microscope) equipped with

(11) DIS3 mutations enhance AID-driven translocations during B-cell activation, promoting transformation to multiple myelomaNature CommunicationsMarch 14, 2026Tomasz M. Kuliński, Olga Gewartowska, Mélanie Mahé, Karolina Kasztelan, Nina Durys, Anna Stroynowska-Czerwińska, Marta Jedynak-Slyvka, Ewelina P. Owczarek, Debadeep Chaudhury, Marcin Nowotny, et al.fluorescence microscope with 40×/0.95 apochromatic objective and EM-CCD camera (Hamamatsu, C9100-02) equipped with ScanR modular imaging platform (Olympus). ScanR Acquisition software (version 2.2.0.8) was used for microscope

(12) USP7 deubiquitinase stabilizes FAN1 to support DNA crosslink repair and suppress CAG repeat expansionNature CommunicationsMarch 6, 2026Giulio Collotta, Marco Gatti, Irina-Maria Ungureanu, Vanessa van Ackeren, Emilie Rannou, Francesca Vivalda, Diego Gomez Vieito, Keri M. Fishwick, Christine von Aesch, Antonio Porro, et al.cytometry (QIBC) Automated multichannel wide-field microscopy for QIBC was performed using the Olympus ScanR System as described previously74. Images of cell populations were acquired under non-saturating conditions

(13) Modelling G protein-biased agonism using GLP-1 receptor C-terminal mutationsMolecular MetabolismMarch 1, 2026Hanh Duyen Tran, Yiming Zuo, Carissa Wong, Alice Pollard, Steve Bloom, Ben Jonesobjective, Yokogawa CSU-W1 spinning disc unit and Hamamatsu ORCA-Fusion sCMOS camera, controlled by ScanR acquisition software (Evident, UK). 9 FOVs were acquired per well including Z-stacks with 12 planes

(14) Hemizygous loss of helicases promotes genomic instability and cancer developmentScience AdvancesFebruary 20, 2026Karolin Voßgröne, Francesco Favero, Krushanka Kashyap, Francisco G. Rodríguez-González, André V. Olsen, Xin Li, Balca R. Mardin, Joachim Weischenfeldt, Claus S. Sørensenthe secondary antibody at a final concentration of 0.1 μg/ml. Imaging was performed using an Olympus ScanR workstation, and the respective software was used for the analysis. Immunofluorescence statistics All

(15) FANCD2 restrains fork progression and prevents fragility at early origins upon re-replicationNature CommunicationsFebruary 7, 2026Nibal Badra-Fajardo, Elena Karydi, Aleix Bayona-Feliu, Belén Gómez-González, Ourania Preza, Marina Arbi, Argyro Kalogeropoulou, Juha K. Rantala, Stavros Taraviras, Andrés Aguilera, et al.pictures per well were acquired for the analysis of over 1000 cells using a 20x air lens using an Olympus ScanR wide-field microscope equipped with DAPI, FITC, Cy3 and Cy5 filters. Automated image quantification

(16) A plastic EMP1⁺ to LGR5⁺ cell state conversion as a bypass to KRAS-G12D pharmacological inhibition in metastatic colorectal cancerCancer DiscoveryFebruary 6, 2026Alessia Centonze, Adrià-Jaume Roura, Meritxell Novillo-Font, Cristina Giordano, Xavier Hernando-Momblona, Montserrat Llanses, Paula Prats, Marta Sevillano, Débora Cabot, Mireia Novell, et al.correction set at 1.8 in the image control panel. AKTP MTO images were taken using a 1 × 81 Olympus ScanR microscope and analyzed with the RT Xcellence Software (v1.2). In Situ Hybridization – RNAscope Samples

(17) PAF15–PCNA exhaustion governs the strand-specific control of DNA replicationNatureJanuary 28, 2026Gita Chhetri, Sugith Babu Badugu, Narcis-Adrian Petriman, Mikkel Bo Petersen, Aylin Seren Güller, Nora Fajri, Manon Coulée, Ganesha Pandian Pitchai, Jan Novotný, Frederik Tibert Larsen, et al.P36961). QIBC QIBC was performed as previously described2,18,39,59,61. In brief, images were acquired with a ScanR inverted microscope high-content screening station (Olympus) equipped with wide-field optics, a 203,

(18) Identification of Novel Growth Factor Conjugated Nanofibers for Stimulation of Neuronal GrowthMacromolecular BioscienceJanuary 23, 2026Yu‐Liang Tsai, Karla K. Rivera, Nayeong Jeon, Bernd Knöll, Christopher V. Synatschke4°C. 2.12 Quantification and Statistics Plates were scanned with an Olympus IX‐83 microscope using the scanR 3.1 Acquisition Software. Images were analyzed using a neural network designed and provided by Evident

(19) Systemic distribution of tricyclo-DNA antisense oligonucleotide following intratracheal instillation in the mouseNAR Molecular MedicineJanuary 22, 2026Jérémy Laurent, Therese B Deramaudt, Romane Cloix, Valérie Robin, Cyriaque Beley, Luis Garcia, Marcel Bonaywere washed in 1× SSC and PBS. After DAPI staining, sections were coverslipped and imaged using the ScanR high-content screening station (Olympus) and the SP8 confocal microscope (Leica Microsystems). For immunohistochemistry analysis, following

(20) An Inducible BRCA1 Expression System with In Vivo Applicability Uncovers Activity of the Combination of ATR and PARP Inhibitors to Overcome Therapy ResistanceCancers (Basel)January 20, 2026Elsa Irving, Alaide Morcavallo, Jekaterina Vohhodina-Tretjakova, Paul W. G. Wijnhoven, Anna L. Beckett, Michael P. Jacques, Rachel S. Evans, Jennifer I. Moss, Anna D. Staniszewska, Josep V. Formentantibodies and DAPI (Sigma, 1 μg/mL) for 1.5 h (Table 3). Image acquisition was carried out using an Olympus ScanR microscope with a 40× objective to analyse DNA damage-induced foci. Cell cycle distribution was determined

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