OxyFlo™ Single channel blood flow monitor from Oxford Optronix Ltd.

Product Specs
ItemOxyFlo^™ Single channel blood flow monitor
CompanyOxford Optronix Ltd.
Price Get Pricing
Catalog NumberOXYFLO
QuantityEA
Display40 character alphanumeric OLED
PowerAnalog (BNC x2); Digital (USB)
Measuring Range0 to 9999 blood perfusion units (BPU)
Mode of OperationLaser doppler flowmetry
Channels1
Temperature Range10 to 30ºC
TypeSingle-channel blood flow monitor, benchtop
ApplicationsIn vivo tissue blood perfusion monitoring

Specifications/Features

Uncompromised performance in continuous tissue blood perfusion assessment Ideally suited to measurements of changing tissue blood flow in acute experimental models Unrivalled ease-of-use Built-in choice of analogue and digital data outputs

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Oxford Optronix Ltd.

9 & 10 Somerville Court

Trinity Way

Banbury Business Park, Adderbury OX17 3SN

United Kingdom

Phone: +44 (0)1235 821 803

Email: sales@oxford-optronix.com
info@oxford-optronix.com
support@oxford-optronix.com

Company Profile

Website: www.oxford-optronix.com

(1) Oxygen tension regulating nanoformulation for the improved photodynamic therapy of hypoxic tumorsMaterials Today BioApril 1, 2025Yihenew Simegniew Birhan, Chia-Yen Hsu, Hsiu-Ping Yu, Ping-Shan Laithe level of pO2 in mice muscle tissue, normoxic and hypoxic tumor-bearing mice was measured (OxyLite/OxyFlo, Oxford Optronix Ltd.) and a relatively high oxygen level (lower oxygen tension) was observed in muscle tissue

(2) Abnormal skeletal muscle and myocardial vasoreactivity manifests prior to heart failure in a diabetic cardiomyopathy rat modelDiscov Med (Cham)January 6, 2025Sadi Loai, Hai-Ling Margaret ChengMRI were validated with real-time perfusion measurements at endpoint using laser Doppler flowmetry (OxyFlo, Oxford Optronix; Abingdon, UK). A fiber-optic probe (250–450 µm diameter) was secured into the gastrocnemius muscle

(3) The impact of collateral therapeutics on stroke hemodynamics in normotensive and hypertensive rats: a step toward translationFrontiers in NeurologyMarch 21, 2024Marilyn J. Cipolla, Ryan D. Hunt, David S. Liebeskind, Sarah M. Tremblewith TM5441 as described above, except that a combination probe that measured oxygen and blood flow (OxyFlo/OxyLite, Oxford Optronix, United Kingdom) was used to measure cortical CBF in the penumbra and brain

(4) Memantine inhibits cortical spreading depolarization and improves neurovascular function following repetitive traumatic brain injuryScience AdvancesDecember 15, 2023Mark A. MacLean, Jamil H. Muradov, Ryan Greene, Gerben Van Hameren, David B. Clarke, Jens P. Dreier, David O. Okonkwo, Alon Friedman(aCSF) (5). Regional cortical blood flow was measured using laser Doppler flowmetry (Oxford Optronix, OxyFlo, 2000). Intravital cortical microscopy was performed (Axio Zoom V16, Zeiss GmbH and CMOS camera, PCO Edge

(5) Effect of Neck-Deep Immersion in Cool or Thermoneutral Water on Blood Glucose Levels in Individuals With Type 1 DiabetesJournal of the Endocrine SocietyNovember 2, 2023Kristina J Abramoff, Lauren L De Souza, Shane K Maloney, Elizabeth A Davis, Timothy W Jones, Paul A FournierDoppler flowmeter (LDF; Blood Flow Meter, ADInstruments Pty Ltd, Sydney) and a skin surface probe (OxyFlo Probe, Oxford Optronix Ltd., Oxford, UK) [28]. The probe was secured using an adhesive mounting ring

(6) Blood-pool MRI assessment of myocardial microvascular reactivityFrontiers in Cardiovascular MedicineNovember 1, 2023Sadi Loai, Beiping Qiang, Michael A. Laflamme, Hai-Ling Margaret Chengterminal session, animals underwent real-time perfusion measurements using laser Doppler flowmetry (OxyFlo, Oxford Optronix, Abingdon, United Kingdom) to corroborate MRI results. A novel approach was developed

(7) Oxygen-loaded microbubble-mediated sonoperfusion and oxygenation for neuroprotection after ischemic stroke reperfusionBiomaterials researchJuly 6, 2023Ho YJ, Cheng HL, Liao LD, Lin YC, Tsai HC, Yeh CK.murine S/R model, a fiberoptic probe (NX-BF/OFT/E, Oxford Optronics, Oxford, UK) linked to OxyLite and OxyFlo 2000 systems (Oxford Optronix) was non-invasively placed downstream of ACArb (~ 0.5 mm lateral to bregma)

(8) Angiotensin II–Mediated Neuroinflammation in the Hippocampus Contributes to Neuronal Deficits and Cognitive Impairment in Heart Failure RatsHypertensionJune 1, 2023Ferdinand Althammer, Ranjan K. Roy, Matthew K. Kirchner, Elba Campos-Lira, Kathryn E. Whitley, Steven Davis, Juliana Montanez, Hildebrando Candido Ferreira-Neto, Jessica Danh, Rafaela Feresin, et al.a stereotaxic apparatus using an optical fluorescence probe (250 μm tip diameter; OxyLite (pO2) and OxyFlo (CBF) systems; Oxford Optronix) that allows real-time recording of absolute values of these parameters. Assessment

(9) Postoperative Stroke after Spinal Anesthesia and Responses of Carotid or Cerebral Blood Flow and Baroreflex Functionality to Spinal Bupivacaine in RatsBiology (Basel)July 2, 2021Yan-Yuen Poon, Yueh-Wei Liu, Ya-Hui Huang, Samuel H. H. Chan, Ching-Yi Tsaicerebral artery [37]. Real-time microvascular red blood cell perfusion in tissue was processed by an OxyFlo monitor (Oxford Optronix). The laser Doppler signals from the tissue were recorded in blood perfusion

(10) IL-10 Mediated Immunomodulation Limits Subepithelial Fibrosis and Repairs Airway Epithelium in Rejecting Airway AllograftsCellsMay 19, 2021Mohammad Afzal Khan, Ghazi Abdulmalik Ashoor, Talal Shamma, Fatimah Alanazi, Abdullah Altuhami, Shadab Kazmi, Hala Abdalrahman Ahmed, Abdullah Mohammed Assiri, Dieter Clemens Broeringand blood flow (blood perfusion units (BPUs)) in transplants were measured in real-time by OxyLite/OxyFlo combined sensors (model NX-BF/OF/E, Oxford Optronix, Milton, UK) as originally described [41,42]. Transplanted

(11) A novel MRI analysis for assessment of microvascular vasomodulation in low-perfusion skeletal muscleScientific ReportsDecember 1, 2020Eric Zakher, Tameshwar Ganesh, Hai-Ling Margaret Chengmeasurements To validate observations on MRI, real-time laser Doppler perfusion measurements were taken using the OxyFlo (Oxford Optronix Ltd, Oxford, UK) fiber-optic system for all animals. Measurements were in blood perfusion

(12) Hypobaric hypoxia preconditioning protects against hypothalamic neuron apoptosis in heat-exposed rats by reversing hypothalamic overexpression of matrix metalloproteinase-9 and ischemiaInternational Journal of Medical SciencesSeptember 20, 2020Chien-Ming Chao, Chun-Liang Chen, Ko-Chi Niu, Cheng-Hsien Lin, Ling-Yu Tang, Lieh-Sheng Lin, Ching-Ping ChangThis combined probe was used to measure oxygen, temperature, and microvascular blood flow. OxyLite and OxyFlo instruments were used for the measurements. The OxyLite 2000 instrument (Oxford Optronix, Oxford, UK)

(13) Cerebral Blood Flow-Guided Manipulation of Arterial Blood Pressure Attenuates Hippocampal Apoptosis After Asphyxia-Induced Cardiac Arrest in RatsJournal of the American Heart AssociationJuly 7, 2020Wang CH, Chang WT, Huang CH, Tsai MS, Liu SH, Chen WJ.per minute, and an inspired oxygen fraction of 21%. To measure CBF, a stationary laser Doppler probe (OxyFlo™; Oxford‐Optronix, Oxford, UK) was inserted through a small cranial window created over the left hemisphere.

(14) Theta-burst transcranial magnetic stimulation promotes stroke recovery by vascular protection and neovascularizationTheranosticsJanuary 1, 2020Zong X, Li Y, Liu C, Qi W, Han D, Tucker L, Dong Y, Hu S, Yan X, Zhang Q.the stereotaxic frame under isoflurane anesthesia at 6 h, 6 d and 22 d following PT stroke. A laser OxyFlo XP Probe connected to an Oxy-Lab LDF Microvascular Perfusion Monitor (Oxford Optronix Ltd, UK), was

(15) Histone deacetylase activity mediates thermal plasticity in zebrafish (Danio rerio)Scientific ReportsDecember 1, 2019Frank Seebacher, Alec I. M. Simmondsmm wide at the top and 60 mm long), and the peristaltic flow kept the surface of the fish moist. An OxyFlo Needle Probe (MNP110XP, Oxford Optronix Ltd, Milton, Abingdon, UK) was positioned with a stereotaxic

(16) Dose-Dependent Acute Circulatory Fates Elicited by Cadmium Are Mediated by Differential Engagements of Cardiovascular Regulatory Mechanisms in BrainFrontiers in PhysiologyJune 18, 2019Shu-Mi Chen, Suttinee Phuagkhaopong, Chi Fang, Jacqueline C. C. Wu, Ya-Hui Huang, Pornpun Vivithanaporn, Hsun-Hsun Lin, Ching-Yi Tsaimonitor (Oxford Optronix). Real-time microvascular red blood cell perfusion in tissue was processed by an OxyFlo monitor (Oxford Optronix). The laser Doppler signals from the tissue were recorded in blood perfusion

(17) Alterations in regional kidney oxygenation during expansion of extracellular fluid volume in conscious healthy sheepAmerican Journal of Physiology-Regulatory, Integrative and Comparative PhysiologyDecember 1, 2018Yugeesh R. Lankadeva, Roger G. Evans, Junko Kosaka, Lindsea C. Booth, Naoya Iguchi, Rinaldo Bellomo, Clive N. Mayflowmeter (T402/TS420, Transonic Systems), and the fiber optic probes were connected to OxyLite PRO and OxyFlo XL monitors (Oxford Optronix) to provide measurements of renal cortical and medullary laser-Doppler

(18) Renal autoregulation in experimental septic shock and its response to vasopressin and norepinephrine administrationJournal of Applied PhysiologyDecember 1, 2018Emiel Hendrik Post, Fuhong Su, Cláudia Righy Shinotsuka, Fabio Silvio Taccone, Jacques Creteur, Daniel De Backer, Jean-Louis VincentFinally, the kidney fascia was carefully punctured twice to enable insertion of laser Doppler probes (OxyFlo; Oxford Optronix, Oxford, UK) in the renal cortex and medulla. Hemodynamic and general monitoring. Cardiac

(19) CD34− human placenta-derived mesenchymal stem cells protect against heat stroke mortality in ratsOncotargetJanuary 5, 2018Willie Lin, Yogi Chang-Yo Hsuan, Yu-Chin Su, Cheng-Hsien Lin, Mao-Tsun Lin, Zi-Hao Chen, Ching-Ping Chang, Kao-Chang Lina 100-mm diameter thermocouple and two 230 mm fibers. Measurements were acquired using OxyLite and OxyFlo instruments (Oxford optronix, Oxford, UK). The OxyLite 2000 is a two-channel device for measuring temperatures,

(20) Imatinib increases oxygen delivery in extracellular matrix-rich but not in matrix-poor experimental carcinomaJournal of Translational MedicineDecember 1, 2017Mikhail Burmakin, Tijs van Wieringen, P. Olof Olsson, Linda Stuhr, Aive Åhgren, Carl-Henrik Heldin, Rolf K. Reed, Kristofer Rubin, Carina HellbergpO2 and blood flow were measured simultaneously utilizing two-channel probes using OxyLite 2000 and OxyFlo instruments, respectively (Oxford Optronix, Oxford, UK). Four probes were inserted at different sites

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OxyFlo^™ Single channel blood flow monitor

OxyFlo^™ Single channel blood flow monitor from Oxford Optronix Ltd.

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Specifications/Features

Oxford Optronix Ltd.

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OxyFlo^™ Single channel blood flow monitor from Oxford Optronix Ltd.

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