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Maxwell® RSC 48 Instrument
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Maxwell® RSC 48 Instrument
Maxwell® RSC 48 Instrument
Maxwell® RSC 48 Instrument from Promega
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Citations:
(160)
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Maxwell® RSC 48 Instrument
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Description
The Maxwell RSC 48 Instrument is a platform for automated purification of nucleic acid from a range of sample types. Purification methods use sample lysis and binding to paramagnetic particles as the primary separation principle.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell® RSC 48 Instrument
Company
Promega
Price
Supplier Page
Catalog Number
AS8500
Quantity
EA
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (160)
(1)
Natural senolytic activity of Rhodiola rosea extract alleviates age-associated phenotypes via paraptosis
iScience
May 15, 2026
Ryo Furuuchi, Yohko Yoshida, Goro Katsuumi, Takaaki Furihata, Yusuke Joki, Chieh-Lun Hsiao, Masayoshi Suda, Hana Saito, Tamano Kumazaki, Hidefumi Makabe,
et al.
was extracted from tissue and cell samples using either QIAzol Lysis Reagent (
QIAGEN
,
79306
) or the
Maxwell RSC 48 Instrument
(
Promega
) in combination with the
Maxwell RSC simplyRNA Tissue Kit
(
Promega
,
AS1340
), according to the
(2)
Rapid Preparation of Electrocompetent Listeria monocytogenes and Enhancement of Transformation Efficiency with cAMP Supplementation☆
Journal of Food Protection
May 1, 2026
A.V. Gutiérrez, N. Som, E. Smith, M. Diaz, M. Matthews, R.A. Kingsley, M. Gilmour
for short-read
sequencing
was extracted from 800 µL of overnight culture in BHI using the automated
Maxwell® RSC 48 instrument
and the Maxwell® RSC
Cultured Cells
DNA (
Promega
; Madison, WI, USA) kit following the manufacturer’s
(3)
Adapting Clinical Chemistry Plasma as a Source for Liquid Biopsies
eLife
May 1, 2026
Spencer C Ding, Jingru Yu, Tiepeng Liao, Lauren S Ahmann, Yvette Y Yao, Chandler Ho, Linlin Wang, Benjamin A Pinsky, Wei Gu
described (Gu et al., 2021). DNA extraction cfDNA was extracted from 0.5 to 1 mL of plasma using the
Maxwell RSC 48 instrument
(
Promega
) with the
Maxwell RSC ccfDNA Plasma Kit
(
AS1480
), following the manufacturer’s instructions.
(4)
Mapping genomic heterogeneity in paediatric and adolescent-young adult sarcomas: insights from the Italian SAR-GEN2016 and SAR-GEN_ITA prospective multicenter trials
Cancer Research Communications
April 1, 2026
Elisa Tirtei, Valeria Difilippo, Federico Divincenzo, Sebastian Dorin. Asaftei, Nicola Ratto, Raimondo Piana, Pietro Pellegrino, Alessandra Linari, Mauro Papotti, Katia Mareschi,
et al.
2-μm-thick FFPE sections (8–10 sections per sample) using
Maxwell RSC DNA FFPE Kit
(
Promega Corporation
) on
Maxwell RSC 48 Instrument
(
Promega Corporation
) following the manufacturer’s protocol. DNA from peripheral blood samples was used
(5)
Intranasal immunization with live-attenuated RSV-vectored SARS-CoV-2 vaccines elicits antigen-specific systemic and mucosal immunity and protects against viral challenge and natural infection
bioRxiv
March 31, 2026
Davide Botta, Michael D. Schultz, Aaron Silva-Sanchez, Davies Kalange, Jobaida Akther, Fen Zhou, Jennifer L. Tipper, Guang Yang, Levi T. Schaefers, Courtney A. Barkley,
et al.
Maxwell® RSC Viral Total Nucleic Acid Purification Kit
(
Promega
), vortexed, and incubated at 56 °C for 10 min. RNA was extracted using the
Maxwell® RSC 48 Instrument
(
Promega
) according to manufacturer’s instructions. Quantitative
RT-PCR
was performed on a QuantStudio™
(6)
Evaluating long-term stool preservation methods for maximizing the recovery of viable human fecal microbiota
Gut Microbes Reports
March 30, 2026
Youzheng Teo, Anton Lavrinienko, Diana Albertos Torres, Paul Tetteh Asare, Antonia Ruder, Maria Gloria Dominguez-Bello, Adrian Egli, Nicholas A. Bokulich, Pascale Vonaesch
RSC PureFood GMO and Authentication Kit (
Promega
,
AS1600
) and a
Maxwell RSC 48 instrument
(
Promega
,
AS8500
). The bacterial suspensions were thawed, and 200 µL of the suspension was transferred into a PowerBead
(7)
Next‐Generation Short‐Read Sequencing Reveals Impacts on Major Histocompatibility Complex Diversity Resulting From Differences in Captive Rhesus Macaque ( Macaca Mulatta ) Colony Expansion Strategies
American Journal of Primatology
February 27, 2026
Sreetharan Kanthaswamy, Roger W. Wiseman, Miranda R. Stauss, Max C. Ertl, Divy K. Patel, David G. Smith, Melween I. Martínez, Elizabeth Maldonado, Carlos A. Sariol
isolated from barcoded blood tubes using Maxwell® Buffy Coat DNA Kits with a Maxprep® Liquid Handler and
Maxwell® RSC 48 instrument
(
Promega
, Madison, WI). Barcoding and robotic liquid handling helped prevent sample mix-ups. Purified
(8)
Adapting Clinical Chemistry Plasma as a Source for Liquid Biopsies
medRxiv
February 27, 2026
Spencer C. Ding, Jingru Yu, Tiepeng Liao, Lauren S. Ahmann, Yvette Y. Yao, Chandler Ho, Linlin Wang, Benjamin A. Pinsky, Wei Gu
described(26). DNA extraction Cell-free DNA (cfDNA) was extracted from 0.5 to 1 mL of plasma using the
Maxwell RSC 48 instrument
(
Promega
) with the
Maxwell RSC ccfDNA Plasma Kit
(
AS1480
), following the manufacturer’s instructions.
(9)
Immunopeptidomics of cutaneous leishmaniasis patients reveals the natural antigenic landscape
Frontiers in Immunology
February 20, 2026
Nicky de Vrij, Elise Pepermans, Louise Laurijssen, Thao-Thy Pham, Lauren Thijs, Kurt Boonen, Kadrie Ramadan, Ilse Maes, Yetemwork Aleka, Mekibib Kassa,
et al.
the
mass spectrometry
-based immunopeptidomics
assay
(Cohort 1 study samples) (Figure 1), using the
Maxwell® RSC 48 instrument
(
Promega
, Wisconsin, U.S.A.) with the
Maxwell® RSC Whole Blood DNA kit
(
Promega
, Wisconsin, U.S.A.)
(10)
Development of a non-invasive diagnostic method for pathogenic RNA viruses using sebum wiped from the cat’s body surface
Scientific Reports
February 18, 2026
Yuri V Fukushima, Namiko Saito, Hirohisa Mekata, Akatsuki Saito
RNA from cat BSLs was processed using the
Maxwell® RSC 48 Instrument
(
Promega
, Madison, WI, USA; Cat#
AS8500
) in combination with the
Maxwell® RSC miRNA Plasma and Serum Kit
(
Promega
; Cat#
AS1680
), according to
(11)
Dynamics of natural and pharmacologic control of an SIV variant with an envelope trafficking defect
J Exp Med
February 2, 2026
Kyle Rhodehouse, Carolin Zitzmann, Meghana Ravi, Ciara Armstrong, Milica Moskovljevic, Hannah P. Moore, Courtney Schill, Emily J. Fray, Mithra R. Kumar, Toni Penney,
et al.
(Del Prete et al., 2016). Animal genotyping Genomic DNA was isolated from whole blood samples with a
Maxwell RSC 48 instrument
using a
Maxwell RSC Buffy Coat DNA kit
according to the manufacturer’s protocol (
Promega
). Amplicons
(12)
The COMFORTage project: study protocol for the integration of multiple sources towards personalised preventions at Ace Alzheimer Center Barcelona
Frontiers in Digital Health
January 26, 2026
Sergi Valero, Andrea Miguel, Josep Blazquez-Folch, Berta Calm, Montserrat Alegret, Ariadna Solivar, George Manias, Athos Antoniades, Nelina Angelova, Despina Psimaris,
et al.
research purposes (42). 2.4.6
Genotyping
Genomic DNA is extracted from buffy coat samples using the
Maxwell RSC 48 instrument
(
Promega
) with the
AS1540
DNA extraction kit, ensuring high-quality samples for genetic analysis, and
(13)
Tracking Antimicrobial Resistance in Salmonella via Poultry Supply Chains, Human Clinical Samples, and Environmental Reservoirs
Foods
January 23, 2026
Diana M. Álvarez-Espejo, Diego Fredes-García, Constanza Díaz-Gavidia, Sebastián Gutiérrez, Rocio Barron-Montenegro, Francisca P. Álvarez, Rodrigo Constenla-Albornoz, Vivien Cadet-Arenas, Angélica Reyes-Jara, Jorge Olivares-Pacheco,
et al.
S1A–C). Genomic DNA from poultry meat isolates was extracted using the
Cultured Cells
DNA Kit on a
Maxwell RSC-48 Instrument
(
Promega
, Madison, WI, USA). Libraries were constructed with the Illumina DNA Prep kit (Illumina, San
(14)
The Regulation of Oxidative Stress Is a Conserved Response to RNA Virus Infection in Fish
Antioxidants (Basel)
January 12, 2026
Alejandro Romero, Patricia Pereiro, Antonio Figueras, Beatriz Novoa
extracted using the SimplyRNA Tissue Kit (Promega Biotech Iberica, Madrid, Spain) in the automated
Maxwell RSC 48 Instrument
(
Promega
Biotech Iberica, Madrid, Spain), following the manufacturer’s protocol. RNA concentration was
(15)
The structure and allelic diversity of the self-incompatibility locus (S-locus) in diploid potatoes inferred from genome sequences and transcriptome data from styles and pollen
Plant Genome
December 22, 2025
Mercedes Ames, Dennis Halterman, Paul C. Bethke
nitrogen. RNA extraction was done using the
Maxwell RSC Plant RNA Kit
(
Promega Corporation
) and the
Maxwell RSC 48 instrument
(
Promega
). Extracted RNA was submitted to the
Gene Expression
Center at the University of Wisconsin‐Madison
(16)
Exploring transmission dynamics in epidemiologically linked pulmonary tuberculosis cases and household contacts: a WGS-based investigation
BMC Genomics
December 18, 2025
Getachew Seid, Andrea Maurizio Cabibbe, Betselot Zerihun, Ayinalem Alemu, Getu Diriba, Gemechu Tadesse, Wilber Sabiiti, Kiarash Moghaddasi, Ilaria Iannucci, Daniela Maria Cirillo,
et al.
extracted and purified using the
Maxwell RSC Pathogen Total Nucleic Acid Kit
(
Promega
)
procedure
on the
Maxwell RSC 48 Instrument
according to the manufacturer’s instructions [20]. DNA libraries were generated using the Illumina DNA
(17)
Campylobacter jejuni stimulates a robust cytokine response in the cecal tonsil following a repeated challenge infection model
Poultry Science
December 1, 2025
Christina L. Swaggerty, Alejandra V. Velilla, Kenneth J. Genovese, J. Allen Byrd, Michael H. Kogut
Scientific). Total RNA was extracted from the homogenate using the
Maxwell® RSC SimplyRNA Tissue Kit
on the
Maxwell® RSC 48 instrument
according to the manufacturer’s instructions (
Promega
Corp., Madison, WI). Briefly, Thioglycerol/Homogenization
(18)
Infection Dynamics and Host Biomarker Identification for Spotty Liver Disease in Chickens
Vet Sci
November 29, 2025
Helen James, Emily Gan, Robert J. Moore, Daniel M. Andrews, Thi Thu Hao Van
Control Approximately 20–30 mg of liver tissue was homogenised, and total RNA was extracted using the
Maxwell® RSC 48 Instrument
with the
Maxwell® RSC miRNA Tissue Kit
(
Promega
, Madison, WI, USA) according to the manufacturer’s instructions.
(19)
Germline Variant Call Accuracy in Whole Genome Sequence Data from Canine Formalin-Fixed Paraffin-Embedded Tissue Samples
Genes (Basel)
November 11, 2025
Vidhya Jagannathan, Tosso Leeb
derived from three 2-month-old male
dogs
(
dogs
#1–3) using the Maxwell RSC Whole Blood Kit and the
Maxwell RSC 48 instrument
(
Promega
, Dübendorf, Switzerland). The size distribution of the DNA fragments was evaluated on a Femto
(20)
The histone variant H3.14 is an early player in the abiotic stress response of Arabidopsis
Developmental Cell
November 3, 2025
Rocío Nunez-Vazquez, Sofía Madeira, Laura Rodríguez-Casillas, Diego Gomez-Martinez, Bénédicte Desvoyes, Crisanto Gutierrez
RNA,
Promega
,https://www.promega.es/en/products/
lab-automation
/automated-dna-rna-extraction-
purification
-maxwell/
maxwell-rsc-48-instrument
/?tabset0=0&cs=y BioruptorPico,Diagenode,https://www.diagenode.com/en/p/bioruptorpico2 AmershamTM Imager
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