Mouse Motor Neuron-Like Hybrid Cell Line (NSC-34) from CEDARLANE

Product Specs
ItemMouse Motor Neuron-Like Hybrid Cell Line (NSC-34)
CompanyCEDARLANE
Price Supplier Page View Company Product Page
Catalog NumberCLU140
Quantity1 vial
Cell LineNSC-34
Cell Type (standardized)Neural Stem Cells
Tissue (standardized)Brain
SpeciesMouse
TissueSpinal Cord
Cell TypeMotor Neurons
Validated Species ReactivityMouse (Ms)

Specifications/Features

Cell Line:
(NSC-34)

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CEDARLANE

4410 Paletta Court

Burlington, Ontario L7L 5R2

Canada

Phone: +1 (289) 288-0001
Toll Free (North America): +1 (800) 268-5058
Fax: +1 (289) 288-0020

Email: general@cedarlanelabs.com

Company Profile

Website: http://www.cedarlanelabs.com/

(1) ENDOU-1-induced cytoplasmic HnRNPA3 recognizes m6A methylation on the upstream reading frame of human CHOP transcripts to achieve maximal CHOP translationCellular and Molecular Life SciencesMarch 28, 2026Hung-Chieh Lee, Yi-Hsin Huang, Chi-Cheng Hsieh, Yi-Nan Ke, Huai-Jen TsaiNSC-34 cells were obtained from Cedarlane Laboratories (Cedarlane, Burlington, ON, Canada, Cat. no. CLU140). HepG2 cells were provided by Prof. Jin-Chuan Sheu, Liver Disease Prevention and Treatment Research

(2) Development of a PTEN-siRNA activated scaffold to promote axonal regrowth following spinal cord injuryBioact MaterFebruary 9, 2026Tara K. McGuire, Martyna Stasiewicz, Cian O'Connor, Ian Woods, Jack Maughan, Marko Dobricic, Giulio Brunetti, James E. Dixon, Adrian G. Dervan, Fergal J. O'Brien1 μg siRNA (266 ng/μL)). NSC34 neuronal culture and transfections: NSC34 neurons (Cedarlane Cat No. CLU140), a hybrid cell line produced by the fusion of motor neuron enriched embryonic mouse spinal cord cells

(3) Munc13-1 restoration mitigates presynaptic pathology in spinal muscular atrophyNature communicationsSeptember 30, 2025Moradi M, Weingart J, Deng C, Nasouti M, Briese M, Jablonka S, Sauer M, Sendtner M.ultracentrifugation at 60–72 h post-transfection. Virus titer was determined in NSC34 cells (Cedarlane, cat. no. CLU140), using standard methods with serial dilutions. Generation of Cre/loxP conditional Munc13-1 rescue

(4) Biomimetic Scaffolds Enhance iPSC Astrocyte Progenitor Angiogenic, Immunomodulatory, and Neurotrophic Capacity in a Stiffness and Matrix‐Dependent Manner for Spinal Cord Repair ApplicationsAdvanced Healthcare MaterialsMay 19, 2025Cian O'Connor, Ian Woods, Sarah F. McComish, Sean Kerr, Matthew McGrath, Juan Carlos Palomeque Chávez, Jack Maughan, Tara McGuire, Maeve A. Caldwell, Adrian Dervan, et al.different neuronal models to investigate changes in neurite length. NSC‐34 mouse motor neuron cells (CLU140, Cedarlane Labs, Canada) were seeded at 5 × 103 cells on coverslips precoated with poly‐l‐lysine (10

(5) Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogenseLifeDecember 18, 2024Vera Vollenweider, Karoline Rehm, Clara Chepkirui, Manuela Pérez-Berlanga, Magdalini Polymenidou, Jörn Piel, Laurent Bigler, Rolf KümmerliR78007, authenticated) and mouse motor neuron-like neuroblastoma-spinal cord hybrid (NSC-34; Cedarlane CLU140, authenticated) cells to the crude extract of the three most potent pyoverdines (3A06, 3G07, s3b09).

(6) The Impact of the Molecular Weight of Degradation Products with Silicon from Porous Chitosan-Siloxane Hybrids on Neuronal Cell BehaviorPolymers (Basel)August 1, 2023Yuki Shirosaki, Federica Fregnan, Luisa Muratori, Saki Yasutomi, Stefano Geuna, Stefania Raimondoexpress the value. 2.2.5. NSC-34 Cell Differentiation Mouse motor neuron-like cells, NSC-34 (Cedarlane, CLU140) [25], were cultured at 37 °C in a humidified atmosphere of 5% CO2 and seeded at an initial density

(7) Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of HnrnprNature communicationsJuly 12, 2023Salehi S, Zare A, Prezza G, Bader J, Schneider C, Fischer U, Meissner F, Mann M, Briese M, Sendtner M.applied at 20 ng/ml only to the axonal compartment. Cell lines NSC-34 cells (Cedarlane, cat. no. CLU140) and HEK293TN cells (System Biosciences, cat. no. LV900A-1) were grown in high glucose Dulbecco’s modified

(8) Signatures in in vitro infection of NSC-34 mouse neurons and their cell nucleus with Rickettsia helveticaBMC MicrobiologyApril 21, 2023Lena Kask, Carl Påhlson, Karin Staxäng, Kenneth Nilssonand 5% CO2 as previously described [32, 46]. The mouse motor neuron cell line NSC-34 cells (Cat. no. CLU140: Cedarlane, Burlington, Canada) is a hybrid cell line, produced by fusion of motor neuron enriched,

(9) Bile Acids Induce Neurite Outgrowth in Nsc-34 Cells via TGR5 and a Distinct Transcriptional ProfilePharmaceuticals (Basel)January 24, 2023Hayley D. Ackerman, Glenn S. Gerhardtreatment of ALS [9]. 4. Materials and Methods 4.1. Cells NSC-34 cells (Cedarlane catalog number CLU140) were used as a motor neuron cell line model [20,21]. Cells were maintained in Dulbecco’s modified Eagle’s

(10) Autophagy regulates neuronal excitability by controlling cAMP/protein kinase A signaling at the synapseThe EMBO journalNovember 17, 2022Overhoff M, Tellkamp F, Hess S, Tolve M, Tutas J, Faerfers M, Ickert L, Mohammadi M, De Bruyckere E, Kallergi E, et al.Inhibitor (ThermoScientific) using a Wheaton Potter‐Elvehjem Tissue Grinder. Primary neurons, and NSC34 (CLU140, Cedarlane, provided by Prof. B. Wirth) cells were harvested in RIPA buffer containing Protease Inhibitor

(11) Active Ribosome Profiling With RiboLaceSSRN Electronic JournalApril 2, 2022Massimiliano Clamer et al.25 Gencode https://www.gencodegenes.org/ releases/25.html ATCC HTB-22 Experimental Models: Cell Lines MCF7 ATCC NSC34 CEDARLANE CLU140 HeLa N/A N/A HEK293 N/A N/A University of Edinburgh, Tom Gillingwater Lab N/A Experimental Models

(12) Interaction of 7SK with the Smn complex modulates snRNP productionNature communicationsFebruary 24, 2021Ji C, Bader J, Ramanathan P, Hennlein L, Meissner F, Jablonka S, Mann M, Fischer U, Sendtner M, Briese M.h prior to harvesting. NSC-34, HEK293TN, and HeLa cell culture NSC-34 cells (Cedarlane, cat. no. CLU140), HEK293TN cells (System Biosciences, cat. no. LV900A-1) and HeLa cells (Leibniz Institute DSMZ-German

(13) The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory responseJournal of neuroinflammationOctober 14, 2020Lee S, Kim S, Kang HY, Lim HR, Kwon Y, Jo M, Jeon YM, Kim SR, Kim K, Ha CM, et al.CMFDA-positive cells is represented as a percentage of the control. NSC-34 cell culture NSC-34 cells (cat. no. CLU140; Cedarlane) are well-characterized lower motor neuron-like cells generated by the fusion of embryonic

(14) A second open reading frame in human enterovirus determines viral replication in intestinal epithelial cellsNature communicationsSeptember 6, 2019Guo H, Li Y, Liu G, Jiang Y, Shen S, Bi R, Huang H, Cheng T, Wang C, Wei W.(ATCC, HB-8065), A549 (ATCC, CRM-CCL-185), and NSC-34 mouse motor neuron cells (Cedarlane Laboratories, CLU140) were cultured in Dulbecco’s Modified Eagle’s Medium supplemented with 10% FBS and penicillin/streptomycin

(15) NSC ‐34 motor neuron‐like cells are sensitized to ferroptosis upon differentiationFEBS Open BioApril 1, 2019Alejandra M. Martinez, Jovan Mirkovic, Zofia A. Stanisz, Fahmida S. Patwari, Wan Seok Yangmethods Cell culture NSC‐34 cells were purchased from Cedarlane (Burlington, NC, USA) (cat. no. CLU140) and maintained in DMEM supplemented with 10% fetal bovine serum (FBS) and penicillin and streptomycin

(16) Functional Genomics and Immunologic Tools: The Impact of Viral and Host Genetic Variations on the Outcome of Zika Virus InfectionVirusesAugust 11, 2018Sang-Im Yun, Byung-Hak Song, Jordan C. Frank, Justin G. Julander, Aaron L. Olsen, Irina A. Polejaeva, Christopher J. Davies, Kenneth L. White, Young-Min LeeCO2 ATCC (CRL-1573) Charles M. Rice, RU ATCC (CRL-2266) ATCC (SCRC-1008) ATCC (CRL-1658) Cedarlane (CLU140) ATCC (WHO-Vero) ATCC (CRL-1390) ATCC (CCL-22) ATCC (CRL-1746) Irina A. Polejaeva, USU Irina A. Polejaeva, USU ATCC (CCL-57) ATCC (CCL-34) ATCC (CCL-94) Sung-June

(17) Selected gene profiles of stressed NSC-34 cells and rat spinal cord following peripheral nerve reconstruction and minocycline treatmentExperimental and therapeutic medicineMay 1, 2016Keilhoff G, Lucas B, Uhde K, Fansa H.Plan‑Neofluar objective (20/0.5). Cell culture model NSC‑34 cell line culture. NSC‑34 cells (cat. no. CLU140; Cedarlane, Burlington, Canada) were stored at ‑80˚C in cryo tubes. In preparation for experiments,

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Mouse Motor Neuron-Like Hybrid Cell Line (NSC-34) from CEDARLANE

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Mouse Motor Neuron-Like Hybrid Cell Line (NSC-34) from CEDARLANE

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