LCMS-8045RX Triple Quadrupole LC/MS/MS Mass Spectrometer from Shimadzu

Product Specs
ItemLCMS-8045RX Triple Quadrupole LC/MS/MS Mass Spectrometer
CompanyShimadzu
Price Get Pricing Get Quote for this Product
Catalog NumberLCMS-8045RX
QuantityEA
Mass RangeInquire
Ionization MethodESI, APCI, Dual Ionization
ResolutionInquire

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Shimadzu

7102 Riverwood Drive

Columbia, Maryland

United States

Phone: 1-800-477-1227
1-800-477-1227
1-410-381-1222

Company Profile

Website: https://www.ssi.shimadzu.com/

(1) Morphological and hormonal diversity in rose (Rosa hybrida L.) and potato (Solanum tuberosum L.) Ri genotypes: A comparative studyPLoS OneApril 15, 2026Philipp Rüter, Tim Thomsen, Jarosław Tyburski, Piotr Waligórski, Ewa Surówka, Jacek Kęsy, Natalia Mucha, Manh Hung Doan, Traud Winkelmann, Thomas Debenerindependent laboratories, which used either a Nexera XR UHPLC (Shimadzu, Kyoto, Japan) coupled to an LCMS-8045 (Shimadzu, Kyoto, Japan) or an Agilent 1260 HPLC system coupled to an Agilent 6410 Triple Quadrupole

(2) Multiscale-Aware Graph Embedding Approach Uncovers LC-61, a Potent Anti- Leishmania infantum CompoundJournal of Chemical Information and ModelingApril 13, 2026Vinícius Alexandre Fiaia Costa, Alexandra Maria dos Santos Carvalho, Rafael Consolin Chelucci, Felipe da Silva Mendonça de Melo, Gustavo Santos Sandes Felizardo, Clarissa Alves Carneiro Bernardes, Holli-Joi Martin, Rodolpho de Campos Braga, Sébastien Charneau, Eugene N. Muratov, et al.separation was carried out on a Prominence UFLC system (Shimadzu Corporation, Kyoto, Japan), connected to an LCMS-8045 triple quadrupole mass spectrometer (Shimadzu Corporation, Kyoto, Japan) with an electrospray ionization. 4.6.6.1

(3) Revealing regional markers of sauce aroma baijiu in the Chishui River basin: Integrating multi-detection technologies with molecular sensory science and chemometricsFood Chem XApril 3, 2026Long Ma, Tingyao Tu, Mansi Niu, Yuqin Tong, Xingrong Zhao, Junjie Jia, Lei Zheng, Rongkun Tu, Songtao Wang, Suyi Zhang, et al.92–94 in Table S2) and sixteen pyrazines (compounds 127–142 in Table S2) were analyzed using a Shimadzu LCMS–8045 triple quadrupole mass spectrometer. Higher fatty acids were separated on a Waters ACQUITY BEH C18 column

(4) SIRT1 mediates brain metabolic and developmental consequences of methionine synthase deficiency in inborn errors of cobalamin metabolismCell Reports MedicineMarch 17, 2026Karim Matmat, Ziad Hassan, Grégory Pourié, Yaser Atlasi, Snehaa Vivienne Seal, Manon Jeandel, Carole Arnold, Sachin Luharia, Rémy Umoret, Ramia Safar, et al.4-fold volume of a 0.1% formic acid solution. Analytical procedures were conducted using the Shimadzu LCMS 8045 ESI Triple Quadrupole system (Kyoto, Japan). Data analysis was performed using Insight software version

(5) Metabolomics reveals early pregnancy serum metabolic changes and predictive biomarkers in gestational diabetes mellitusNutrition & MetabolismMarch 14, 2026Feng Wang, Xiaodie Li, Xue Gao, Jinping Liang, Xuemei Guo, Jingzhong Ou, Ya Yuan, Chuchu Zhao, Ting Zhang, Juan Daistandard. Liquid chromatography-triple quadrupole tandem mass spectrometry (Shimadzu LC-20AD, Shimadzu LCMS-8045, Kyoto, Japan) was employed. The chromatographic separation was achieved using a Shim-pack C18 column

(6) IFNγ-associated immune-metabolic remodeling is linked to serotonin-kynurenine imbalance and cortical vulnerability in lupus-prone miceFront ImmunolMarch 5, 2026Karim Matmat, Rosa-Maria Guéant-Rodriguez, Emmanuel Darcq, Okan Baspinar, Jean-Marc Alberto, Jean-Louis Guéant, Ayikoé-Guy Mensah-Nyagan, Hélène Jeltsch-Daviddiluted fourfold with 0.1% formic acid solution. Metabolite quantification was performed on a Shimadzu LCMS-8045 electrospray ionization triple quadrupole system (Shimadzu, Kyoto, Japan). Data acquisition and processing

(7) PROTAC-Mediated Degradation of mHTT Aggregates Attenuates Neurotoxicity in Cellular and R6/2 Mouse Models of Huntington’s DiseaseJournal of the American Chemical SocietyMarch 4, 2026Po-Chao Lu, Yung-An Huang, Niaz Wali, Mei-Chun Tseng, Ruei-Yu He, Yijuang Chern, Tzu-Tang Wei, Jiun-Jie Shie, Joseph Jen-Tse Huangvarious concentrations from 1 to 50 ppb. LC–MS/MS Analysis The LC–MS/MS analysis was conducted using an LCMS-8045 triple quadrupole mass spectrometer (Shimadzu, Kyoto, Japan). Chromatographic separation was achieved

(8) Pimenta racemosa extract ameliorates chemically induced ulcerative colitis in rats by suppressing inflammation and oxidative stressInflammopharmacologyFebruary 14, 2026Haitham A. Ibrahim, Fathia S. Elshaarawy, Mohamed I. S. Abd-elhady, Wafaa Hamdy, Merhan E. Ali, Asmaa A. Ahmed, Elsayed K. El-Sayedtetramethylsilane (TMS) as an internal standard. LC/MS analysis was performed using an LC–MS/MS system (Nexera with LCMS-8045, Shimadzu Corporation, Kyoto, Japan)—HPLC (Nexera LC-30AD) equipped with an autosampler (SIL-30AC),

(9) Marine Streptomyces-Derived Lipids Inhibit SARS-CoV-2 3CLpro Through In Vitro and Predicted Multi-Site Binding MechanismsPharmaceuticals (Basel)February 10, 2026Doralyn S. Dalisay, Jomari C. Mateo, Jade Joshua R. Teodosio, Leighiara S. de Guzman, Neaven Bon Joy M. Marcial, Dion Paul C. Caspe, Lex Aliko P. Balida, Jamia Azdina Jamalto create a 100 ng/µL solution. The working solutions were injected into the LCMS system (Shimadzu LCMS 8045®, Kyoto, Japan) at 3 µL (300 ng). A Phenomenex Synergi® (Torrance, CA, USA) C18 column (4 µm, 80 Å,

(10) Early-Stage Growth Restriction of Hymenoscyphus fraxineus on Tolerant Fraxinus excelsior Is Associated with Constitutive Chemical DefensesMicroorganismsFebruary 6, 2026Akira Hattori, Shunsuke Masuo, Yasuhiro Ishiga, Yutaka Tamai, Yuichi Yamaoka, Izumi OkaneChromatographic Peak Identification Esculetin, fraxetin, and scopoletin were measured by using the LC–ESI–MS/MS (LCMS-8045; Shimadzu, Kyoto, Japan) under the following conditions: capillary voltage, 4.5 kV; desolvation line,

(11) Editorial of Topic Issue “Chromatography–Mass Spectrometry Analysis in Biomedical Research and Clinical Laboratory”MoleculesJanuary 30, 2026Andreas Tsakalof, Constantinos K. Zacharisamino acids were quantified by liquid chromatography coupled with a triple quadrupole mass spectrometer LCMS-8045 (Shimadzu, Kyoto, Japan). Amino acids homeostasis was also investigated by Posma et al. in patient with

(12) Glutamine enhances endothelial cell survival and vasodilation by increasing glutathione to reduce oxidative stressPhysiological ReportsJanuary 21, 2026Marzyeh Kheradmand, Gurneet Sangha, Claire M. Sissons, Michael Sun, Xinyao Zhou, Lauren V. Smith, Meagan Bauer, Chengpeng Chen, Alisa Morss Clyneused to establish a standard curve. 3 μL of each sample was analyzed in duplicate using a Shimadzu LCMS‐8045 CL Triple Quad LC–MS/MS with an attached Nexera HPLC/UHPLC Pump (LC‐20AD XR) and a Luna Omega Polar

(13) Cardenolide‐Engineered Extracellular Vesicles Augment Drug Uptake and Cytotoxicity in Non‐small Cell Lung Cancer CellsSmall MethodsJanuary 14, 2026Maja Dorfner, Anika Mifka, Rodrigo Maia de Pádua, Izabella Thaís da Silva, Iara Zanella Guterres, Lorenzo Sana, Gregor Fuhrmann, Jennifer MunkertIntracellular Doxorubicin 4.15.1 LC‐MS/MS Setup LC MS/MS measurements were performed on a Shimadzu system (LCMS‐8045) equipped with an autosampler (SIL‐40C XR) coupled to a quadrupole mass spectrometer with an electrospray

(14) Identification of a novel ACADSB variant for the presymptomatic diagnosis of 2-Methylbutyryl-CoA dehydrogenase deficiency through newborn screening in IranOrphanet Journal of Rare DiseasesJanuary 12, 2026Maryam Nasri, Nejat Mahdieh, Farzaneh Abbasi, Reihaneh Mohsenipour, Saeideh Abdolahpouranalysis. Targeted metabolomic profiling of amino acids and acylcarnitines was performed using a Shimadzu LCMS-8045 triple quadrupole LC/MS system. A validated commercial kit for newborn screening, the MassChrom® Newborn Screening

(15) Coptidis Rhizoma extract mitigates sleep deprivation-induced cognitive impairment and neurodegeneration: Insights into hormonal, glymphatic, and molecular mechanismsJournal of Traditional and Complementary MedicineJanuary 10, 2026Chih-Yuan Yang, Yea-Hwey Wang, Kuo-Tong Liou, Shuo-En Hsu, Cher-Chia Chang, Yen-Yu Chen, Terry B.J. Kuo, Hung-Tse Huang, I-Wen Lo, Chia-Ching Liaw, et al.confirmed by the reference compounds and mass data using a Shimadzu Nexera-i LC-40D xsi system with an LCMS-8045 mass spectrometer (Table 1). 2.3 Animal grouping and induction of sleep deprivation (SD) in mouse model Male

(16) Invasive Goldenrod (Solidago gigantea Aiton) as a Source of Natural Bioactive Antimicrobial, Insecticidal, and Allelopathic CompoundsMoleculesDecember 29, 2025Elżbieta Gębarowska, Jacek Łyczko, Anna Kmieć, Paulina Bączek, Kamila Twardowska, Bogdan Stępieńluteolin in the sample was determined with an earlier test). The analyses were run in triplicate on an LCMS-8045 instrument with an ESI-type ion source (Shimadzu, Kyoto, Japan) equipped with a Kinetex 2.6u C18 100A

(17) Identification of Aspergillus terreus and Aspergillus pseudonomiae as causative agents of aspergillosis in endangered Okinawa RailsFront Vet SciDecember 22, 2025Sofia Marisel Rivelli Zea, Yumiko Nakaya, Hiroki Takahashi, Takashi Nagamine, Takashi Yaguchi, Takahito ToyotomeJapan) was used. The column temperature was maintained at 40 °C, and the injection volume was 10 μL. LCMS-8045 (Shimadzu Corporation, Kyoto, Japan) was used for MS analysis. The ionization mode was set to ESI (negative).

(18) Copper nanocluster-mediated degradation of toxic organic dyes: a sustainable approach to water remediationRSC AdvDecember 22, 2025Aarya, Kavya P., Chanchal N. S., Devika V., Athira Sathyan, Supratik Sen Mojumdarcharacterized using a Liquid Chromatograph-Mass Spectrometer (LC-MS; Shimadzu Scientific Instruments, Model: LCMS 8045), a Proton Nuclear Magnetic Resonance (1H NMR) spectrometer (JEOL, Model: JNM-ECZ500R), and an Ion Chromatograph

(19) Galantamine-loaded PLGA nanoparticles reduce oxidative stress and inflammation in a rat model of spinal cord injuryScientific ReportsDecember 12, 2025Fernanda Stapenhorst Franca, Laura Elena Sperling, Marcelo Garrido dos Santos, Cristian Euzebio Teixeira, Tiago Franco de Oliveira, Patrick Turck, Adriane Bello Klein, Patricia Pranke-tandem mass spectrometry (UHPLC-MS/MS). The analyses were conducted on a Nexera UFLC system coupled to an LCMS-8045 triple quadrupole mass spectrometer (Shimadzu, Japan). Separation was achieved using a Shim-pack XR-ODS II

(20) Exploring the potential of liver microphysiological systems of varied configurations to model cholestatic chemical effectsArchives of ToxicologyDecember 8, 2025Katharina S. Nitsche, Courtney Sakolish, Paul L. Carmichael, Philip Hewitt, Piyush Bajaj, Stephen S. Ferguson, Sarah M. Lloyd, Sarah S. Wilson, Hans Bouwmeester, Ivan Rusynanalysis. Bile acid analysis (de Bruijn et al. 2022) was performed on a triple quadrupole LC–MS/MS system (model LCMS-8045; Shimadzu, Kawasaki City, Japan) for two primary unconjugated bile acids (Cholic acid and Chenodeoxycholic

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