QPix 420 Microbial Colony Picker from Molecular Devices

Product Specs
ItemQPix 420 Microbial Colony Picker
CompanyMolecular Devices
Price Get Pricing Get Quote for this Product
Catalog NumberQPix 420
QuantityEA
ApplicationsAntibiotic Zone of Inhibition, Biofuels, Blue-White Screening, DNA Sequencing, Drug Discovery & Development, Monoclonal Antibodies (mAbs), Phage display, Plasmid engineering in synthetic biology, Protein Evolution, Synthetic Biology
Dimensions(WxDxH) 1460 x 770 x 750 mm (QPix 420 System without table)
Capacity3000 colonies per hour in white light, 2000 colonies per hour in fluorescent light
Plate Formats(Destination) Various, 24, 48, 96 or 384-well, including deep well

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Molecular Devices

3860 N First Street

San Jose, California 95134

United States

Phone: 408-747-1700

Company Profile

Website: www.moleculardevices.com

(1) In vivo pathway optimization in yeast via loxpsym-mediated shuffling of upstream activating sequencesNucleic Acids ResearchSeptember 17, 2025Ciaran Ruehmkorff, Ali Tafazoli Yazdi, Lena Hochreinpreculture were randomly picked into a 96-deepwell plate containing 1 ml of CSM (50 g/l xylose) using the QPix 420 colony picker (Molecular Devices, San José, USA). The cultures were incubated for 5 days at 30°C and

(2) A multi-faceted discovery strategy identifies functional antibodies binding to cysteine-rich domain 1 of hDKK1 for cancer immunotherapy via Wnt non-canonical pathwayOncogeneMay 20, 2025Linya Wang, Sean M. Peterson, Marisa Yang, Ana G. Lujan Hernandez, Tom Z. Yuan, Zhen Han, Vishwas Prabhu, Kara Y. Chan, Cameron F. Hu, Mouna Villalta, et al.isolated on 2YT agar plates containing 100 µg/mL carbenicillin. Single colonies were selected using QPix 420 (Molecular Devices, Sunnyvale, CA, USA) in 384-well plates containing 2YT and M13KO7 helper phage (Antibody

(3) Combining biosensor and metabolic network optimization strategies for enhanced L-threonine production in Escherichia coliBiotechnol Biofuels BioprodMarch 26, 2025Zhenqiang Zhao, Rongshuai Zhu, Xuanping Shi, Fengyu Yang, Meijuan Xu, Minglong Shao, Rongzhen Zhang, Youxi Zhao, Jiajia You, Zhiming Raoat 37 °C. Then, 190 clones were inoculated into two 96-deep well plates with fermentation medium by Qpix 420 (Molecular Devices) for 12 h and then fluorescence was determined. From these, the top 10 mutants with

(4) Global Protein Interactome Mapping in Rice Using Barcode‐Indexed PCR Coupled with HiFi Long‐Read SequencingAdvanced ScienceJanuary 22, 2025Xixi Liu, Dandan Xia, Jinjin Luo, Mengyuan Li, Lijuan Chen, Yiting Chen, Jie Huang, Yanan Li, Huayu Xu, Yang Yuan, et al.Station (TCS) Single PPI yeast colonies were picked by a high‐throughput microbial colony picker system (QPix 420, Molecular Devices, San Jose, USA) or manually into the wells of a 96‐well plate containing freshly

(5) Screening of Lactic Acid Bacteria Isolated from Fermented Cowpea and Optimization of Biomass Production ConditionsFoodsJanuary 7, 2025Hong Xu, Danyang Li, Xue Jiang, Qi Pei, Zhengqin Li, Philippe Madjirebaye, Mingyong Xie, Tao Xiong, Zhanggen LiuAfter incubation at 37 °C for 48 h, a single colony (yellow color around the colonies) was selected by Qpix 420 (Molecular Devices, UK Limited, Wokingham, UK) for isolation and purification for further screening

(6) Automated characterization and analysis of expression compatibility between regulatory sequences and metabolic genes in Escherichia coliSynthetic and Systems BiotechnologyDecember 1, 2024Xiao Wen, Jiawei Lin, Chunhe Yang, Ying Li, Haijiao Cheng, Ye Liu, Yue Zhang, Hongwu Ma, Yufeng Mao, Xiaoping Liao, et al.the resuspended solution was plated onto SOC agar plates containing appropriate antibiotics using the QPix 420 clone picker (Molecular Devices, USA) and incubated at 37 °C until colonies appeared. The QPix 420 clone

(7) A VHH single-domain platform enabling discovery and development of monospecific antibodies and modular neutralizing bispecifics against SARS-CoV-2 variantsAntibody TherapeuticsMay 3, 2024Marisa L Yang, Tom Z Yuan, Kara Y Chan, Lin Ding, Zhen Han, Hector Franco, Carson Holliday, Shruthi Kannan, Edgar Davidson, Benjamin J Doranz, et al.were isolated on 2YT agar plates with 100 μg/ml carbenicillin, and single colonies were picked using QPix 420 (Molecular Devices) into 384-well plates containing 2YT with M13KO7 helper phage to express phage for

(8) Machine Learning-Guided Optimization of p-Coumaric Acid Production in YeastACS Synthetic BiologyApril 19, 2024Sara Moreno-Paz, Rianne van der Hoek, Elif Eliana, Priscilla Zwartjens, Silvia Gosiewska, Vitor A. P. Martins dos Santos, Joep Schmitz, Maria Suarez-Diezcolonies appeared on the plate after 3 days of incubation at 30 °C. Single colonies were picked with Qpix 420 (Molecular Devices) into 96-well plates containing YEPhD agar medium and a selection agent and regrown

(9) Combinatorial optimization of pathway, process and media for the production of p-coumaric acid by Saccharomyces cerevisiaeMicrob BiotechnolMarch 25, 2024Sara Moreno-Paz, Rianne van der Hoek, Elif Eliana, Vitor A. P. Martins Dos Santos, Joep Schmitz, Maria Suarez-DiezColonies appeared on the plate after 3 days of incubation at 30°C. Single colonies were picked with Qpix 420 (Molecular Devices) into a 96‐well plate containing YEPhD agar medium and selection agent and regrown

(10) The High-Throughput Screening of Microorganisms to Eliminate Ethyl Carbamate in Chinese LiquorFoodsMarch 13, 2024Zirui Yin, Jianghua Li, Jian Chen, Guocheng Du, Xinrui ZhaoMicroorganisms Primary screening: All individual colonies grown in the M9 agar medium were sub-cultured by Qpix420 (Molecular Devices, San Jose, CA, USA) into 96-deep-wells containing M9 medium with 5.0 g/L urea and

(11) Biocontrol of Escherichia coli O157:H7 by Enterobacter asburiae AEB30 on intact cantaloupe melonsMicrob BiotechnolMarch 11, 2024Thao D. Tran, Sang In Lee, Robert Hnasko, Jeffery A. McGarveyresulting colonies were transferred to 96‐well plates containing tryptic soy broth (TSB) (Oxoid) using a QPix420 automated picking robot (Molecular Devices, San Jose, CA, USA) (Figure 1). In total, 7768 isolates were

(12) Continuous synthesis of E. coli genome sections and Mb-scale human DNA assemblyNatureJuly 20, 2023Jérôme F. Zürcher, Askar A. Kleefeldt, Louise F. H. Funke, Jakob Birnbaum, Julius Fredens, Simona Grazioli, Kim C. Liu, Martin Spinck, Gianluca Petris, Pierre Murat, et al.subsection of the plate and linearly scaling to the whole surface or using automated counting on the QPIX420 system (Molecular Devices; settings: debris, ~0.2; axis ratio, ~0.25). For experiments in recA-deletion

(13) Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike proteinCell Host & MicrobeSeptember 14, 2022Kamyab Javanmardi et al.525 (Beckman Coulter) acoustic liquid handler, a Tecan Fluent robotic liquid handler (Tecan), and the QPix 420 Colony Picker (Molecular Devices) to assemble Golden Gate constructs. We arranged parts, either IDT

(14) Visualizing the pH in Escherichia coli Colonies via the Sensor Protein mCherryEA Allows High-Throughput Screening of Mutant LibrariesmSystemsJune 28, 2022Fabian Stefan Franz Hartmann, Tamara Weiß, Jing Shen, Dóra Smahajcsik, Simonas Savickas, Gerd Michael Seiboldmedium. Cells from single colonies on transformation plates were picked up using a colony-picking robot (QPix 420; Molecular Devices. LLC, USA) mounted with a bacterial 96-pin picking head and then transferred to the

(15) Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modalitybioRxivMay 18, 2022Jule Goike et al.on SD -Leu and 8–32 colonies per plate were picked into 2 mL microplates either by hand or using a QPIX 420 (Molecular Devices) automatic colony picker. Cultures were grown at 1000 rpm at 3 mm orbit at 30°C overnight.

(16) A cell-based phenotypic library selection and screening approach for the de novo discovery of novel functional chimeric antigen receptorsScientific reportsJanuary 21, 2022Fierle JK, Abram-Saliba J, Atsaves V, Brioschi M, de Tiani M, Reichenbach P, Irving M, Coukos G, Dunn SM.containing phagemid vectors expressing scFvs under control of a Lac promotor were picked by robot (Qpix420, Molecular Devices) into 96-well PP U-form microplates (Greiner, cat. 650,201) containing 200 µL of

(17) Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage librariesmAbsJanuary 1, 2022Yuan TZ, Garg P, Wang L, Willis JR, Kwan E, Hernandez AGL, Tuscano E, Sever EN, Keane E, Soto C, et al.were isolated on 2YT agar plates with 100 µg/ml carbenicillin and single colonies were picked using QPix 420 (Molecular Devices) into 384-well plates containing 2YT with M13KO7 helper phage (Antibody Design Labs)

(18) Rapid characterization of spike variants via mammalian cell surface displayMolecular CellDecember 16, 2021Kamyab Javanmardi et al.incubator for growth overnight (12–16 h). Colonies were screened the following day and picked using the QPix 420 (Molecular Devices), selecting only white colonies and avoiding green fluorescent colonies, which still

(19) Engineering the protein dynamics of an ancestral luciferaseNature CommunicationsDecember 1, 2021Andrea Schenkmayerova et al.the manual screening described above using a colony picking robot (Colony Picker, Molecular Devices QPix 420), a liquid handling robot (Bravo, Agilent) with a 96-tip head and the LARA robotic system (Greifswald,

(20) A Common Pathway for Activation of Host-Targeting and Bacteria-Targeting Toxins in Human Intestinal BacteriamBioSeptember 1, 2021Yiqiao Bao, Andrew A. Verdegaal, Brent W. Anderson, Natasha A. Barry, Jing He, Xiang Gao, Andrew L. Goodmanplates (termed BfN::TN plates) containing TYG medium with erythromycin using a microbial colony picker (QPix 420; Molecular Devices, San Jose, CA, USA). After 20 h anaerobic incubation at 37°C, an aliquot from each

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QPix 420 Bench-top Colony Picker

QPix 420 Microbial Colony Picker from Molecular Devices

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Molecular Devices

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QPix 420 Microbial Colony Picker from Molecular Devices

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