Y-27632 Dihydrochloride from Selleck Chemicals

Product Specs
ItemY-27632 Dihydrochloride
CompanySelleck Chemicals
Price $277.00Supplier Page View Company Product Page
Catalog NumberS1049
Quantity10mg
Purity99.86
TargetROCK
Storage3 years-20°C powder
FormulaC14H21N3O.2HCl

Specifications/Features

Ki, IC, EC, or working concentration: Ki: 0.14 µM for p160ROCK
IC50: 26 µM for PKC
IC50: 25 µM for cAMP-dependent protein kinase
IC50: >250 µM for myosin light-chain kinase

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Selleck Chemicals

14408 W Sylvanfield Drive

Houston, Texas TX 77014

United States

Phone: Toll Free: (877) 796-6397 (US and Canada only)
Tel: (832) 582-8158
Fax: (832) 582-8590

Email: sales@selleckchem.com

Company Profile

Website: www.selleckchem.com

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(2) Establishment, biobanking, and multi-omics characterization of 41 patient-derived colorectal cancer organoids: MYC/PRC classificationTranslational OncologySeptember 1, 2026You Jin Lee, Jae Hyun Park, Hee Ju Nam, Soon-Chan Kim, Min Jung Kim, Seung-Yong Jeong, Ji Won Park, Ja-Lok KuCat#17101–015), hyaluronidase (20 µg mL⁻¹, Sigma-Aldrich, Cat#H3506), and Y-27632 (10 µM, Selleckchem, Cat#S1049). The cell suspension was filtered through a 100 µm strainer (SPL Life Sciences, Cat#93100), centrifuged

(3) E- and N-cadherin drive hepatic polarity and lumen elongation via opposing effects on RhoA activityJ Cell BiolAugust 3, 2026Junya Hayase, Li Yang, Yu-Heng Zhou, Kangji Wang, Cheng-Ran Xu, Erfei Biliver explants were cultured for 2 days in the presence of DMSO (D2650; Sigma-Aldrich) or 1 µM Y27632 (S1049; Selleck). Antibodies and chemicals Anti-E-cadherin (36/E-cadherin, 610182) and anti-N-cadherin (32/N-cadherin,

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(12) A feeder-free culture system supports long-term expansion and germline competence of bovine formative embryonic stem cells†Biology of ReproductionJuly 15, 2026Lei Chen, Furui Wang, Jiale He, Mingwei Sun, Yiru Wang, Yinjuan Wang, Shumin Wang, Lei An, Guangyin Xi, Jianhui Tianresuspended in DPBS containing 30% Matrigel (Corning, 354230) and 10 μM ROCK inhibitor Y-27632 (Selleck, S1049). A total of 5 × 106 cells in 100 μL were injected subcutaneously into the Inguinal flank of 8-week-old

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(20) Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effectsCellJune 25, 2026Sriram Pendyala, Katie Partington, Nicholas Bradley, Abbye E. McEwen, Gwenneth Straub, Hyeon-Jin Kim, Shawn Fayer, Daniel Lee Holmes, Katherine A. Sitko, Riddhiman K. Garge, et al.until cells dissociated, then resuspended the cells in mTeSR Plus with 10 μM Y-27632 (SelleckChem, S1049) and replated. Media changes without re-plating used mTeSR Plus only. Cells were tested routinely for

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