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Protein Biochemistry
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PAC-1
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PAC-1
PAC-1
PAC-1 from Cayman Chemical
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Citations:
(2)
Figures:
(2)
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Supplier Page from
Cayman Chemical for
PAC-1
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Description
A procaspase-3 activator and a potential drug treatment in cancer cell lines with elevated levels of procaspase-3; exhibits an IC50 value of 3 nM for induction of cancer cell death without affecting non-cancerous cells
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
PAC-1
Company
Cayman Chemical
Price
$930.00
Supplier Page
View Company Product Page
Catalog Number
10009317
Quantity
250 mg
Research Area
Apoptosis, Cancer, Cell Biology, Cell Death, Cytosolic & Secreted Proteases, Proteolysis
Format
A crystalline solid
Molecular Weight
392.5
Purity
≥98%
Storage
-20
Formula
C23H28N4O2
Origin
USA
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (2)
(1)
ADS024, a single-strain live biotherapeutic product of Bacillus velezensis alleviates dextran sulfate-mediated colitis in mice, protects human colonic epithelial cells against apoptosis, and maintains epithelial barrier function
Frontiers in microbiology
January 1, 2023
Irwin S, Chupina Estrada A, Nelson B, Bullock A, Limketkai B, Ho W, Acton S, Chesnel L, Koon HW.
filtrate of ADS024 at 1X dilution with or without adding 10 μM procaspase activating compound 1/PAC1 (#
10009317
,
Cayman Chemical
). PAC1 is an activator of caspase 3 cleavage.
Promega
RealTime-Glo Annexin V apoptosis assay
(2)
ADS024, a Bacillus velezensis strain, protects human colonic epithelial cells against C. difficile toxin-mediated apoptosis
Frontiers in microbiology
January 1, 2022
Xie Y, Chupina Estrada A, Nelson B, Feng H, Pothoulakis C, Chesnel L, Koon HW.
and DSM7 at 0.0001X dilution with or without adding 10 μM procaspase activating compound 1 or PAC1 (#
10009317
,
Cayman Chemical
). PAC1 was used to activate caspase three cleavage. Reagents of
Promega
RealTime-Glo Annexin V apoptosis assay
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PAC-1 from Cayman Chemical
Supplier Page
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$930.00
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