Supplier Page from Cayman Chemical for PI-103
Ki, IC, EC, or working concentration: DNA-PK: IC50 = 2 nM p110a: IC50 = 8 nM mTORC1: IC50 = 20 nM PI3-KC2b: IC50 = 26 nM p110d: IC50 = 48 nM mTORC2: IC50 = 83 nM p110b: IC50 = 88 nM p110g: IC50 = 150 nM PI-103 exhibits antiproliferative activity against a panel of glioma cell lines in vitro at a concentration of 0.5 µM