AG 490 from Tocris Bioscience, a Bio-Techne Brand

Sizes Available: 10 mg (also 50 mg)

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

(2) PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapyEMBO molecular medicineFebruary 1, 2017Azad A, Yin Lim S, D'Costa Z, Jones K, Diana A, Sansom OJ, Kruger P, Liu S, McKenna WG, Dushek O, et al.

(3) Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer CellsInternational journal of molecular sciencesNovember 16, 2015Zhao LC, Li J, Liao K, Luo N, Shi QQ, Feng ZQ, Chen DL.

(4) YangZheng XiaoJi exerts anti-tumour growth effects by antagonising the effects of HGF and its receptor, cMET, in human lung cancer cellsJournal of translational medicineAugust 27, 2015Jiang WG, Ye L, Ruge F, Owen S, Martin T, Sun PH, Sanders AJ, Lane J, Satherley L, Weeks HP, et al.

(5) The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signalingMolecular cancerJuly 29, 2015Tactacan CM, Phua YW, Liu L, Zhang L, Humphrey ES, Cowley M, Pinese M, Biankin AV, Daly RJ.

(9) Adenosine augments IL-10-induced STAT3 signaling in M2c macrophagesJournal of leukocyte biologyDecember 1, 2013Koscsó B, Csóka B, Kókai E, Németh ZH, Pacher P, Virág L, Leibovich SJ, Haskó G.

(10) Inactivation of JAK2/STAT3 signaling axis and downregulation of M1 mAChR cause cognitive impairment in klotho mutant mice, a genetic model of agingNeuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyJuly 1, 2013Park SJ, Shin EJ, Min SS, An J, Li Z, Hee Chung Y, Hoon Jeong J, Bach JH, Nah SY, Kim WK, et al.

(11) High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell deathProceedings of the National Academy of Sciences of the United States of AmericaApril 3, 2012Fox JT, Sakamuru S, Huang R, Teneva N, Simmons SO, Xia M, Tice RR, Austin CP, Myung K.

(12) PLZF is a regulator of homeostatic and cytokine-induced myeloid developmentGenes & developmentSeptember 1, 2009Doulatov S, Notta F, Rice KL, Howell L, Zelent A, Licht JD, Dick JE.

(13) IL-9/IL-9 receptor signaling selectively protects cortical neurons against developmental apoptosisCell death and differentiationOctober 1, 2008Fontaine RH, Cases O, Lelièvre V, Mesplès B, Renauld JC, Loron G, Degos V, Dournaud P, Baud O, Gressens P.

(15) JAK/STAT and PI3K/AKT pathways form a mutual transactivation loop and afford resistance to oxidative stress-induced apoptosis in cardiomyocytesCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2008Lu Y, Zhou J, Xu C, Lin H, Xiao J, Wang Z, Yang B.

AG 490