17-AAG from Tocris Bioscience, a Bio-Techne Brand

Product Specs
Item17-AAG
CompanyTocris Bioscience, a Bio-Techne Brand
Price $232.00Supplier Page View Company Product Page
Catalog Number1515/1
Quantity1 mg
Purity98%
Molecular Weight585.7
Molecule Name17-Demethoxy-17-(2-propenylamino)geldanamycin
FormulaC31H43N3O8
StorageStore at -20°C

Specifications/Features

Sizes Available: 1 mg

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Identification of novel small molecule chaperone activators for neurodegenerative disease treatmentBiomedicine & PharmacotherapyJune 1, 2025Anita K Ho, Fiona Jeganathan, Magda Bictash, Han-Jou ChenScientific) for immunofluorescence staining. Compound and reagents used in this study included: 17-AAG (1515/1, Bio-Techne and A8476, Sigma), Arsenite (106277, Sigma), BAI1 (S8865, Selleck Chemicals LLC), DMSO (D2438,

(2) Fast and stable vapochromic response induced through nanocrystal formation of a luminescent platinum(II) complex on periodic mesoporous organosilicaScientific ReportsDecember 1, 2019Hiroki Matsukawa, Masaki Yoshida, Takahiro Tsunenari, Shunsuke Nozawa, Ayana Sato-Tomita, Yoshifumi Maegawa, Shinji Inagaki, Atsushi Kobayashi, Masako KatoR&D Laboratories, Inc., Nagakute, Aichi, 480-1192, Japan. *email: mkato@sci.hokudai.ac.jp Scientific Reports | (2019) 9:15151 | https://doi.org/10.1038/s41598-019-51615-w 1 www.nature.com/scientificreports/ www.nature.com/scientificreports Figure

(3) Heat Shock Protein 90 as a Prognostic Marker and Therapeutic Target for Adrenocortical CarcinomaFrontiers in endocrinologyJanuary 1, 2019Siebert C, Ciato D, Murakami M, Frei-Stuber L, Perez-Rivas LG, Monteserin-Garcia JL, Nölting S, Maurer J, Feuchtinger A, Walch AK, et al.

(4) Heat-shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK mitogen-activated protein kinase (MAPK) mechanism in mouse brainThe Journal of biological chemistryJune 23, 2017Lei W, Mullen N, McCarthy S, Brann C, Richard P, Cormier J, Edwards K, Bilsky EJ, Streicher JM.

(5) Hsp90 regulation of fibroblast activation in pulmonary fibrosisJCI insightFebruary 23, 2017Sontake V, Wang Y, Kasam RK, Sinner D, Reddy GB, Naren AP, McCormack FX, White ES, Jegga AG, Madala SK.

(6) Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductaseJournal of proteomicsJanuary 1, 2015Truman AW, Kristjansdottir K, Wolfgeher D, Ricco N, Mayampurath A, Volchenboum SL, Clotet J, Kron SJ.

(7) HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase βNature communicationsNovember 26, 2014Fang Q, Inanc B, Schamus S, Wang XH, Wei L, Brown AR, Svilar D, Sugrue KF, Goellner EM, Zeng X, et al.

(8) The hsp70 inhibitor VER155008 induces paraptosis requiring de novo protein synthesis in anaplastic thyroid carcinoma cellsBiochemical and biophysical research communicationsNovember 7, 2014Kim SH, Kang JG, Kim CS, Ihm SH, Choi MG, Yoo HJ, Lee SJ.

(9) HSF1 deficiency and impaired HSP90-dependent protein folding are hallmarks of aneuploid human cellsThe EMBO journalOctober 16, 2014Donnelly N, Passerini V, Dürrbaum M, Stingele S, Storchová Z.

(10) Pertuzumab Increases 17-AAG-Induced Degradation of ErbB2, and This Effect Is Further Increased by Combining Pertuzumab with TrastuzumabPharmaceuticals (Basel, Switzerland)June 28, 2012Hughes JB, Rødland MS, Hasmann M, Madshus IH, Stang E.

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17-AAG

17-AAG from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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17-AAG from Tocris Bioscience, a Bio-Techne Brand

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