(R)-CR8 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
Item(R)-CR8
CompanyTocris Bioscience, a Bio-Techne Brand
Price $335.00Supplier Page View Company Product Page
Catalog Number3605/10
Purity98%
Molecular Weight540.92
Molecule Name(2R)-2-[[9-(Methylethyl)-6-[[[4-(2-pyridinyl)phenyl]methyl]amino]-9H-purin-2-yl]amino]-1-butanol trihydrochloride
FormulaC24H29N7O.3HCl
StorageStore at +4°C
Quantity10 mg

Sizes Available: 10 mg

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United States

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(1) The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin KNatureSeptember 1, 2020Słabicki M, Kozicka Z, Petzold G, Li YD, Manojkumar M, Bunker RD, Donovan KA, Sievers QL, Koeppel J, Suchyta D, et al.

(2) F-box protein FBXO31 directs degradation of MDM2 to facilitate p53-mediated growth arrest following genotoxic stressProceedings of the National Academy of Sciences of the United States of AmericaJuly 14, 2015Malonia SK, Dutta P, Santra MK, Green MR.

(3) Spinal cord injury causes brain inflammation associated with cognitive and affective changes: role of cell cycle pathwaysThe Journal of neuroscience : the official journal of the Society for NeuroscienceAugust 13, 2014Wu J, Zhao Z, Sabirzhanov B, Stoica BA, Kumar A, Luo T, Skovira J, Faden AI.

(5) TrkB.T1 contributes to neuropathic pain after spinal cord injury through regulation of cell cycle pathwaysThe Journal of neuroscience : the official journal of the Society for NeuroscienceJuly 24, 2013Wu J, Renn CL, Faden AI, Dorsey SG.

(R)-CR8