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PKC 412
PKC 412 from Cayman Chemical
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Citations:
(2)
Supplier Page
Supplier Page from
Cayman Chemical for
PKC 412
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Description
A cell-permeable, reversible inhibitor of several kinases, including PKCα, PKCβ, PKCγ, Syk, FLK1, Akt,PKA, c-Kit, C-Fgr, c-Src, FLT3, PDFRβ, VEGFR1, and VEGF2, with IC50 values ranging from 80-500 nM
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
PKC 412
Company
Cayman Chemical
Price
$31.00
Supplier Page
View Company Product Page
Catalog Number
10459
Quantity
1 mg
Research Area
Apoptosis, cAMP Signaling, Cancer, Cell Biology, Cell Death, Cell Signaling, Growth Factor Receptor Signaling, Growth Factor Receptors, PI3K/Akt/mTOR Signaling, PKC Signaling
Format
A crystalline solid
Molecular Weight
570.6
Purity
≥98%
Storage
-20
Formula
C35H30N4O4
Origin
CHN
Type
Inhibitors
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (2)
(1)
A kinome inhibitor screen implicates adhesion and growth factor signaling in cellular recovery after caspase activation
bioRxiv
January 8, 2026
Maddalena Nano, Jacob Harwood, Gabriel Lukaszewicz, Alexander Kagan, Leonid Peshkin, Denise J. Montell
Scientific,), Lestautinib (CAS: 111358–88-4, cat#
12094
,
Cayman chemicals
),
PKC 412
(CAS: 120685–11-2, cat#
10459
,
Cayman chemicals
), RK 2446 (CAS: 213743–31-8, cat#
15135
,
Cayman chemicals
), Vargatef (CAS: 928326–83-4,
(2)
Targeting FLT3-TAZ signaling to suppress drug resistance in blast phase chronic myeloid leukemia
Molecular Cancer
November 6, 2023
Ji Eun Shin, Soo-Hyun Kim, Mingyu Kong, Hwa-Ryeon Kim, Sungmin Yoon, Kyung-Mi Kee, Jung Ah Kim, Dong Hyeon Kim, So Yeon Park, Jae Hyung Park,
et al.
(
Selleckchem
,
S1033
), Ponatinib (
Selleckchem
,
S1490
), Quizartinib (
Selleckchem
,
S1526
), Midostaurin (
Cayman
,
10459
),
AZD-1480
(
Selleckchem
,
S2162
), C188-9 (Selleckchem, S8605), BP-1-102 (Selleckchem, S7769), Ruxolitinib
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PKC 412 from Cayman Chemical
Supplier Page
View Company Product Page
$31.00
Product Specs
Company Info
Citations
Reviews
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