DAPT from Santa Cruz Biotechnology, Inc.

Storage:
208255-80-5

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

(1) Apicosome: Newly identified cell-type-specific organelle in mouse cochlear and vestibular hair cellsiScienceApril 21, 2023Li X, Zhao Q, Yu X, Cao W, Zhang Y, Feng W, Jiang L, He DZ, Qi RZ, Huang P.

(3) Subcellular dynamics and functional activity of the cleaved intracellular domain of the Na(+) channel β1 subunitThe Journal of biological chemistryAugust 1, 2022Haworth AS, Hodges SL, Capatina AL, Isom LL, Baumann CG, Brackenbury WJ.

(4) Cigarette smoke upregulates Notch-1 signaling pathway and promotes lung adenocarcinoma progressionToxicology lettersFebruary 1, 2022Chiappara G, Di Vincenzo S, Sangiorgi C, Di Sano C, D'Anna C, Zito G, Cipollina C, Vitulo P, Bertani A, Pace E.

(5) S1P induces proliferation of pulmonary artery smooth muscle cells by promoting YAP-induced Notch3 expression and activationThe Journal of biological chemistryJanuary 1, 2021Wang J, Yan X, Feng W, Wang Q, Shi W, Chai L, Zhang Q, Chen Y, Liu J, Qu Z, et al.

(6) Reciprocal communication between astrocytes and endothelial cells is required for astrocytic glutamate transporter 1 (GLT-1) expressionNeurochemistry internationalOctober 1, 2020Martinez-Lozada Z, Robinson MB.experiments/wells, 10 μM N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester (DAPT, Santa Cruz SC201315) was included in the media and with every media exchange. In a subset of experiments, bEND.3 were allowed

(7) Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoidsNature cell biologyJanuary 1, 2020Motazedian A, Bruveris FF, Kumar SV, Schiesser JV, Chen T, Ng ES, Chidgey AP, Wells CA, Elefanty AG, Stanley EG.

(10) Notch-1 decreased expression contributes to leptin receptor downregulation in nasal epithelium from allergic turbinatesBiochimica et biophysica acta. Molecular basis of diseaseJune 1, 2019Bruno A, Di Sano C, Lorusso F, Dino P, Russo D, Ballacchino A, Gallina S, Modica DM, Chiappara G, Simon HU, et al.

(11) SphK1/S1P mediates TGF-β1-induced proliferation of pulmonary artery smooth muscle cells and its potential mechanismsPulmonary circulationJanuary 1, 2019Wang J, Feng W, Li F, Shi W, Zhai C, Li S, Zhu Y, Yan X, Wang Q, Liu L, et al.

(12) DAPT, a γ-Secretase Inhibitor, Suppresses Tumorigenesis, and Progression of Growth Hormone-Producing Adenomas by Targeting Notch SignalingFrontiers in oncologyJanuary 1, 2019Feng J, Wang J, Liu Q, Li J, Zhang Q, Zhuang Z, Yao X, Liu C, Li Y, Cao L, et al.(10 ng/ml), nerve growth factor (10 ng/ml), and L-glutamine (0.5 mM). γ-secretase inhibitor, DAPT (sc201315), was purchased from Santa Cruz Biotechnology (Dallas, TX, USA). Microarray Hybridization Total RNA

(14) Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathwayInternational journal of molecular medicineMarch 1, 2018Liu Z, Li L, Chen W, Wang Q, Xiao W, Ma Y, Sheng B, Li X, Sun L, Yu M, et al.

(15) Quantitative proteomics analysis of the role of tetraspanin-8 in the drug resistance of gastric cancerInternational journal of oncologyFebruary 1, 2018Li L, Yang D, Cui D, Li Y, Nie Z, Wang J, Liang L.

(16) Polydatin Protects Diabetic Heart against Ischemia-Reperfusion Injury via Notch1/Hes1-Mediated Activation of Pten/Akt SignalingOxidative medicine and cellular longevityJanuary 1, 2018Yu L, Li Z, Dong X, Xue X, Liu Y, Xu S, Zhang J, Han J, Yang Y, Wang H.

(18) Molecular Profiling of Circulating Tumour Cells Identifies Notch1 as a Principal Regulator in Advanced Non-Small Cell Lung CancerScientific reportsNovember 30, 2016Mariscal J, Alonso-Nocelo M, Muinelo-Romay L, Barbazan J, Vieito M, Abalo A, Gomez-Tato A, Maria de Los Angeles CC, Garcia-Caballero T, Rodriguez C, et al.

(19) Paradoxical E-cadherin increase in 5FU-resistant colon cancer is unaffected during mesenchymal-epithelial reversion induced by γ-secretase inhibitionLife sciencesJanuary 15, 2016Dinicola S, Pasqualato A, Proietti S, Masiello MG, Palombo A, Coluccia P, Canipari R, Catizone A, Ricci G, Harrath AH, et al.

(20) Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restrictionNature immunologyJanuary 1, 2016Zhao E, Maj T, Kryczek I, Li W, Wu K, Zhao L, Wei S, Crespo J, Wan S, Vatan L, et al.

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