4mu8C from Tocris Bioscience, a Bio-Techne Brand

Product Specs
Item4mu8C
CompanyTocris Bioscience, a Bio-Techne Brand
Price $264.00Supplier Page View Company Product Page
Catalog Number4479/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight204.18
Molecule Name7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde
FormulaC11H8O4
StorageStore at -20°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal SurvivalInternational journal of molecular sciencesAugust 22, 2022Eesmaa A, Yu LY, Göös H, Danilova T, Nõges K, Pakarinen E, Varjosalo M, Lindahl M, Lindholm P, Saarma M.

(2) Saponin-based adjuvant-induced dendritic cell cross-presentation is dependent on PERK activationCellular and molecular life sciences : CMLSApril 9, 2022Huis In 't Veld LGM, Ho NI, Wassink M, den Brok MH, Adema GJ.

(3) The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactorThe Journal of biological chemistryJanuary 1, 2021Eesmaa A, Yu LY, Göös H, Nõges K, Kovaleva V, Hellman M, Zimmermann R, Jung M, Permi P, Varjosalo M, et al.

(4) Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPReLifeDecember 24, 2019Amin-Wetzel N, Neidhardt L, Yan Y, Mayer MP, Ron D.

(5) Evaluation of Compound Activity in Primary Human Intestinal Organoids Using Gene Expression and HistologyCurrent protocols in pharmacologyJune 1, 2019Marchelletta R, Yu J, Moon C, Kim MM.

(6) Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPRCellMay 16, 2019Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, et al.

(7) Modulation of the sigma-1 receptor-IRE1 pathway is beneficial in preclinical models of inflammation and sepsisScience translational medicineFebruary 6, 2019Rosen DA, Seki SM, Fernández-Castañeda A, Beiter RM, Eccles JD, Woodfolk JA, Gaultier A.

(8) Monounsaturated fatty acids protect against palmitate-induced lipoapoptosis in human umbilical vein endothelial cellsPloS oneJanuary 1, 2019Lee DM, Sevits KJ, Battson ML, Wei Y, Cox-York KA, Gentile CL.

(9) Mitochondrial Activity and Unfolded Protein Response are Required for Neutrophil DifferentiationCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Tanimura A, Miyoshi K, Horiguchi T, Hagita H, Fujisawa K, Noma T.(G7345; LKT laboratories, St. Paul, MN) as PERK inhibitor, and 8-formyl-4-methylumbelliferone (4μ8C) (4479/10; R&D Systems, Minneapolis, MN) as IRE1α-XBP1 inhibitor. To inhibit mitochondrial ATP production, we

(10) A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein ResponseCellDecember 14, 2017Amin-Wetzel N, Saunders RA, Kamphuis MJ, Rato C, Preissler S, Harding HP, Ron D.

(11) TLR7-mediated activation of XBP1 correlates with the IFNα production in humansCytokineJune 1, 2017Beisel C, Ziegler S, Martrus Zapater G, Chapel A, Griesbeck M, Hildebrandt H, Lohse AW, Altfeld M.

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4mu8C

4mu8C from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

Citations (11)

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4mu8C from Tocris Bioscience, a Bio-Techne Brand

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