Purmorphamine, Smoothened receptor agonist from Abcam

Product Specs
ItemPurmorphamine, Smoothened receptor agonist
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab120933
Molecule NamePurmorphamine, Smoothened receptor agonist
TypeActivator/Agonist
Quantity5 mg, 25 mg

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Metabolomics of Multiple System Atrophy Patient-Derived Striatal Medium Spiny NeuronsBiomoleculesJanuary 26, 2026Nadine J. Smandzich, Heike Bähre, Thomas Gschwendtberger, Stephan Greten, Lan Ye, Martin Klietz, Alessio Di Fonzo, Lisa M. Henkel, Florian Wegner1 µM D, 10 µM SB and 1 µM IWP-2 were added on day 2; additionally, 1 µM purmorphamine (PMA, Abcam, ab120933) was added on day 4. On days 6 and 8, 1 µM IWP-2 and 1 µM PMA were supplemented. On day 10, the N2 medium

(2) Proteomics of Patient-Derived Striatal Medium Spiny Neurons in Multiple System AtrophyCellsSeptember 6, 2025Nadine J. Smandzich, Andreas Pich, Thomas Gschwendtberger, Stephan Greten, Lan Ye, Martin Klietz, Alessio Di Fonzo, Lisa M. Henkel, Florian Wegner1 µM IWP-2 were added to the N2 medium. The same concentrations and 1 µM purmorphamine (PMA, Abcam, ab120933) were supplemented on day 4. On day 6 and 8, the same two molecules and concentrations were added (1

(3) Ubiquitylation of BBSome is required for ciliary assembly and signalingEMBO reportsApril 5, 2023Chiuso F, Delle Donne R, Giamundo G, Rinaldi L, Borzacchiello D, Moraca F, Intartaglia D, Iannucci R, Senatore E, Lignitto L, et al.The following chemicals were used: Forskolin (40 μM; #F3917, Sigma‐Aldrich); Purmorphamine (10 μM; # ab120933 Abcam); somatostatin‐14 (10 μM; #38916–34‐6 Sigma‐Aldrich). Immunoprecipitation, pulldown assays, and immunoblot

(4) Dopaminergic co-transmission with sonic hedgehog inhibits abnormal involuntary movements in models of Parkinson's disease and L-Dopa induced dyskinesiaCommunications biologySeptember 22, 2021Malave L, Zuelke DR, Uribe-Cano S, Starikov L, Rebholz H, Friedman E, Qin C, Li Q, Bezard E, Kottmann AH.SIH184) was dissolved in 0.9% sterile saline and given at the same time as L-Dopa. pPurmorphamine (ABCam AB120933) was dissolved in a cocktail of Polyethylene glycol and ethanol in PBS and given 15 min before L-Dopa

(5) The TBC1D31/praja2 complex controls primary ciliogenesis through PKA-directed OFD1 ubiquitylationThe EMBO journalMay 17, 2021Senatore E, Chiuso F, Rinaldi L, Intartaglia D, Delle Donne R, Pedone E, Catalanotti B, Pirone L, Fiorillo B, Moraca F, et al.cycloheximide (100 μM; #C104450, Sigma‐Aldrich), MG132 (10 μM; #C2211, Sigma‐Aldrich); Purmorphamine (1 μM; # ab120933 Abcam); bafilomycin (1 μM; #B1793, Sigma‐Aldrich). Immunoprecipitation, pull‐down assays and immunoblot Cells

(6) Structural insight into small molecule action on FrizzledsNature communicationsJanuary 21, 2020Kozielewicz P, Turku A, Bowin CF, Petersen J, Valnohova J, Cañizal MCA, Ono Y, Inoue A, Hoffmann C, Schulte G.purmorphamine (9-cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine; Abcam #ab120933), and acetylcholine (ACh; Sigma #A6625) were used. SAG1.3 was dissolved in water at 10 mM or DMSO at

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Purmorphamine, Smoothened receptor agonist from Abcam

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Purmorphamine, Smoothened receptor agonist from Abcam

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