RECQL5-IN-1 from Aladdin Scientific

RECQL5-IN-1 (Compound 4a) acts as an orally effective RECQL5 inhibitor (targeting both enzymatic and nonenzymatic domain). RECQL5-IN-1 is a potent inhibitor of RECQL5 helicase activity ( IC 50 =46.3 nM). RECQL5-IN-1 inhibits RECQL5-WT cells and RECQL5-KO2 cells with IC 50 s of 4.8 µM and 19.6 µM, respectively. RECQL5-IN-1 can be used for the research of breast cancer.Form:Solid