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Protein Biochemistry
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DPCPX
DPCPX from MedChemExpress
Be the first to write a review!
Citations:
(11)
Supplier Page
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MedChemExpress for
DPCPX
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Description
DPCPX (PD 116948), a xanthine derivative, is a highly potent and selective
Adenosine A1 receptor
antagonist, with a
K
i
of 0.46 nM in
3
H-CHA binding to A1 receptors in rat whole brain membranes
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
DPCPX
Company
MedChemExpress
Price
$84.00
Supplier Page
View Company Product Page
Catalog Number
HY-100937
Quantity
10 mM * 1 mL
Type
Chemical
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.96%
Research Area
Cardiovascular Disease
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (11)
(1)
Cordycepin Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Inhibiting IL-6/IL-6R-Mediated p38 MAPK and NF-κB Activation Through Adenosine A2A Receptor Stimulation
Drug Des Devel Ther
March 24, 2026
Yu Liao, Weipeng Wei, Fuli Qin, Yusheng Ruan, Ting He, Jiansong He, Mingchao Wang, Taotao Liu, Jiemei Chen
obtained from Shanghai Aladdin Biochemical Technology Co., Ltd. (China); SCH58261 (
HY-19533
) and
DPCPX
(
HY-100937
) were supplied by
MedChemExpress
(MCE, Monmouth Junction, NJ, USA); BisBenzimide H 33342 (Hoechst 33342,
(2)
Cordycepin Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Inhibiting IL-6/IL-6R-Mediated p38 MAPK and NF-κB Activation Through Adenosine A2A Receptor Stimulation
Drug Des Devel Ther
March 24, 2026
Yu Liao, Weipeng Wei, Fuli Qin, Yusheng Ruan, Ting He, Jiansong He, Mingchao Wang, Taotao Liu, Jiemei Chen
obtained from Shanghai Aladdin Biochemical Technology Co., Ltd. (China); SCH58261 (
HY-19533
) and
DPCPX
(
HY-100937
) were supplied by
MedChemExpress
(MCE, Monmouth Junction, NJ, USA); BisBenzimide H 33342 (Hoechst 33342,
(3)
Cordycepin improves hyperactivation and acrosome reaction through adenosine receptors during human sperm capacitation in vitro
Reproductive Biology and Endocrinology
November 12, 2024
Lijun Shan, Linmei Gao, Yuhao Chai, Kun Li, Jianmin Yu, Fei Liang, Jiangfeng Qin, Ya Ni, Peibei Sun
kit was provided by BRED Life Science Technology (Shenzhen, China). The
inhibitors
to the A1 (
DPCPX
;
HY-100937
), A2b (MRS1754;
HY-14121
), and A3 (MRS1191;
HY-124543
) AdoRs were purchased from
MedChemExpress
(Shanghai,
(4)
Adenosine mediates the amelioration of social novelty deficits during rhythmic light treatment of 16p11.2 deletion female mice
Molecular Psychiatry
November 1, 2024
Jun Ju, Xuanyi Li, Yifan Pan, Jun Du, Xinyi Yang, Siqi Men, Bo Liu, Zhenyu Zhang, Haolin Zhong, Jinyuan Mai,
et al.
(A2A receptor antagonist,
HY-19533
,
MedChemExpress
) and 0.4 mg/mL
DPCPX
[31] (A1 receptor antagonist,
HY-100937
,
MedChemExpress
) were dissolved in a solution including 5% DMSO and 95%
corn
oil. The intragastric administrations
(5)
Astrocytes in preoptic area regulate acute nociception-induced hypothermia through adenosine receptors
CNS neuroscience & therapeutics
May 1, 2024
Jia J, Chen T, Chen C, Si T, Gao C, Fang Y, Sun J, Wang J, Zhang Z.
the spot.
Clozapine‐N‐oxide (CNO
) (
Tocris
, 4936), fluorocitric acid (FC) (Sigma, F9634), DCPCX (
MCE
,
HY‐100937
),
SCH58261
(
Selleck
,
S8104
), and CGS 21680 (
Selleck
,
S2153
) were prepared as stock solutions in
dimethyl sulfoxide (DMSO
(6)
Beyond the Nucleus: Plastic Chemicals Activate G Protein-Coupled Receptors
Environ Sci Technol
March 19, 2024
Molly McPartland, Sarah Stevens, Zdenka Bartosova, Ingrid Gisnås Vardeberg, Johannes Völker, Martin Wagner
samples and to the ADORA1 antagonist 8-cyclopentyl-1,3-dipropylxanthine (DCPCX, 99.02%,
MedChemExpress
,
HY-100937
)31 or the MTNR1A antagonist
luzindole (97
%,
ThermoFisher
, J61915-#0).32 We used the EC80 of NECA (0.05
(7)
The metabolic role of the CD73/adenosine signaling pathway in HTR-8/SVneo cells: A Double-Edged Sword?
Heliyon
February 15, 2024
Guangmin Song, Dan Zhang, Jianan Zhu, Andi Wang, Xiaobo Zhou, Ting-Li Han, Hua Zhang
5′-N-ethylcarboxamidoadenosine (NECA;
HY-103173
;
MCE
, China, 30 nM), 8-cyclopentyl-1,3-dipropylxanthine (
DPCPX
,
HY-100937
;
MCE
, China, 100 nM), ZM 241385 (
HY-19532
;
MCE
, China, 10 nM), and
MRS 1706
(
HY-103186
;
MCE
, China,
(8)
Transcriptional control of pancreatic cancer immunosuppression by metabolic enzyme CD73 in a tumor-autonomous and -autocrine manner
Nature communications
June 8, 2023
Tang T, Huang X, Lu M, Zhang G, Han X, Liang T.
agents were used: MG132 (
S2619
,
Selleck
), chloroquine (S6999, Selleck), KW6002 (
S2790
,
Selleck
),
DPCPX
(
HY-100937
,
MedChemExpress
), CVT-6883 (
HY-10081
,
MedChemExpress
), reversine (
S7588
,
Selleck
), MK-2206 (
S1078
,
Selleck
),
(9)
PD 116,948, a highly selective A1 adenosine receptor antagonist
Life sciences
February 9, 1987
Haleen SJ, Steffen RP, Hamilton HW.
(10)
Binding of the A1-selective adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes
Naunyn-Schmiedeberg's archives of pharmacology
January 1, 1987
Bruns RF, Fergus JH, Badger EW, Bristol JA, Santay LA, Hartman JD, Hays SJ, Huang CC.
(11)
Proceedings: The 24-hour control of intragastric pH by cimetidine, a new H2-receptor antagonist, in normal subjects and in patients with duodenal ulcer
Gut
October 1, 1975
Pounder RE, Williams JG, Misiewicz JJ, Milton-Thompson GJ.
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DPCPX from MedChemExpress
Supplier Page
View Company Product Page
$84.00
Product Specs
Company Info
Citations
Reviews
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