Description
A triterpenoid with diverse biological activities; reduces LPS-induced NO production and increases HO-1 levels in RAW 264.7 cells at 50 µM; an FXR agonist that induces reporter gene expression in HEK293 cells expressing recombinant human FXR (EC50 = 5 µM); inhibits complement-dependent hemolysis of isolated sheep red blood cells (IC50 = 48 µM); reduces HIV-1 viral proliferation in MT-4 cells (IC50 = 7.8 µg/ml)