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Protein Biochemistry
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AM966
AM966 from MedChemExpress
Be the first to write a review!
Citations:
(3)
Supplier Page
Supplier Page from
MedChemExpress for
AM966
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Description
AM966 is a high affinity, selective, oral
LPA
1
-antagonist, inhibits LPA-stimulated intracellular calcium release (
IC
50
=17 nM)
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
AM966
Company
MedChemExpress
Price
$76.00
Supplier Page
View Company Product Page
Catalog Number
HY-15277
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.86%
Type
Chemical
Molecular Weight
490.93
Formula
C₂₇H₂₃ClN₂O₅
Research Area
Inflammation/Immunology
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (3)
(1)
EBV promotes alveolar trabecula resorption via extracellular vesicle remodeling by group IIA secreted phospholipase A2
Journal of Lipid Research
April 1, 2026
Akane Kanamori, Akira Hasuike, Kai Kudo, Joaquim Carreras, Takanobu Shimizu, Shunya Nakayama, Ryo Yanagiya, Ryo Koike, Yorimasa Ogata, Osamu Takeichi,
et al.
containing 5% CO2 for 24 or 48 h. For
inhibitor
treatment, cells were pretreated with 10 μM
AM966
(
HY-15277
,
MedChemExpress
) or 1 μM
EP4 receptor antagonist 1
(
HY-133123
,
MedChemExpress
) 30 min prior to EV exposure. Treatment
(2)
Antidepressants activate the lysophosphatidic acid receptor LPA(1) to induce insulin-like growth factor-I receptor transactivation, stimulation of ERK1/2 signaling and cell proliferation in CHO-K1 fibroblasts
Biochemical pharmacology
June 15, 2015
Olianas MC, Dedoni S, Onali P.
(3)
A novel, orally active LPA(1) receptor antagonist inhibits lung fibrosis in the mouse bleomycin model
British journal of pharmacology
August 1, 2010
Swaney JS, Chapman C, Correa LD, Stebbins KJ, Bundey RA, Prodanovich PC, Fagan P, Baccei CS, Santini AM, Hutchinson JH,
et al
.
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AM966 from MedChemExpress
Supplier Page
View Company Product Page
$76.00
Product Specs
Company Info
Citations
Reviews
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