Estradiol from MedChemExpress

Product Specs
ItemEstradiol
CompanyMedChemExpress
Price $61.00Supplier Page View Company Product Page
Catalog NumberHY-B0141
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.93%
TypeChemical
Molecular Weight272.38
FormulaC₁₈H₂₄O₂
Research AreaEndocrinology; Cancer

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(1) DMRT2 participates in chicken gonadal development by regulating CHUK and SOX9-mediated cell proliferation and apoptosisPoultry ScienceSeptember 1, 2026Xiao Lin, Zidi Jin, Aneeqa Imtiaz, Jing Ge, Haizhou Gong, Yihui Zhang, Yun Zheng, Minmeng Zhao, Daoqing Gong, Long Liu, et al.treatment of chicken embryos To establish a male-to-female sex reversal model, 17β-estradiol (Cat. No. HY-B0141; MedChemexpress Biotechnology, Inc., New Jersey, USA) was injected into the blunt end of E2.5-stage

(2) Sex-dependent protective responses of taurine in ameliorating radiation-induced intestinal injury: gut microbiota reprogramming in males and estrogen-dependent immunity in femalesInt J Biol SciAugust 24, 2026Xudong Ding, Jia Du, Zhaoyu Wang, Lu Lu, Saijun Fan17β-estradiol (17β-E2) supplementation Female C57BL/6J mice were randomly assigned to OVX or OVX with 17β-E2 (HY-B0141, MedChemExpress) supplementation (OVX+17β-E2). After one week of acclimatization, both groups underwent

(3) Gut commensal Olsenella profusa promotes endometriosis via lysophosphatidylcholine metaboliteCell Rep MedAugust 18, 2026Yuying Chen, Ziwei Zhou, Biqi Huang, Xunjie Xie, Yuzhen Cao, Shanshui Zeng, Bingyu Li, Fangbo Xia, Li Peng, Jiarui Liang, et al.2-dipalmitoyl-sn-glycero-3-phosphocholine (PC)",Macklin,Cat# D863688; CAS# 63-89-8 β-Estradiol,MedChemExpress (MCE),Cat# HY-B0141; CAS# 50-28-2 TRIzol,Invitrogen,Cat# 15596026 ExtractRNA reagent,Vazyme,Cat# R401-01 DMEM/F-12 culture

(4) A Regulatory Element in the Intrinsically Disordered C-Terminal Region of LMTK3 Modulates Its Kinase Domain Interactions and Breast Cancer PhenotypesCellsAugust 17, 2026Andrea Lauer Betrán, Alessandro Agnarelli, Mark Samuels, Viviana Vella, Reza Shirazi Nia, Daniel De Vega, Niloufar Poudine, Daniela Carter-Lopez, Angeliki Ditsiou, Murat Eravci, et al.subcutaneous injections of 17β-oestradiol (20 µg in 20 µL; MedChemExpress, Monmouth Junction, NJ, USA, cat. no. HY-B0141) prepared in a 9:1 corn oil:ethanol vehicle, beginning three days before tumour cell inoculation and

(5) KAT6B/A::KANSL1 uterine sarcoma - A case with recurrences following uterine morcellation and the development of primary cell line modelGynecol Oncol RepJuly 13, 2026Lauren Chen, Jiahui Liu, Isabelle Nechala, Pooja Praveen Kumar, Carol Ewanowich, Melissa Levecchia, Christa Aubrey, Yangxin Fu, Cheng-Han Leewell) showing the effects on cell viability with increasing concentration of estradiol (MedChemExpress, HY-B0141, New Jersey, USA) compared to vehicle control (0.1% DMSO). Error bars reflect standard error of mean

(6) RHINO: An Integrative Multi-Omics Framework Linking Circadian Physiology to Precision MedicineAdv Sci (Weinh)July 7, 2026Ying Chen, Chengxuan Chen, Dishu Zhou, Panpan Liu, Roberto E. López-Valiente, Yuan Liu, Cam Mong La, Isabella Beraldo Xavier, Sean M. Hartig, Pradip Saha, et al.recovery period, the mice were randomly assigned to receive either 17β‐estradiol (E2; MedChemExpress, HY‐B0141) or vehicle control via oral gavage, administered daily at either ZT4 (corresponding to the trough of

(7) Differential Expression and Function of Arginase in Mouse Uterus During Early PregnancyInt J Mol SciMay 14, 2026Zai-Mei Wang, Qi-Man Shen, Hui-Na Luo, Hong-Yuan Yang, Jian Lu, Zeng-Ming YangSt. Louis, MO, USA). Mouse stromal cells were induced for in vitro decidualization using 10 nM E2 (HY-B0141, MedChemExpress, Monmouth Junction, NJ, USA) and 1 μM P4 as previously described [64]. Prl8a2 is a marker

(8) Mitochondrial Function Under Combined Oral Contraceptive Exposure in a Neuroblastoma Model: A Preliminary InvestigationBiomedicinesMay 7, 2026Francesco Chiara, Sarah Allegra, Francesco Maximillian Anthony Shelton Agar, Giuliana Abbadessa, Silvia De Franciamitochondrial responses. 2. Materials and Methods 2.1. Reagents and Solutions P4 (HY-N0437), E2 (HY-B0141), DNG (HY-B0084), and EE (HY-B0216) were standard-grade and purchased from MedChemExpress (Monmouth

(9) A degrader of HER2 and EGFR abolishes p95HER2 and shows robust antitumor efficacy in HER2-positive breast cancerScientific reportsApril 20, 2026Yang L, Bhattacharya A, Li Y, Peterson D, Zhang Y.fat pad using a trocar. Drinking water was supplemented with 1 μM 17β-estradiol (MedChemExpress, Cat # HY-B0141) to support PDX growth, which was changed twice weekly. Tumor volume was measured using length x width2

(10) Senescence‐Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of EndometriosisAging CellApril 1, 2026Jingchun Liu, Wuyue Han, Jianming Tang, Huanzhi Wan, Haoyu Wang, Jiaxin Peng, Wenjing Ma, Min Hu, Li HongReagents, Antibodies, and Primers All reagents were purchased from MedChemExpress, including estradiol (HY‐B0141), stigmasterol (HY‐N0131), D‐galactose (HY‐N0210), and corn oil (HY‐Y1888). Flag‐PAK4 and control plasmids

(11) Targeting a super-enhancer induced aldehyde dehydrogenase metabolic loop mitigates CDK4/6 inhibitor resistance in estrogen receptor-positive cancersNature CommunicationsMarch 27, 2026Xiaochuan Chen, Shini Liu, Dandong Luo, Dezheng Lin, Jun Liu, Huanmiao Zhan, Shuqin Chen, Peng Deng, Zhaoliang Yu(100-26, Peprotech), 500 nM A83-01 (No.2939, Tocris), 100 nM SB202190 (S1077, Selleck), 10 nM β-estradiol (HY-B0141, MedChemExpress) and 10 μM Y-27632 (M20999, AbMole). Organoids were routinely passaged by dissociation

(12) C/EBPβ dictates postmenopausal FSHβ transcription and blockade of AEP/C/EBPβ pathway alleviates osteoporosisBone ResMarch 17, 2026Zhongyun Xie, Jianming Liao, Jing Xiong, Zhenlei Zhao, Keqiang Yetreated with GnRH (10 nmol/L, Sigma Chemical Co., St. Louis, MO) or E2 (10 nmol/L, MedChemExpress, HY-B0141) for 4 h, after which the cells were lysed for WB, ChIP-PCR or RT-qPCR assay. Antibody and reagents Antibody

(13) Estrogen Production in Pancreatic Cancer Shapes a Tumor-Suppressive Stromal MicroenvironmentCancer researchFebruary 2, 2026Manoukian P, van Schie DM, van Schelt AS, Wassenaar NPM, Dings MPG, Lansbergen MF, Waasdorp C, Leite de Oliveira R, Wickenhagen WV, Heijboer AC, et al.(proliferation) or six-well plates (flow cytometry and qRT-PCR) and exposed to β-estradiol (MedChemExpress, HY-B0141) or a vehicle control for 72 hours; medium containing charcoal-stripped serum (Gibco; 12676029) was

(14) Estrogen Production in Pancreatic Cancer Shapes a Tumor-Suppressive Stromal MicroenvironmentCancer ResearchFebruary 2, 2026Paul Manoukian, Deni M. van Schie, Anne-Sophie van Schelt, Nienke P.M. Wassenaar, Mark P.G. Dings, Marjolein F. Lansbergen, Cynthia Waasdorp, Rodrigo Leite de Oliveira, Wjera V. Wickenhagen, Annemieke C. Heijboer, et al.(proliferation) or six-well plates (flow cytometry and qRT-PCR) and exposed to β-estradiol (MedChemExpress, HY-B0141) or a vehicle control for 72 hours; medium containing charcoal-stripped serum (Gibco; 12676029) was

(15) Gestational progesterone restores menstrual cycle in PCOS patients via enhancing ovary estrogen productionLife MetabolismFebruary 2, 2026Qiwen Yang, Na Kong, Jing Wu, Yan Yang, Xinge Zhang, Yuan Lin, Zhibin Hu, Guijun Yan, Haixiang Sun, Chaojun LiHY-N0437) dissolved in sesame oil (Prog group) or sesame oil alone (control group) for 21 days. E2 (MCE, HY-B0141) was dissolved in saline and injected daily i.p. for 21 days. LH, T, and E2 ELISA assays Plasma LH,

(16) Sex hormone-responsive human vaginal epithelial organoids: a novel in vitro platform for studying Chlamydia trachomatis infectionCell Communication and SignalingJanuary 24, 2026Biya Zeng, Fanxuan Zhao, Feng Zhou, Weijia Gu, Fangying Sun, Wen Lv, Guangxiao Li, Yi Zhang, Xinyu Wang, Xiang Lin, et al.hormonal stimulation, organoids were expanded in COM-W and subjected to treatment with β-estradiol (E2; HY-B0141, MedChemExpress, NJ, USA), progesterone (P4; HY-N043, MedChemExpress), and 8-bromoadenosine 3’,5’-cyclic

(17) Targeting integrin αVβ3–Ptgs2–mTOR signaling rescues bone formation in osteoporosis: from molecular mechanism toward therapyCellular & Molecular Biology LettersJanuary 6, 2026Changshun Chen, Jinyi Gu, Chenhui Yang, Fei Yang, Zirui Liu, Lei Wen, Rongjing Chen, Bin Geng, Yayi Xiamodel was established using the MC3T3-E1 cell line and primary osteoblasts, employing 17β-estradiol (HY-B0141, MCE, USA). The specific experimental procedures were as follows: (1) The MC3T3-E1 cell line and primary

(18) Hyaluronic acid-CD44 signaling from decidual stromal cells orchestrates dNK1 differentiation and immune tolerance in early pregnancyFrontiers in immunologyJanuary 1, 2026Wang D, Zhu J, Wang Q, Shi L, He Y, Jin Z, Chen W, Chen X, Chen S, Li H, et al.HY-2306), 1 μM medroxyprogesterone acetate (MedChemExpress, HY-B0469), and 10 nM estradiol (MedChemExpress, HY-B0141) for 48 hours. Successful decidualization was confirmed by the significant up-regulated expression of

(19) Targeting the CD47-HCK-LGALS9 axis disrupts proliferation-immunosuppression coupling in early-stage endometrial cancerMolecular CancerDecember 23, 2025Jingxuan Ye, Yitong Yan, Xiaoqi Sun, Qibin Wu, Yashi Shi, Maotong Zhang, Xite Lin, Yuan Ren, Xiaodan Mao, Mingyan Lin, et al.GSK5182 (#SML3150, Germany) at 10, 20, and 30 µM; progesterone (#HY-N0437, MCE, USA); and estradiol (#HY-B0141, MCE, USA). All treatments were applied for 24 h. Regulation of ERRγ expression was achieved through

(20) Estrogen receptor 1 activation suppresses microglia-derived Tnf-α signaling as a photoreceptor self-protection mechanismJournal of neuroinflammationDecember 22, 2025Li Y, Li Y, Luo J, Wang L, Yang Q, Yang Q, Duan C, Xu W, Dong Y, Kong L, et al.maximizing independent observations. After 48 h in culture, explants were treated with 10 μM E2 [31] (HY-B0141; MedChemExpress, Sollentuna, Sweden), 10 μM E2 plus 10 nM AZD9496 [32] (HY-12870; MedChemExpress), 15

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Estradiol from MedChemExpress

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Estradiol from MedChemExpress

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