EHT 1864 from Cayman Chemical

Product Specs
ItemEHT 1864
CompanyCayman Chemical
Price $1,003.00Supplier Page View Company Product Page
Catalog Number17258
FormatA crystalline solid
Research AreaAlzheimer’s Disease, Cancer, Cell Biology, Cell Migration & Metastasis, Cell Signaling, GTPases, Neurodegenerative Disorders, Neuroscience
Molecular Weight581.475449
Quantity50 mg
Purity≥98%
Storage-20
FormulaC25H27F3N2O4S • 2HCl
OriginCHN
TypeInhibitors

Add to Compare List

Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) HIV Nef-mediated WAVE2-ARP2/3 inhibition underlies CD4 + T-cell lamellipodial abnormalities and immune dysfunctionmBioMay 13, 2026Daniel C. Dunn, Jacqueline M. Crater, Perla M. Del Río Estrada, Jeffrey M. Malgady, Griffin Haas, William Klain, Maria Fernanda Torres-Ruiz, Yara Andrea Luna-Villalobos, Mauricio González-Navarro, Chris Kang, et al.(Rac1, Rac1b, Rac2, and Rac3) were inhibited by adding 20 μM EHT 1864 (Cayman Chemical Company, Catalog #17258). Pak1/2 was inhibited by adding 50 μM IPA3 (Cayman Chemical Company, Catalog #14759 ). ARP2/3 was inhibited

(2) KCNA2 variants cause dilated cardiomyopathy, obesity and sleep apnea through RAC-ERK pathwayEMBO Molecular MedicineFebruary 24, 2026Prasanth Chimata, Sahil Lall, Tarmo Annilo, M K Mathew, Andres Metspalu, Jayaprakash Shenthar, Perundurai S DhandapanyH9c2 cells, we utilized a well-known RAC1 inhibitor EHT1864 (Shutes et al, 2007) (Cayman Chemical, 17258). At 40 h post-transfection, the cells were cultured in DMEM with 2% FBS for 6 h before treatment with

(3) Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancerCancer CellSeptember 8, 2025Yijuan Zhang, Li Ling, Rabi Murad, Swetha Maganti, Ambroise Manceau, Hannah A. Hetrick, Madelaine Neff, Cheska Marie Galapate, Shea F. Grenier, Florent Carrette, et al.Bovine Serum, Fraction V",Sigma-Aldrich,"Cat# 126609, CAS: 9048-46-8" EHT 1864,Cayman Chemical,"Cat# 17258, CAS: 754240-09-0" SCH772984,Selleckchem,"Cat# S7101, CAS: 942183-80-4" Trametinib,Selleckchem,"Cat#

(4) Differential Effects of Confinement on the Dynamics of Normal and Tumor-Derived Pancreatic Ductal OrganoidsACS Applied Bio MaterialsDecember 16, 2024Jonah M. Rosas, Joseph P. Campanale, Jacob L. Harwood, Lufei Li, Rachel Bae, Shujun Cheng, Julia M. Tsou, Kathi M. Kaiser, Dannielle D. Engle, Denise J. Montell, et al.cat.#19545–26–7, 1 μM), forskolin (MechChem Express, cat.#HY-15371, 5 μM), ETH-1864 (Cayman Chemicals, cat.#17258, 20 μM), or VX-11e (Selleckchem, cat.#S7709, 10 μM). Organoids were imaged using a Leica DMi8 Widefield

(5) Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulenceiScienceJune 21, 2024Masaki Ishii, Yasuhiko Matsumoto, Tsuyoshi Yamada, Hideko Uga, Toshiaki Katada, Shinya Ohataproteins" ,, NSC23766,Selleck Chemicals,Cat#S8031 MBQ-167,Selleck Chemicals,Cat#S8749 EHT1864,Cayman Chemical Company,Cat#17258 ML-141,Cayman Chemical Company,Cat#18496 EHop-016,Cayman Chemical Company,Cat#21557 ZCL-278,Cayman Chemical Company

(6) HIV-1 Mediated Cortical Actin Disruption Mirrors ARP2/3 Defects Found in Primary T Cell ImmunodeficienciesbioRxivFebruary 19, 2024Jacqueline M. Crater, Daniel Dunn, Douglas F. Nixon, Robert L. Furler O’Brien(Rac1, Rac1b, Rac2, and Rac3) were inhibited by adding 20μM EHT 1864 (Cayman Chemical Company, Catalog #17258). Pak1/2 were inhibited by adding 50μM IPA-3 (Cayman Chemical Company, Catalog #14759). ARP2/3 was inhibited

(7) Self-assembly of mesoscale collagen architectures and applications in 3D cell migrationActa BiomaterialiaJanuary 1, 2023Chang Liu, Ryan Y. Nguyen, Gabriela A. Pizzurro, Xingjian Zhang, Xiangyu Gong, Alejandro Rossello Martinez, Michael Makinhibitor CK666 (Abcam, ab141231), 100 μM Rac1 inhibitor NSC23766, 20 μM Rac1 inhibitor EHT1864 (Cayman, 17258) were used. Fresh media mixed with specific drugs were prepared right before the experiment and replaced

(8) Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesisNature communicationsJuly 15, 2022Darp R, Vittoria MA, Ganem NJ, Ceol CJ.(HY-18972, MCE), Centrinone 300 nM (5687, Tocris), NSC2366 5 µM (13196, Cayman Chem), EHT1864 5 µM (17258, Cayman Chem), LPA 1 µM (BML-LP100-0005, Enzo), S1P 1 µM (62570, Cayman Chem), Dihydrocytochalasin B

(9) Prominin-1 Modulates Rho/ROCK-Mediated Membrane Morphology and Calcium-Dependent Intracellular Chloride FluxScientific ReportsDecember 1, 2019Akiko Hori et al.#030-17551), nocodazole (SIGMA; #M1404), Simvastatin (Cayman chemical; #10010344), EHT1864 (Cayman chemical; #17258), ZCL278 (TOCRIS; #4794), Y-27632 (Wako, Japan; #251-00511), C3 (Cytoskeleton,Inc; #CT04). LY294002

(10) Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory ActivityImmunityNovember 20, 2018Shi H, Liu C, Tan H, Li Y, Nguyen TM, Dhungana Y, Guy C, Vogel P, Neale G, Rankin S, et al.Recombinant Proteins" 7-AAD,Sigma-Aldrich,Cat# A9400 EHT-1864 (Rac inhibitor),Cayman Chemical,Cat# 17258; CAS: 754240-09-0 EHop-016 (Rac inhibitor),Tocris,Cat# 6248; CAS: 1380432-32-5 Cytochalasin D (actin

(11) Key role for Rac in the early transcriptional response to extracellular matrix stiffness and stiffness-dependent repression of ATF3Journal of cell scienceJanuary 1, 0001"Dang I, Brazzo JA, Bae Y, Assoian RK."mg/ml BSA and incubated in suspension for 30 min at 37°C in 10% CO2 and 10 µM EHT1864 (3872, Tocris or 17258, Cayman Chemical) or 2 µg/ml CT04 (CT04-A, Cytoskeleton). Stock solutions of EHT1864 and CT04 were generated

Be the First to Write a Review!

EHT 1864 from Cayman Chemical

Description

Cayman Chemical

Citations (11)

Reviews

EHT 1864 from Cayman Chemical

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map