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Protein Biochemistry
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RG7388
RG7388 from Cayman Chemical
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Citations:
(2)
Supplier Page
Supplier Page from
Cayman Chemical for
RG7388
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Description
A selective MDM2 inhibitor that blocks the binding of MDM2 to p53 (IC50 = 30 nM); activates the p53 pathway in SJSA1 osteosarcoma cells and inhibits the growth of xenografts in nude mice
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
RG7388
Company
Cayman Chemical
Price
$621.00
Supplier Page
View Company Product Page
Catalog Number
21532
Format
A crystalline solid
Research Area
Apoptosis, Cancer, Cell Death, Cell Signaling, Multidrug Resistance, p53, p53 Signaling, Transcription Factors
Molecular Weight
616.5
Quantity
25 mg
Purity
≥98%
Storage
-20
Formula
C31H29Cl2F2N3O4
Origin
CHN
Type
Inhibitors
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (2)
(1)
Synergistic MDM2-STAT3 Inhibition Demonstrates Strong Anti-Leukemic Efficacy in Acute Lymphoblastic Leukemia
International Journal of Molecular Sciences
September 5, 2025
Erhan Aptullahoglu, Emrah Kaygusuz
inhibitor
, also known as napabucasin) were used in this study. Both
inhibitors
, obtained as powders (
Cayman
#
21532
for
RG7388
and
Cayman
#
22255
for BBI608), were dissolved in DMSO (dimethyl sulfoxide) (Serva #20385.02)
(2)
Chemopreventive Agent 3,3'-Diindolylmethane Inhibits MDM2 in Colorectal Cancer Cells
International journal of molecular sciences
June 30, 2020
Gao X, Liu J, Cho KB, Kedika S, Guo B.
HCT-116c2. 4.2. Drugs and Chemicals DIM (cat. # D3232, LKT Laboratories, St. Paul, MN, USA), RG-7388 (cat. #
21532
,
Cayman
, Ann Arbor, MI, USA), and Nutlin-3a (cat. # 44151,
Millipore
, Billerica, MA, USA) were dissolved/diluted
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RG7388 from Cayman Chemical
Supplier Page
View Company Product Page
$621.00
Product Specs
Company Info
Citations
Reviews
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