HDAC developer (2X) from BPS Bioscience, Inc.

Product Specs
ItemHDAC developer (2X)
CompanyBPS Bioscience, Inc.
Price $230.00Supplier Page View Company Product Page
Catalog Number50030
Quantity6 ml
TypeAssay Kit Component
ApplicationsStudy of HDAC kinetics, regulation and inhibitor sensitivity. Ideal for drug discovery and HTS applications and cell-based HDAC assays
FormatAqueous buffer solution

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BPS Bioscience, Inc.

6405 Mira Mesa Blvd

Suite 100

San Diego, CA 92121

United States

Phone: 858-202-1401

Email: sales-team@bpsbioscience.com

Company Profile

Website: https://bpsbioscience.com/

(1) Cyclic Tetrapeptide HDAC Inhibitors with Improved Plasmodium falciparum Selectivity and Killing ProfileACS Infectious DiseasesOctober 8, 2021Jennifer E. Collins, Jin Woo Lee, Monica J. Bohmer, Joshua D. Welden, Arash K. Arshadi, Lin Du, Robert H. Cichewicz, Debopam Chakrabartifluorogenic HDAC substrate 3 (Cat # 50037), assay buffer (Cat # 50031), and assay developer (BPS # 50030). Reactions were incubated in 384-well plates at 37°C for 2 h with inhibitor dilutions using no-enzyme

(2) Synthesis and pharmacological evaluation of pomalidomide derivatives useful for sickle cell disease treatmentBioorganic ChemistrySeptember 1, 2021Thais Regina Ferreira de Melo et al.at 3 nM and 30 nM. After enzymatic reactions, 50 μL of 2x HDAC Developer ((BPS Bioscience, catalog #50030) was added to each well for the HDAC enzymes and the plate was incubated at room temperature for an

(3) Molecular design, synthesis and in vitro biological evaluation of thienopyrimidineâ€“hydroxamic acids as chimeric kinase HDAC inhibitors: a challenging approach to combat cancerJournal of Enzyme Inhibition and Medicinal ChemistryJune 30, 2021Mona M. Abdel-Atty, Nahla A. Farag, Rabah A. T. Serya, Khaled A. M. Abouzid, Samar Mowafy(BPS#50037), HDAC Assay Buffer (BPS catalogue number 50031) and HDAC Assay Developer (BPS catalogue number 50030) was used in testing. TSN is also used as a reference compound purchased from Selleckcom.com (#S1045). 5.2.2.2.

(4) A synthetic combinatorial approach to disabling deviant Hedgehog signalingScientific ReportsDecember 1, 2018C-W. Fan, N. Yarravarapu, H. Shi, O. Kulak, J. Kim, C. Chen, L. Luman HDAC enzyme (#50051-11) and a test compound. After enzymatic reactions, 50 μl of HDAC Developer (#50030) was added to each well and the plate was incubated at room temperature for an additional 20 mins. Fluorescence

(5) Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitorsNature communicationsJanuary 4, 2018Kalin JH, Wu M, Gomez AV, Song Y, Das J, Hayward D, Adejola N, Wu M, Panova I, Chung HJ, et al.aliquots were quenched at 0, 5, 10, 20, 40, 120 min with an equal volume of Developer (BPS Bioscience, 50030) and fluorescence was measured as described in the HDAC1 inhibition assay. Prolonged HDAC inhibition

(6) Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1Journal of Medicinal ChemistrySeptember 14, 2017Allie Y. Chen et al.plate was incubated at 37 °C for 30 min. HDAC assay developer (50 μL, BPS Bioscience, catalogue no. 50030) was added to each well and the plate incubated for 15 min at room temperature. The fluorescence was

(7) Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11Nature chemical biologyMay 1, 2017Li J, Yakushi T, Parlati F, Mackinnon AL, Perez C, Ma Y, Carter KP, Colayco S, Magnuson G, Brown B, et al.incubated at 37 °C for 30 min. At this point, HDAC assay developer (50 μL, BPS Bioscience catalog #50030) was added to each well and the plate was incubated for 15 min at room temperature. The fluorescence

(8) Discovery of an Inhibitor of the Proteasome Subunit Rpn11Journal of Medicinal ChemistryFebruary 23, 2017Christian Perez, Jing Li, Frank Parlati, Matthieu Rouffet, Yuyong Ma, Han-Jie Zhou, Andrew L. Mackinnon, Tsui-Fen Chou, Raymond J. Deshaies, Seth M. Cohenincubated at 37 °C for 30 min. At this point, HDAC assay developer (50 μL, BPS Bioscience catalog #50030) was added to each well and the plate was incubated for 15 min at room temperature. The fluorescence

(9) A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer’s Disease MiceNeuropsychopharmacologyJanuary 1, 2017Mar Cuadrado-Tejedor et al.Cuadrado-Tejedor et al 526 stopped with 50 μl of lysine assay developer (BPS Biosciences, Cat. no. 50030). After incubation for 20 min at room temperature, the fluorescence of each well was measured at 355

(10) Investigating the Selectivity of Metalloenzyme Inhibitors in the Presence of Competing MetalloproteinsChemMedChemOctober 1, 2015Yao Chen, Seth M. Cohenplate was incubated at 37 °C for 30 min. HDAC assay developer (50 μL, BPS Bioscience, catalogue no. 50030) was then added to each well and the plate incubated for 15 min at room temperature. The fluorescence

(11) Discovery of a Novel HDAC2 Inhibitor by a Scaffold-Merging Hybrid QueryCombinatorial Chemistry & High Throughput ScreeningSeptember 3, 2015Nikita Basant, Xionghao Lin, Terry-Elinor Reid, Pradeep K Karla, Xiang S Wangsame temperature for another 30 minutes. The HDAC assay developer (50 μL, BPS Bioscience, Catalog No. 50030) was then added to each well and the plate was incubated for another 15 minutes. The fluorescence was

(12) Investigating the Selectivity of Metalloenzyme InhibitorsJournal of Medicinal ChemistryOctober 24, 2013Joshua A. Day, Seth M. Cohenthe plate was incubated at 37 °C for 30 min. HDAC assay developer (50 μL, BPS Bioscience, Catalog No. 50030) was added to each well and the plate incubated for 15 min at room temperature. The fluorescence was

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HDAC developer (2X) from BPS Bioscience, Inc.

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BPS Bioscience, Inc.

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HDAC developer (2X) from BPS Bioscience, Inc.

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