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Caspase-3 Substrates (Fluorescent)
Ac-DEVD-AMC
Ac-DEVD-AMC from Enzo Life Sciences, Inc.
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Citations:
(3)
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Enzo Life Sciences, Inc. for
Ac-DEVD-AMC
Supplier Page
Description
Fluorogenic substrate for caspase-3 with Km=9.7µM. Also a substrate for caspase-1, -4, -7 and -8. The peptide sequence is based on the PARP cleavage site Asp216 for caspase-3. Ex.: 340-360nm, Em.: 440-460nm
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Ac-DEVD-AMC
Company
Enzo Life Sciences, Inc.
Price
$163.00
Get Pricing
Get Quote for this Product
Catalog Number
ALX-260-031-M005
Molecular Weight
675.7
Purity
≥97% (HPLC)
Format
Lyophilized
Formula
C
30
H
37
N
5
O
13
Quantity
5 mg
Type
Peptide
Molecule Name
Ac-DEVD-AMC
Sequence
Ac-Asp-Glu-Val-Asp-AMC (AMC = 7-Amino-4-methylcoumarin)
Specifications/Features
Caspase substrate
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Enzo Life Sciences, Inc.
10 Executive Blvd.
Farmingdale
,
NY
11735
United States
Phone
: 800-942-0430
Fax: 610-941-9252
Company Profile
Website:
www.enzo.com
Citations (3)
(1)
IRE1α overexpression in malignant cells limits tumor progression by inducing an anti-cancer immune response
Oncoimmunology
January 1, 2022
Martinez-Turtos A, Paul R, Grima-Reyes M, Issaoui H, Krug A, Mhaidly R, Bossowski JP, Chiche J, Marchetti S, Verhoeyen E,
et al
.
(CellStar) in the presence of 0.2 mmol/L of the caspase-3 substrate
Ac-DEVD-AMC
(
Enzo
LifeScience,
ALX-260-031-M005
) diluted in the lysis buffer containing 10 mmol/L
DTT
. Caspase activity was determined either in the
(2)
Histone chaperone FACT is essential to overcome replication stress in mammalian cells
Oncogene
July 1, 2020
Prendergast L, Hong E, Safina A, Poe D, Gurova K.
sucrose, 0.1% CHAPS, 1 mM EDTA, 2 mM dithiothreitol, and 50 μM caspase-3/7 substrate ((
Ac-DEVD-AMC
) Cat#
ALX-260-031-M005
;
Enzo Life Sciences
, Farmingdale, NY) were added. Basal activity was measured at an excitation wavelength
(3)
K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation
Nature communications
September 13, 2019
Tang Y, Tu H, Zhang J, Zhao X, Wang Y, Qin J, Lin X.
mTNFα in the presence of 5 μM SytoxGreen (
Invitrogen
,
S34860
) or 20 μM Ac-DEVD-MCA (
Enzo Life Science
,
ALX-260-031-M005
). SytoxGreen intensity and Caspase3 activation were measured at intervals of 1 h using a Fluostar Omega
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Ac-DEVD-AMC from Enzo Life Sciences, Inc.
Get Pricing
Get Quote for this Product
$163.00
Product Specs
Company Info
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