Recombinant Mouse BAFF/BLyS/TNFSF13B Protein, CF 8876-BF-010/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse BAFF/BLyS/TNFSF13B Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $291.00Supplier Page View Company Product Page
Catalog Number8876-BF-010/CF
Size10 ug
FormatLyophilized from a 0.2 µm filtered solution in MOPS, NaCl and TCEP
Purity>85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 19-23 kDa (monomer) & 38-47 kDa (non-reducible dimer), reducing conditions
Theoretical: 21 kDa
SpeciesMouse
Molecule NameBAFF/BLyS/TNFSF13B
NCBI Full Gene Nametumor necrosis factor (ligand) superfamily, member 13b
NCBI Gene AliasesBLyS, TALL1, THANK, TNFSF20, zTNF4, Tnlg7a, TALL-1, D8Ertd387e, BAFF
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Mouse BAFF/BLyS/TNFSF13B Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) TRAF2/3 deficient B cells resist DNA damage-induced apoptosis via NF-κB2/XIAP/cIAP2 axis and IAP antagonist sensitizes mutant lymphomas to chemotherapeutic drugsCell death & diseaseSeptember 8, 2023Vashisht M, Ge H, John J, McKelvey HA, Chen J, Chen Z, Wang JH.(09655, STEMCELL) supplemented with 10% FBS and antibiotics in presence or absence of mouse IL-4 or BAFF (8876-BF-010/CF, R&D system). Medium was replenished every 3–5 days. Cells were observed up to 20 weeks. Cells that

(2) BAFF induces CXCR5 expression during B cell differentiation in bone marrowBiochemistry and biophysics reportsJuly 1, 2023Koizumi H, Fujii W, Sanjoba C, Goto Y.Fisher Scientific) and then stimulated with 100 ng/ml of recombinant murine BAFF (rmBAFF) (R&D SYSTEMS #8876-BF-010/CF), 100 ng/ml of rmTNF-α (R&D SYSTEMS #410-MT-010), 50 ng/ml of rmIL-6 (R&D SYSTEMS #406-ML-005), or medium

(3) BAFF and APRIL counterregulate susceptibility to inflammation-induced preterm birthCell reportsApril 25, 2023Doll JR, Moreno-Fernandez ME, Stankiewicz TE, Wayland JL, Wilburn A, Weinhaus B, Chougnet CA, Giordano D, Cappelletti M, Presicce P, et al.recombinant proteins","Chemicals, peptides, and recombinant proteins" ,, Recombinant BAFF,R&D Systems,Cat# 8876-BF-010/CF Recombinant APRIL,R&D Systems,Cat# 7907-AP-010/CF LPS (E. coli 0111:B4),Invivogen,Cat# vac-3pelps M-CSF,Biolegend,Cat#

(4) Generation of B-cell-based cellular vaccine for cancer in murine modelsSTAR protocolsApril 20, 2023Hou D, Katz JL, Lee-Chang C.peptides, and recombinant proteins" ,, Recombinant Mouse BAFF/BLyS/TNFSF13B Protein,R&D Systems,Cat# 8876-BF-010/CF Recombinant Murine IFN-y,Peprotech,Cat# 315-05 Recombinant Murine IL2,Peprotech,Cat# 212-12 MEM non-essential

(5) Role of B Cell-Activating Factor in Fibrosis Progression in a Murine Model of Non-Alcoholic SteatohepatitisInternational journal of molecular sciencesJanuary 28, 2023Kanemitsu-Okada K, Abe M, Nakamura Y, Miyake T, Watanabe T, Yoshida O, Koizumi Y, Hirooka M, Tokumoto Y, Matsuura B, et al.

(6) Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin lociNature communicationsApril 5, 2022Satofuka H, Abe S, Moriwaki T, Okada A, Kazuki K, Tanaka H, Yamazaki K, Hichiwa G, Morimoto K, Takayama H, et al.

(7) Regulation of B cell functions by S-nitrosoglutathione in the EAE modelRedox biologySeptember 1, 2021Kim J, Islam SMT, Qiao F, Singh AK, Khan M, Won J, Singh I.

(8) Circulating CD138 enhances disease progression by augmenting autoreactive antibody production in a mouse model of systemic lupus erythematosusThe Journal of biological chemistrySeptember 1, 2021Liu L, Akkoyunlu M.

(9) A BAFF/APRIL axis regulates obesogenic diet-driven weight gainNature communicationsMay 18, 2021Chan CC, Harley ITW, Pfluger PT, Trompette A, Stankiewicz TE, Allen JL, Moreno-Fernandez ME, Damen MSMA, Oates JR, Alarcon PC, et al.

(10) NR4A nuclear receptors restrain B cell responses to antigen when second signals are absent or limitingNature immunologyOctober 1, 2020Tan C, Hiwa R, Mueller JL, Vykunta V, Hibiya K, Noviski M, Huizar J, Brooks JF, Garcia J, Heyn C, et al.

(11) BCR-Induced Ca²⁺ Signals Dynamically Tune Survival, Metabolic Reprogramming, and Proliferation of Naive B CellsCell reportsApril 14, 2020Berry CT, Liu X, Myles A, Nandi S, Chen YH, Hershberg U, Brodsky IE, Cancro MP, Lengner CJ, May MJ, et al.

(12) E3 Ubiquitin Ligase Fbw7 Regulates the Survival of Mature B CellsJournal of immunology (Baltimore, Md. : 1950)March 15, 2020Ramezani-Rad P, Leung CR, Apgar JR, Rickert RC.

(13) Etanercept Inhibits B Cell Differentiation by Regulating TNFRII/TRAF2/NF-κB Signaling Pathway in Rheumatoid ArthritisFrontiers in pharmacologyJanuary 1, 2020Cai XY, Zhu Y, Wang C, Tang XY, Han L, Shu JL, Zhang XZ, Liang FQ, Ge JR, Xu L, et al.

(14) Tumor-Derived Thymic Stromal Lymphopoietin Expands Bone Marrow B-cell Precursors in Circulation to Support MetastasisCancer researchNovember 15, 2019Ragonnaud E, Moritoh K, Bodogai M, Gusev F, Garaud S, Chen C, Wang X, Baljinnyam T, Becker KG, Maul RW, et al.

(15) MicroRNA-29a Counteracts Glucocorticoid Induction of Bone Loss through Repressing TNFSF13b Modulation of OsteoclastogenesisInternational journal of molecular sciencesOctober 17, 2019Wu RW, Lian WS, Chen YS, Kuo CW, Ke HC, Hsieh CK, Wang SY, Ko JY, Wang FS.

(16) Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responsesNature communicationsJuly 3, 2019Jiang Y, Li C, Wu Q, An P, Huang L, Wang J, Chen C, Chen X, Zhang F, Ma L, et al.

(17) Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activationeLifeJune 3, 2019Bolger-Munro M, Choi K, Scurll JM, Abraham L, Chappell RS, Sheen D, Dang-Lawson M, Wu X, Priatel JJ, Coombs D, et al.

(18) TACI expression and plasma cell differentiation are impaired in the absence of functional IκBNSImmunology and cell biologyMay 1, 2019Khoenkhoen S, Erikson E, Ádori M, Stark JM, Scholz JL, Cancro MP, Pedersen GK, Karlsson Hedestam GB.

(19) Integrated B Cell, Toll-like, and BAFF Receptor Signals Promote Autoantibody Production by Transitional B CellsJournal of immunology (Baltimore, Md. : 1950)December 1, 2018Du SW, Jacobs HM, Arkatkar T, Rawlings DJ, Jackson SW.

(20) Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupusNature communicationsSeptember 28, 2018Sang A, Danhorn T, Peterson JN, Rankin AL, O'Connor BP, Leach SM, Torres RM, Pelanda R.

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BAFF/BLyS/TNFSF13B Protein

BAFF/BLyS/TNFSF13B Protein

BAFF/BLyS/TNFSF13B Protein

Recombinant Mouse BAFF/BLyS/TNFSF13B Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse BAFF/BLyS/TNFSF13B Protein, CF from R&D Systems, a Bio-Techne Brand

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