Lymphotoxin α1/β2 Protein 8884-LY-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemLymphotoxin α1/β2 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number8884-LY-025
Quantity25 ug
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 65-76 kDa, reducing conditions
Theoretical: 61 kDa
SpeciesHuman
Molecule NameLymphotoxin
Source/Expression SystemHEK293-derived Recombinant Human Lymphotoxin alpha1/beta2 Protein
Brand/TrademarkR&D Systems, a Bio-Techne Brand
NCBI Full Gene Namelymphotoxin alpha, lymphotoxin beta
NCBI Gene AliasesLT, TNFB, TNFC, TNFSF3, p33, TNFSF1, TNLG1C, TNLG1E
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Interference with LTβR signaling by tick saliva facilitates transmission of Lyme disease spirochetesProceedings of the National Academy of SciencesNovember 22, 2022Lin Jin, Bao-Gui Jiang, Yizhu Yin, Jingya Guo, Jia-Fu Jiang, Xiaopeng Qi, Gary Crispell, Shahid Karim, Wu-Chun Cao, Ren Laiof BSK-H medium (20 μL/mg tissue) after rapid surface sterilization. Immunoblot Analysis. LTαβ2 (8884-LY-025, R&D Systems) and anti-LTβR (ab10493, Abcam) were used for LTβR dimerization analysis as in our previous

(2) Polycomb Repressive Complex 2 Regulates Genes Necessary for Intestinal Microfold Cell (M Cell) DevelopmentCellular and molecular gastroenterology and hepatologyJanuary 1, 2021George JJ, Oittinen M, Martin-Diaz L, Zapilko V, Iqbal S, Rintakangas T, Arrojo Martins FT, Niskanen H, Katajisto P, Kaikkonen MU, et al.

(3) Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptorCell communication and signaling : CCSNovember 4, 2020Maksymowicz M, Miączyńska M, Banach-Orłowska M.

(4) Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritisArthritis research & therapyFebruary 26, 2018Hähnlein JS, Nadafi R, de Jong T, Ramwadhdoebe TH, Semmelink JF, Maijer KI, Zijlstra IA, Maas M, Gerlag DM, Geijtenbeek TBH, et al.

(5) Development of intestinal M cells and follicle-associated epithelium is regulated by TRAF6-mediated NF-κB signalingThe Journal of experimental medicineFebruary 5, 2018Kanaya T, Sakakibara S, Jinnohara T, Hachisuka M, Tachibana N, Hidano S, Kobayashi T, Kimura S, Iwanaga T, Nakagawa T, et al.

(6) TNFSF14 (LIGHT) Exhibits Inflammatory Activities in Lung Fibroblasts Complementary to IL-13 and TGF-βFrontiers in immunologyJanuary 1, 2018da Silva Antunes R, Mehta AK, Madge L, Tocker J, Croft M.

(7) Eudesmane-Type Sesquiterpene Lactones Inhibit Nuclear Translocation of the Nuclear Factor κB Subunit RelB in Response to a Lymphotoxin β StimulationBiological & pharmaceutical bulletinJanuary 1, 2017Quach HT, Kondo T, Watanabe M, Tamura R, Yajima Y, Sayama S, Ando M, Kataoka T.

(8) Bimodal Expansion of the Lymphatic Vessels Is Regulated by the Sequential Expression of IL-7 and Lymphotoxin α1β2 in Newly Formed Tertiary Lymphoid StructuresJournal of immunology (Baltimore, Md. : 1950)September 1, 2016Nayar S, Campos J, Chung MM, Navarro-Núñez L, Chachlani M, Steinthal N, Gardner DH, Rankin P, Cloake T, Caamaño JH, et al.

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Lymphotoxin α1/β2 Protein from R&D Systems, a Bio-Techne Brand

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Specifications/Features

R&D Systems, a Bio-Techne Brand

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Lymphotoxin α1/β2 Protein from R&D Systems, a Bio-Techne Brand

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