IL-15 Protein 247-ILB-005/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-15 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $311.00Supplier Page View Company Product Page
Catalog Number247-ILB-005/CF
Size5 ug (also 25 ug, 500 ug)
FormatLyophilized from a 0.2 µm filtered solution in PBS
SpeciesHuman
Molecule NameIL-15
Source/Expression SystemE. coli-derived Recombinant Human IL-15 Protein, CF
NCBI Full Gene Nameinterleukin 15
NCBI Gene AliasesIL-15
ApplicationsBioactivity
Conjugate/TagUnconjugated
Purity>97%, by SDS-PAGE with silver staining
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 5 ug (also 25 ug, 500 ug)

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Class I HDAC inhibition enhances the stem-like memory properties of CRISPR-engineered CAR T cells in neuroblastomaMol Ther OncolJune 18, 2026Dan Cappabianca, Mahmoud Toulany, Seth Zima, Amanda Shea, Jolanta Vidugiriene, Anthony Lauer, Kayla Sylvester, Varun Gnanasekar, Sean Foster, Rithvik Turaga, et al.(IL-7) (10 ng/mL; cat. no. 207-IL-005/CF; Bio-Techne, Minneapolis, MN) and IL-15 (10 ng/mL; cat. no. 247-ILB-005/CF; Bio-Techne, Minneapolis, MN) and maintained at 37°C in 5% CO2 as previously described.14,31 CAR T cells

(2) Dynamics of checkpoint receptors in γδ T cell subsets are associated with clinical response during anti-PD-1 immunotherapiesEMBO Molecular MedicineNovember 27, 2025Elisa Catafal-Tardos, Lola Dachicourt, Maria Virginia Baglioni, Marcelo Gregorio Filho Fares da Silva, Davide Secci, Marco Donia, Anders Handrup Kverneland, Inge Marie Svane, Vasileios BekiarisStreptomycin,Gibco,15140-122 (E)-4-hydroxy-3-methylbut-2-enyl pyrophosphate (HMBPP),Cayman Chemical,154-13580-500 Recombinant human IL-15,Biotechne,247-ILB-005/CF Recombinant human IL-7,Biotechne,207-IL-010/CF Recombinant human IL-2,Biolegend,589104 Abrocitinib,Sigma-Aldrich,1622902-68-4 NSC33994,Sigma-Aldrich,82058-16-0 Tofacitinib

(3) Low-dose radiation by radiopharmaceutical therapy enhances GD2 TRAC-CAR T cell efficacy in localized neuroblastomaSci AdvJune 4, 2025Quaovi H. Sodji, Amanda Shea, Dan Cappabianca, Matthew H. Forsberg, Jens C. Eickhoff, Malick Bio Idrissou, Andy S. Ollendorff, Ohyun Kwon, Irene M. Ong, Reinier Hernandez, et al.supplemented with IL-7 (10 ng/ml; cat. no. 207-IL-005/CF; BioTechne) and IL-15 (10 ng/ml; cat. no. 247-ILB-005/CF; BioTechne) and maintained at 37°C in 5% CO2 (13). In vitro dosimetry In vitro dosimetry studies were

(4) Efficient Nonviral Integration of Large Transgenes into Human T Cells Using Cas9-CLIPTMolecular Therapy Methods & Clinical DevelopmentMarch 13, 2025Anna Tommasi, Dan Cappabianca, Madison Bugel, Kirstan Gimse, Karl Lund-Peterson, Hum Shrestha, Denis Arutyunov, James A. Williams, Seshidhar Reddy Police, Venkata Indurthi, et al.ng/mL IL-7 (catalog no. 207-IL-005/CF, BioTechne, Minneapolis, MN) and 10 ng/mL IL-15 (catalog no. 247-ILB-005/CF, BioTechne) and stimulated with T cell TransAct (10 μL for each mL of culture, catalog no. 130-111-160,

(5) Transcriptional and methylation outcomes of didehydro-cortistatin A use in HIV-1-infected CD4+ T cellsLife Science AllianceOctober 1, 2024Luisa P Mori, Michael J Corley, Andrew T McAuley, Alina Pang, Thomas Venables, Lishomwa C Ndhlovu, Matthew E Pipkin, Susana T Valente(#11131D; Gibco) in the presence of 6 ng/ml IL-2 (MACS, #130-097-748; Miltenyi Biotec), 36 ng/ml IL-7 (#247ILB005CF; R&D Systems), and 36 ng/ml IL-15 (#207IL005CF; R&D Systems). The cells were cultured in RPMI 1640 media

(6) Refined analytical pipeline for the pharmacodynamic assessment of T-cell responses to vaccine antigensFrontiers in ImmunologyApril 24, 2024Michail Angelos Pavlidis, Nadia Viborg, Mads Lausen, Birgitte Rønø, Daniela Kleine-KohlbrecherX-VIVO 15 + 5% HS supplemented with the cytokines interleukin (IL)-15 (10 ng/ml, R&D Systems, cat. #247-ILB-005/CF) and IL-21 (50 ng/ml, R&D Systems, cat. #8879-IL-010/CF). Short peptides (8mers or 9mers) were diluted

(7) NL-201 Upregulates MHC-I Expression and Intratumoral T-cell Receptor Diversity, and Demonstrates Robust Antitumor Activity as Monotherapy and in Combination with PD-1 BlockadeCancer immunology researchJuly 5, 2023Mortales C, Dutzar B, Chen J, Chen A, Huard J, Walkey C, Swanson R.

(8) TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastomaActa neuropathologica communicationsMay 8, 2023Menevse AN, Ammer LM, Vollmann-Zwerenz A, Kupczyk M, Lorenz J, Weidner L, Hussein A, Sax J, Mühlbauer J, Heuschneider N, et al.

(9) Identification of T Cell Receptors Targeting a Neoantigen Derived from Recurrently Mutated FGFR3CancersFebruary 6, 2023Tate T, Matsumoto S, Nemoto K, Leisegang M, Nagayama S, Obama K, Nakamura Y, Kiyotani K.

(10) DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cellsScience advancesAugust 26, 2022Michaels YS, Edgar JM, Major MC, Castle EL, Zimmerman C, Yin T, Hagner A, Lau C, Hsu HH, Ibañez-Rios MI, et al.

(11) Detection of early seeding of Richter transformation in chronic lymphocytic leukemiaNature medicineAugust 1, 2022Nadeu F, Royo R, Massoni-Badosa R, Playa-Albinyana H, Garcia-Torre B, Duran-Ferrer M, Dawson KJ, Kulis M, Diaz-Navarro A, Villamor N, et al.

(12) Natural killer cell-mediated ADCC in SARS-CoV-2-infected individuals and vaccine recipientsEuropean journal of immunologyAugust 1, 2022Hagemann K, Riecken K, Jung JM, Hildebrandt H, Menzel S, Bunders MJ, Fehse B, Koch-Nolte F, Heinrich F, Peine S, et al.

(13) Novel IL-15 dendritic cells have a potent immunomodulatory effect in immunotherapy of multiple myelomaTranslational oncologyJune 1, 2022Chu TH, Vo MC, Lakshmi TJ, Ahn SY, Kim M, Song GY, Yang DH, Ahn JS, Kim HJ, Jung SH, et al.

(14) The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma CellsCancersMarch 11, 2022Sekhri P, Ledezma DK, Shukla A, Sweeney EE, Fernandes R.

(15) Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphomaNature communicationsSeptember 22, 2021Liang HC, Costanza M, Prutsch N, Zimmerman MW, Gurnhofer E, Montes-Mojarro IA, Abraham BJ, Prokoph N, Stoiber S, Tangermann S, et al.

(16) Deciphering the biology of KIR2DL3⁺ T lymphocytes that are associated to relapse in haploidentical HSCTScientific reportsAugust 4, 2021David G, Willem C, Legrand N, Djaoud Z, Mérieau P, Walencik A, Guillaume T, Gagne K, Chevallier P, Retière C.

(17) Correction of murine sickle cell disease by allogeneic haematopoietic cell transplantation with anti-3rd party veto cellsBone marrow transplantationAugust 1, 2021Singh AK, Schetzen E, Yadav SK, Lustig EB, Liu WH, Yadav RK, Gale RP, McGinnis K, Reisner Y.

(18) Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ARTPLoS pathogensAugust 1, 2021Pino M, Pereira Ribeiro S, Pagliuzza A, Ghneim K, Khan A, Ryan E, Harper JL, King CT, Welbourn S, Micci L, et al.

(19) Generation of glucocorticoid-resistant SARS-CoV-2 T cells for adoptive cell therapyCell reportsJuly 20, 2021Basar R, Uprety N, Ensley E, Daher M, Klein K, Martinez F, Aung F, Shanley M, Hu B, Gokdemir E, et al.

(20) Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targetingNature communicationsJuly 16, 2021Bear AS, Blanchard T, Cesare J, Ford MJ, Richman LP, Xu C, Baroja ML, McCuaig S, Costeas C, Gabunia K, et al.

Be the First to Write a Review!

IL-15 Protein

IL-15 Protein

IL-15 Protein

IL-15 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (171)

Reviews

IL-15 Protein from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map