Recombinant Mouse LIF Protein 8878-LF-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse LIF Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $328.00Supplier Page View Company Product Page
Catalog Number8878-LF-025
Size25 ug
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>95%, by SDS-PAGE with silver staining
Molecular WeightObserved: 20 kDa, reducing conditions
Theoretical: 20 kDa
Conjugate/TagUnconjugated
SpeciesMouse
Molecule NameLIF
Source/Expression SystemE. coli-derived Recombinant Mouse LIF Protein
NCBI Full Gene Nameleukemia inhibitory factor
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) FGF receptor modulates planar cell polarity in the neuroectoderm via Vangl2 tyrosine phosphorylationNature communicationsAugust 5, 2025Chuykin I, Sokol SY.

(2) IL-27 elicits a cytotoxic CD8(+) T cell program to enforce tumour controlNatureMarch 1, 2025Bréart B, Williams K, Krimm S, Wong T, Kayser BD, Wang L, Cheng E, Cruz Tleugabulova M, Bouziat R, Lu T, et al.

(3) Cooperative role of LSD1 and CHD7 in regulating differentiation of mouse embryonic stem cellsScientific reportsNovember 18, 2024Malla S, Martinez-Gamero C, Kumari K, Achour C, Mermelekas G, Martinez-Delgado D, Coego A, Guallar D, Roman AC, Aguilo F.

(4) Regulation of Sex-biased Gene Expression by the Ancestral X-Y Chromosomal Gene Pair Kdm5c-Kdm5dbioRxiv : the preprint server for biologyOctober 27, 2024Malcore RM, Samanta MK, Kalantry S, Iwase S.

(5) Oncogenic KRAS-Dependent Stromal Interleukin-33 Directs the Pancreatic Microenvironment to Promote Tumor GrowthCancer discoveryOctober 4, 2024Donahue KL, Watkoske HR, Kadiyala P, Du W, Brown K, Scales MK, Elhossiny AM, Espinoza CE, Lasse Opsahl EL, Griffith BD, et al.

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(7) ILC2-derived LIF licences progress from tissue to systemic immunityNatureAugust 1, 2024Gogoi M, Clark PA, Ferreira ACF, Rodriguez Rodriguez N, Heycock M, Ko M, Murphy JE, Chen V, Luan SL, Jolin HE, et al.

(8) EDA2R-NIK signalling promotes muscle atrophy linked to cancer cachexiaNatureMay 1, 2023Bilgic SN, Domaniku A, Toledo B, Agca S, Weber BZC, Arabaci DH, Ozornek Z, Lause P, Thissen JP, Loumaye A, et al.

(9) The myokine Fibcd1 is an endogenous determinant of myofiber size and mitigates cancer-induced myofiber atrophyNature communicationsMay 2, 2022Graca FA, Rai M, Hunt LC, Stephan A, Wang YD, Gordon B, Wang R, Quarato G, Xu B, Fan Y, et al.mouse TNFα, R&D Systems, #410-ML-025) at 100 ng/mL79, and LIF (recombinant mouse LIF, R&D Systems, #8878-lf-025) at 20 ng/mL78. Recombinant Fibcd1 (rFibcd1) was added to serum-free media at 10 ng/mL and 100 ng/mL,

(10) Androgens increase excitatory neurogenic potential in human brain organoidsNatureFebruary 1, 2022Kelava I, Chiaradia I, Pellegrini L, Kalinka AT, Lancaster MA.cultured on Martigel®-coated plates in Stemflex™ medium,with 1μg/mL recombinant mouse LIF (R&D Systems, 8878-LF-025). We used the commercial kit, as in the generation of human organoids, with the following modifications:

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(14) DNER modulates the length, polarity and synaptogenesis of spiral ganglion neurons via the Notch signaling pathwayMolecular medicine reportsFebruary 1, 2018Du J, Wang X, Zhang X, Zhang X, Jiang H.

(15) Data-Modeling Identifies Conflicting Signaling Axes Governing Myoblast Proliferation and Differentiation Responses to Diverse Ligand StimuliCellular and molecular bioengineeringOctober 1, 2017Loiben AM, Soueid-Baumgarten S, Kopyto RF, Bhattacharya D, Kim JC, Cosgrove BD.(R&D Systems, #406ML-005), 10 ng mL1 OSM (R&D Systems, #495MO-025), 10 ng mL1 LIF (R&D Systems, #8878-LF025); 10 ng mL1 TNF-a (R&D Systems, #410-MT010), 10 ng mL1 IL-1a (R&D Systems, #400-ML005). Each of the

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(17) Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland TumorsCancer researchApril 15, 2017Valenti G, Quinn HM, Heynen GJJE, Lan L, Holland JD, Vogel R, Wulf-Goldenberg A, Birchmeier W.

(18) Morphological, molecular and FTIR spectroscopic analysis during the differentiation of kidney cells from pluripotent stem cellsBiological researchApril 4, 2017Mata-Miranda MM, Vazquez-Zapien GJ, Rojas-Lopez M, Sanchez-Monroy V, Perez-Ishiwara DG, Delgado-Macuil RJ.

(19) miR-124 promotes the neuronal differentiation of mouse inner ear neural stem cellsInternational journal of molecular medicineNovember 1, 2016Jiang D, Du J, Zhang X, Zhou W, Zong L, Dong C, Chen K, Chen Y, Chen X, Jiang H.

(20) Induction of LIFR confers a dormancy phenotype in breast cancer cells disseminated to the bone marrowNature cell biologyOctober 1, 2016Johnson RW, Finger EC, Olcina MM, Vilalta M, Aguilera T, Miao Y, Merkel AR, Johnson JR, Sterling JA, Wu JY, et al.

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LIF Protein

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LIF Protein

Recombinant Mouse LIF Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse LIF Protein from R&D Systems, a Bio-Techne Brand

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