Fig 1: Histopathologic and expression profile changes in the CC tissues. (A) Real-time polymerase chain reaction (PCR) analysis of biomarker candidates in human tissues. *P<0.05 vs. control group, **P<0.01 vs. control group, and ***P<0.001 vs. control group. (B) Representative Western blot analysis of ALDOB protein expression in human tissues. (C,D) Representative image of Hematoxylin and Eosin and immunohistochemical staining of ALDOB in human tissues. Bar =100 µm. CC, choledochal cyst; IGFBP2, insulin-like growth factor binding protein 2; TPM3, tropomyosin; ALDOB, fructose-bisphosphate aldolase B; FAH, fumarylacetoacetate hydrolase; SOD3, superoxide dismutase 3; SPARC, secreted protein acidic and cysteine rich; APOE, apolipoprotein E; RBP4, retinol binding protein 4.