Recombinant Human TGF-beta 3 (CHO-expressed) Protein 8420-B3-005 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human TGF-beta 3 (CHO-expressed) Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $260.00Supplier Page View Company Product Page
Catalog Number8420-B3-005
Size5 ug (also 25 ug)
SpeciesHuman
Molecule NameTGF-beta 3
Source/Expression SystemCHO-derived Recombinant Human TGF-beta 3 (CHO-expressed) Protein
NCBI Full Gene Nametransforming growth factor beta 3
NCBI Gene AliasesLDS5, TGF-beta3, RNHF, ARVD1, ARVD
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 9-11 kDa, reducing conditions
Theoretical: 13 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Alternative pre-mRNA Splicing and Gene Expression Patterns in Midbrain Lineage Cells Carrying Familial Parkinson’s Disease MutationsbioRxivSeptember 11, 2025Yeon J. Lee, Khaja Syed, Oriol Busquets, Hanqin Li, Jesse Dunnack, Helen S. Bateup, Frank Soldner, Dirk Hockemeyer, Donald C. Rioascorbic acid (AA) (Sigma, A40–34) 500 μM dbcAMP (SelleckChem, S7858) and 1 ng/ml TGFb3 (R&D Systems, 8420-B3-005). On Day 11, cells were dissociated with Accutase (ThermoFisher, 00-4555-56) and split into a 1:2 or

(2) Hepatic stellate cells control liver zonation, size and functions via R-spondin 3NatureMarch 12, 2025Atsushi Sugimoto, Yoshinobu Saito, Guanxiong Wang, Qiuyan Sun, Chuan Yin, Ki Hong Lee, Yana Geng, Presha Rajbhandari, Celine Hernandez, Marcella Steffani, et al.R&D systems, 240B), TGFβ2 (2.5 ng ml−1, R&D systems, 302-B2-002), TGFβ3 (2.5 ng ml−1, R&D systems, 8420-B3-005), PDGF-BB (20 ng ml−1, R&D systems, 220BB) or IL-1β (5 ng ml−1 R&D systems, 401ML) for evaluation by

(3) Comparison of the chondrogenic potential of eBMSCs and eUCMSCs in response to selected peptides and compoundsBMC veterinary researchFebruary 17, 2025Ajeeb B, Kiyotake EA, Keefe PA, Phillips JN, Hatzel JN, Goodrich LR, Detamore MS.Sigma-Aldrich) was included in the negative control medium. For the positive control, TGF-β3 10 ng/mL (cat# 8420-B3-005, R&D Systems, Minneapolis, MN) was added to the negative control medium. For the experiment evaluating

(4) PI16(+) reticular cells in human palatine tonsils govern T cell activity in distinct subepithelial nichesNature immunologyJuly 1, 2023De Martin A, Stanossek Y, Lütge M, Cadosch N, Onder L, Cheng HW, Brandstadter JD, Maillard I, Stoeckli SJ, Pikor NB, et al.

(5) Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanismsiScienceOctober 21, 2022Ideno H, Imaizumi K, Shimada H, Sanosaka T, Nemoto A, Kohyama J, Okano H.

(6) TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoidsStem cell reportsOctober 11, 2022Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, et al.

(7) TGF-β generates a population of cancer cells residing in G1 phase with high motility and metastatic potential via KRTAP2-3Cell reportsSeptember 27, 2022Takahashi K, Podyma-Inoue KA, Saito M, Sakakitani S, Sugauchi A, Iida K, Iwabuchi S, Koinuma D, Kurioka K, Konishi T, et al.

(8) Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neuronsScientific reportsNovember 15, 2021Earley AM, Burbulla LF, Krainc D, Awatramani R.BDNF (R&D Systems 248-BDB-050/CF), 20 ng/mL GDNF (R&D Systems 212-GD-050), 1 ng/mL TGFB3 (R&D Systems 8420-B3-005), 500 μM cAMP (Enzo Lifescience BML-CN125), 200 μM Ascorbic Acid (AA) (Sigma A5960), and 10 μM DAPT

(9) The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson's diseaseeLifeSeptember 30, 2021de Rus Jacquet A, Tancredi JL, Lemire AL, DeSantis MC, Li WP, O'Shea EK.

(10) Hyaluronic Acid as Macromolecular Crowder in Equine Adipose-Derived Stem Cell CulturesCellsApril 9, 2021Garnica-Galvez S, Korntner SH, Skoufos I, Tzora A, Diakakis N, Prassinos N, Zeugolis DI.

(11) Preparation and Co-Culture of iPSC-Derived Dopaminergic Neurons and AstrocytesCurrent protocols in cell biologyDecember 1, 2019de Rus Jacquet A.

(12) Transforming Growth Factor Beta 3-Loaded Decellularized Equine Tendon Matrix for Orthopedic Tissue EngineeringInternational journal of molecular sciencesNovember 3, 2019Roth SP, Brehm W, Groß C, Scheibe P, Schubert S, Burk J.

(13) Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progressionBreast cancer research : BCRSeptember 18, 2019Ren J, Smid M, Iaria J, Salvatori DCF, van Dam H, Zhu HJ, Martens JWM, Ten Dijke P.

(14) Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect MechanismsCell stem cellMay 2, 2019Wei X, Zhang L, Zhou Z, Kwon OJ, Zhang Y, Nguyen H, Dumpit R, True L, Nelson P, Dong B, et al.

(15) Combined Inhibition of TGF-β Signaling and the PD-L1 Immune Checkpoint Is Differentially Effective in Tumor ModelsCellsApril 5, 2019Sow HS, Ren J, Camps M, Ossendorp F, Ten Dijke P.

(16) Growth Factor-Mediated Tenogenic Induction of Multipotent Mesenchymal Stromal Cells Is Altered by the Microenvironment of Tendon MatrixCell transplantationOctober 1, 2018Roth SP, Schubert S, Scheibe P, Groß C, Brehm W, Burk J.

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TGF-beta 3 Protein

TGF-beta 3 Protein

TGF-beta 3 Protein

Recombinant Human TGF-beta 3 (CHO-expressed) Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human TGF-beta 3 (CHO-expressed) Protein from R&D Systems, a Bio-Techne Brand

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