IFN-beta Protein 8234-MB-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIFN-beta Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $324.00Supplier Page View Company Product Page
Catalog Number8234-MB-010
Size10 ug
SpeciesMouse
Molecule NameIFN-beta
Source/Expression SystemHEK293-derived Recombinant Mouse IFN-beta Protein
NCBI Full Gene Nameinterferon beta 1, interferon beta 1, fibroblast
NCBI Gene AliasesIFB, IFN-beta, IFNB, IFF, Ifb, If1da1
FormatLyophilized from a 0.2 µm filtered solution in PBS and Tween® 80 with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 10 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Double stranded RNA sensing is silenced during early embryonic developmentNat CommunDecember 11, 2025Jeroen Witteveldt, Zicong Liu, Ana Ariza-Cosano, Christian Ramirez, Jessica L. Walters, Pilar G. Marchante, Lars Maas, Elias T. Friman, Alasdair Ivens, Toma Tebaldi, et al.collected and seeded in 24 well plates and incubated with 10 or 100 pg/ml of mouse IFN-β (Bio-techne, 8234-MB-010) for 4 h before collecting the cells in Tri-reagent. Ruxolitinib (Invivogen, tlrl-rux-3) treatment was

(2) Dual nature of type I interferon responses and feedback regulations by SOCS1 dictate malaria mortalityJournal of advanced researchJuly 1, 2025Lu J, Hu Z, Jiang H, Wen Z, Li H, Li J, Zeng K, Xie Y, Chen H, Su XZ, et al.

(3) Analysis of transition metal content in glioblastoma reveals association between iron and survivalTranslational oncologyMay 1, 2025Shenoy G, Sahu A, Kuhn M, Khristov V, Heebner M, Wilding H, Clegg T, Bhanja D, Wade Q, Liermann LJ, et al.washed with fresh media and treated with 100 ng/mL murine recombinant IFN-β (R&D Systems, Catalog #: 8234-MB-010) with or without the addition of glioblastoma-conditioned media. After 24 h of treatment, the media

(4) KLF2 maintains lineage fidelity and suppresses CD8 T cell exhaustion during acute LCMV infectionScienceFebruary 14, 2025Eric Fagerberg, John Attanasio, Christine Dien, Jaiveer Singh, Emily A. Kessler, Leena Abdullah, Jian Shen, Brian G. Hunt, Kelli A. Connolly, Edward De Brouwer, et al.IL-2 (PeproTech, Z 200-02), IL-12 (R&D Systems, 419-ML-010), IL-15 (PeproTech, 210-15), IFNβ (R&D Systems, 8234-MB-010), IL-12 (R&D Systems, 419-ML), or TGFβ (R&D Systems, 7666-MB-005) for 48 hours. For chronic stimulation,

(5) 5′ terminal nucleotide determines the immunogenicity of IVT RNAsNucleic Acids ResearchJanuary 24, 2025Magdalena Wolczyk, Jacek Szymanski, Ivan Trus, Zara Naz, Tola Tame, Agnieszka Bolembach, Nila Roy Choudhury, Karolina Kasztelan, Juri Rappsilber, Andrzej Dziembowski, et al.in parallel by serial dilutions of recombinant IFN-β standard in DMEM (R&D Systems #8499-IF-010 and #8234-MB-010). After overnight incubation (24 h), 20 μl of supernatants were mixed with 180 μl of the working solution

(6) TNF-α exacerbates SARS-CoV-2 infection by stimulating CXCL1 production from macrophagesPLoS pathogensDecember 1, 2024Kobayashi M, Kobayashi N, Deguchi K, Omori S, Nagai M, Fukui R, Song I, Fukuda S, Miyake K, Ichinohe T.recombinant mouse IFN-α (Cat#HC1040-10) was purchased from Hycult Biotech. A recombinant mouse IFN-β (Cat#8234-MB-010) was obtained from R&D Systems. Recombinant mouse CXCL1 (Cat#250–11) and TNF-α (Cat#315-01A) were from

(7) VSV(∆M51) drives CD8(+) T cell-mediated tumour regression through infection of both cancer and non-cancer cellsNature communicationsNovember 15, 2024Rajwani J, Vishnevskiy D, Turk M, Naumenko V, Gafuik C, Kim DS, Mah LK, Snelling S, Gonzales GA, Xue J, et al.

(8) Apobec-mediated retroviral hypermutation in vivo is dependent on mouse strainPLOS PathogensAugust 29, 2024Hyewon Byun, Gurvani B. Singh, Wendy Kaichun Xu, Poulami Das, Alejandro Reyes, Anna Battenhouse, Dennis C. Wylie, Mario L. Santiago, Mary M. Lozano, Jaquelin P. Dudley100mm Petri dishes containing 15 ml of complete RPMI media plus 200 to 1000 U/ml IFN-β (R&D Systems 8234MB010). All cells were grown in a 37°C incubator with 7.5% CO2 for 4 h to 4 days (as indicated) prior to cell

(9) TBK1 and IKKε protect target cells from IFNγ-mediated T cell killing via an inflammatory apoptotic mechanismbioRxiv : the preprint server for biologyAugust 8, 2024Sun ND, Carr AR, Krogman EN, Chawla Y, Zhong J, Guttormson MC, Chan M, Hsu MA, Dong H, Bogunovic D, et al.were from the following sources: TNF (PeproTech, 315–01A), IFNγ (PeproTech, 315–05), IFNβ (Bio-Techne, 8234-MB-010), Necrostatin-1s (MedChemExpress, HY-14622A), Ruxolitinib (MedChemExpress, 50–202-9341) LCMV GP33 (GenScript,

(10) Tumoral Interferon Beta Induces an Immune-Stimulatory Phenotype in Tumor-Associated Macrophages in Melanoma Brain MetastasesCancer Research CommunicationsAugust 1, 2024Julia Gellert, Dennis A. Agardy, Swaminathan Kumar, Alexandros Kourtesakis, Tamara Boschert, Kristine Jähne, Michael O. Breckwoldt, Lukas Bunse, Wolfgang Wick, Michael A. Davies, et al.After 48 hours, BMDM were treated with BMDM medium supplemented with recombinant IFNβ (Bio-Techne Cat# 8234-MB-010), tumor cell culture supernatant with tumoral IFNβ, tumor cell culture supernatant or unsupplemented

(11) Tumoral Interferon Beta Induces an Immune-Stimulatory Phenotype in Tumor-Associated Macrophages in Melanoma Brain MetastasesCancer Res CommunAugust 1, 2024Julia Gellert, Dennis A. Agardy, Swaminathan Kumar, Alexandros Kourtesakis, Tamara Boschert, Kristine Jähne, Michael O. Breckwoldt, Lukas Bunse, Wolfgang Wick, Michael A. Davies, et al.After 48 hours, BMDM were treated with BMDM medium supplemented with recombinant IFNβ (Bio-Techne Cat# 8234-MB-010), tumor cell culture supernatant with tumoral IFNβ, tumor cell culture supernatant or unsupplemented

(12) Type-I-interferon-responsive microglia shape cortical development and behaviorCellApril 11, 2024Escoubas CC, Dorman LC, Nguyen PT, Lagares-Linares C, Nakajo H, Anderson SR, Barron JJ, Wade SD, Cuevas B, Vainchtein ID, et al.oligodendrocytes, and microglia. Interferon β injection A solution of 10ng interferon-β (IFN-β, R&D Systems, 8234-MB-010) diluted in PBS (2μl) was slowly delivered by intracerebroventricular injection into hypothermia-anesthetized

(13) SOXC are critical regulators of adult bone massNature communicationsApril 5, 2024Angelozzi M, Karvande A, Lefebvre V.Thermo Fisher Scientific) according to the manufacturer’s instructions. After 8 h, cells were treated with mouse IFN-β (8234MB010, R&D Systems) at indicated doses. They were analyzed 20 h later. Quantitative reverse transcription

(14) Salmonella Typhimurium infection inhibits macrophage IFNβ signaling in a TLR4-dependent mannerbioRxiv : the preprint server for biologyMarch 5, 2024Shuster M, Lyu Z, Augenstreich J, Mathur S, Ganesh A, Ling J, Briken V.

(15) The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironmentNature communicationsFebruary 24, 2024Hardaker EL, Sanseviero E, Karmokar A, Taylor D, Milo M, Michaloglou C, Hughes A, Mai M, King M, Solanki A, et al.

(16) Lymph node and tumor-associated PD-L1(+) macrophages antagonize dendritic cell vaccines by suppressing CD8(+) T cellsCell reports. MedicineJanuary 16, 2024Sprooten J, Vanmeerbeek I, Datsi A, Govaerts J, Naulaerts S, Laureano RS, Borràs DM, Calvet A, Malviya V, Kuballa M, et al.proteins" ,, Recombinant Murine TNF,Miltenyi Biotec,Cat#130-101-687 Recombinant Murine IFNβ,R&D systems,Cat#8234-MB-010 Recombinant Murine IL4,Peprotech,Cat#214-14 Recombinant Murine M-CSF,Peprotech,Cat#315-02 Recombinant Murine GM-CSF

(17) Cullin5 drives experimental asthma exacerbations by modulating alveolar macrophage antiviral immunityNature communicationsJanuary 4, 2024Zhang H, Xue K, Li W, Yang X, Gou Y, Su X, Qian F, Sun L.

(18) Apobec-Mediated Retroviral Hypermutation In Vivo is Dependent on Mouse StrainbioRxiv : the preprint server for biologyNovember 2, 2023Byun H, Singh GB, Xu WK, Das P, Reyes A, Battenhouse A, Wylie DC, Lozano MM, Dudley JP.

(19) Approaches for timeline reductions in pathogenesis studies using genetically modified miceMicrobiology SpectrumOctober 17, 2023Samantha Skavicus, Nicholas S. Heatonand qRT-PCR Mouse fibroblasts were incubated with 500 U/mL mouse IFN-β protein (R&D Systems, Cat. # 8234 MB-010) in fibroblast media for 6 h at 37°C with 5% CO2. After incubation, mouse IFN-β was removed and Monarch

(20) Systematic identification of gene combinations to target in innate immune cells to enhance T cell activationNature communicationsOctober 9, 2023Xia L, Komissarova A, Jacover A, Shovman Y, Arcila-Barrera S, Tornovsky-Babeay S, Jaya Prakashan MM, Nasereddin A, Plaschkes I, Nevo Y, et al.

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Recombinant Mouse IFN-beta Protein

IFN-beta Protein

IFN-beta Protein

IFN-beta Protein

IFN-beta Protein

IFN-beta Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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IFN-beta Protein from R&D Systems, a Bio-Techne Brand

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