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Cell Biology
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Z-AAD-CMK
Z-AAD-CMK from Enzo Life Sciences, Inc.
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Citations:
(2)
Supplier Page
Supplier Page from
Enzo Life Sciences, Inc. for
Z-AAD-CMK
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Description
Irreversible, cell-permeable inhibitor of granzyme B (ID50=0.3 µM). Does not inhibit granzyme A. Inhibition of granzyme B with Z-AAD-CMK prevented caspase-3 activation in T cells
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Z-AAD-CMK
Company
Enzo Life Sciences, Inc.
Price
$141.00
Supplier Page
View Company Product Page
Catalog Number
BML-P165-0001
Size
1 mg
Format
Lyophilized
Purity
≥95% (HPLC)
Molecular Weight
441.9
Molecule Name
Z-AAD-CMK
Source/Expression System
Synthetic
Formula
C
19
H
24
ClN
3
O
7
Type
Peptide
Specifications/Features
Caspase inhibitor
Sequence
Benzyloxycarbonyl-Ala-Ala-Asp-chloromethylketone
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Enzo Life Sciences, Inc.
10 Executive Blvd.
Farmingdale
,
NY
11735
United States
Phone
: 800-942-0430
Fax: 610-941-9252
Company Profile
Website:
www.enzo.com
Citations (2)
(1)
Th9 Cells Represent a Unique Subset of CD4
+
T Cells Endowed with the Ability to Eradicate Advanced Tumors
Cancer cell
June 11, 2018
Lu Y, Wang Q, Xue G, Bi E, Ma X, Wang A, Qian J, Dong C, Yi Q.
QNZ
,
Santa Cruz Biotechnology
,
sc-200675
Granzyme B specific
inhibitor
Z-AAD-CMK
,
Enzo Life Sciences
,
BML-P165-0001
"
3,4 Dichloroisocoumarin
(DCI), inhibits granzymesA, B, and H",
Santa Cruz Biotechnology
.,
sc-3502
MHC
(2)
Folate receptor 1 (FOLR1) targeted chimeric antigen receptor (CAR) T cells for the treatment of gastric cancer
PloS one
January 1, 2018
Kim M, Pyo S, Kang CH, Lee CO, Lee HK, Choi SU, Park CH.
EnVision reader (PerkinElmer, USA). To investigate the cytotoxicity pathway, 100 μM of
Z-AAD-CMK
(Cat. #
BML-P165-0001
,
Enzo Life Sciences
, USA) or 0.1 μg/ml of neutralization antibodies, anti-hFas ligand (Cat. #
MAB126
,
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Z-AAD-CMK from Enzo Life Sciences, Inc.
Supplier Page
View Company Product Page
$141.00
Product Specs
Company Info
Citations
Reviews
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