Recombinant Human TGF-beta 1 (Human Cell-expressed) Protein 7754-BH-005 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human TGF-beta 1 (Human Cell-expressed) Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $306.00Supplier Page View Company Product Page
Catalog Number7754-BH-005
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 11 kDa, reducing conditions
Theoretical: 12.8 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Gene AliasesTGF-beta1, TGFB, DPD1, TGFbeta, CED, IBDIMDE, LAP
NCBI Full Gene Nametransforming growth factor beta 1
Source/Expression SystemHEK293-derived Recombinant Human TGF-beta 1 (Human Cell-expressed) Protein
SpeciesHuman
Molecule NameTGF-beta 1
Size5 ug (also 25 ug, 100 ug, 500 ug, 1000 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal MetastasisCancer ResApril 16, 2026Amal T. Elhaw, Priscilla W. Tang, Ya-Yun Cheng, Shriya Kamlapurkar, Zaineb Javed, Sarah Al-Saad, Sierra R. White, Ahmed Emam Abdelnaby, Hannah Khan, Alex Seok Choi, et al.hrs of serum starvation, cells were stimulated with 10 ng/mL recombinant human TGF-β1 (R&D Systems, 7754-BH-005) for 0, 15, 30, 60, or 120 minutes. At each time point, cells were lysed and processed for protein extraction

(2) Particulate matter increases bone morphogenetic protein 2 in lung fibroblastsAmerican Journal of Physiology-Lung Cellular and Molecular PhysiologyJanuary 1, 2026Nathan Craig, Jack P. Berens, Eistine Boateng, Anne M. Scruggs, Julia J. Khater, Yahong Chen, Furong Deng, Steven K. HuangFor assessment in established myofibroblasts, cells were treated first with 2 ng/ml of TGF-β1 (cat # 7754-BH-005; R&D Systems) for 48 h before being washed and subsequently exposed to exogenous BMP2. In some experiments,

(3) EMT-induced stem cell and mesenchymal programs can be decoupled via cell division and ESRP1-dependent mechanismsiScienceDecember 1, 2025Petra den Hollander, Maria Castaneda, Suhas V. Vasaikar, Joanna Joyce Maddela, Claire Gould, Breanna R. Demestichas, Robiya Joseph, Shivangi Agarwal, Abhijeet P. Deshmukh, Alvina Zia, et al.recombinant proteins","Chemicals, peptides, and recombinant proteins" ,, TGF-β1,Novus Biologicals,7754-BH-005 Thymidine,Sigma,T1895 Lovastatin,Sigma,438185 Mevalonolactone,Sigma,M4667 4-hydroxytamoxifen,Sigma,T176-10MG ,, Critical

(4) Reconstructing EBV reactivation and DNA damage response kinetics in morphologic pseudotimebioRxivOctober 8, 2025Dina G. Tekle, Jonathan Z. Sexton, Elliott D. SoRelletreated with lytic inducing agents at the following concentrations: 5 ng/mL TGF-beta (R&D Systems, 7754-BH-005), 10 μg/mL goat anti-human IgG (Jackson ImmunoResearch, 109–005-170), 25 nM TPA (Phorbol-12-myristate-13-acetate)

(5) MKLN1-dependent GID4/CTLH E3 ubiquitin ligase complex assemblies are required to support B-cell antibody diversificationThe Journal of ImmunologyOctober 1, 2025Philip Barbulescu, Matthew K Wong, Leon Baronian, Pengyu Wang, Abdulmateen Aderinto, Matthias Kneussel, Alberto MartinIgA (10 ng/μL IL-4; 10 ng/μL Anti-IgD dextran; 5 ng/μL IL-5, BD, 554581; 1 ng/μL TGFb, R&D Systems, 7754-BH-005). Cells were harvested 4 d poststimulation and stained with fixable viability dye (FVD) eFluor780 (Thermo

(6) TGFβ1–TNFα-regulated secretion of neutrophil chemokines is independent of epithelial–mesenchymal transition in breast tumor cellsMolecular Biology of the CellOctober 1, 2025Shuvasree SenGupta, Erez Cohen, Joseph Serrenho, Kaleb Ott, Pierre A. Coulombe, Carole A. Parentto promote cancer cell aggressiveness. MATERIALS AND METHODS Materials TGF-β1 from R&D Systems (7754-BH-005) or Peprotech (100-21); TNF-α from Peprotech (300-01A) or Prospec (cyt-114); human recombinant CXCL8

(7) Overcoming Immune Checkpoint Inhibitor Resistance with Potent, Selective Dual αvβ6/8 Inhibitors Based on Engineered Lasso PeptidesJournal of the American Chemical SocietySeptember 10, 2025Lechner A, Jordan PA, Machado da Cruz GC, Lamson J, Gordon J, Okada BK, Anderson K, Chaudhari R, Rosario CJ, Mikesell J, et al.

(8) Mouse trophectoderm stem cells generated with morula signalling inducers capture an early trophectoderm stateNature cell biologySeptember 1, 2025Gao Y, Li M, Guan W, Guo W, Wei S, Yan F, Han W, Zhang X, Yin T, Dang Y, et al.

(9) BRD4 Mediates Transforming Growth Factor-β-Induced Smooth Muscle Cell Differentiation from Mesenchymal Progenitor CellsInternational journal of molecular sciencesAugust 21, 2025Olajuyin A, Mandlem V, Sunil C, Hou Y, Adeyanju O, Petkar S, Li Q, Tucker TA, Idell S, Chen SY, et al.

(10) Spatial Biology and Organoid Technologies Reveal a Potential Therapy-Resistant Cancer Stem Cell Population in Pancreatic Ductal AdenocarcinomabioRxiv : the preprint server for biologyMay 24, 2025Adhikary P, Chakrabarti J, Wang J, Ezuma-Igwe U, Sun X, Bastian WC, Braissand N, Corbett MP, Douglass E, Kim S, et al.

(11) Histological signatures map anti-fibrotic factors in mouse and human lungsNatureMay 22, 2025Jason L. Guo, Michelle Griffin, Jung-Ki Yoon, David M. Lopez, Yili Zhu, John M. Lu, Georgios Mikos, Jennifer B. L. Parker, Shamik Mascharak, Camille Brenac, et al.of standard PCLS media or a fibrosis cocktail (FC) of PCLS media33 with 5 ng ml−1 TGFβ (R&D Systems, 7754-BH-005), 10 ng ml−1 PDGF-AB (BioLegend, 788604), 10 ng ml−1 TNF (R&D Systems, 410-MT-010) and 5 μM lysophosphatidic

(12) Characterization of a pathogenic nonmigratory fibroblast population in systemic sclerosis skinJCI insightMay 22, 2025Clark KE, Xu S, Attar M, Ong VH, Buckley CD, Denton CP.

(13) Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4(+) T cells through STAT1-related epigenetic mechanismseLifeMay 14, 2025Zhang J, Tang H, Wu H, Pang X, Jin R, Zhang Y.

(14) Proteome Alterations in Cardiac Fibroblasts: Insights from Experimental Myocardial Infarction and Clinical Ischaemic CardiomyopathyInt J Mol SciApril 18, 2025Adam Russell-Hallinan, Claire Tonry, Lauren Kerrigan, Kevin Edgar, Patrick Collier, Ken McDonald, Mark Ledwidge, David Grieve, Narainrit Karuna, Chris Watsonfibroblasts in serum-free media were treated with TGF-β (5 µg/mL (R&D Systems, Minneapolis, MN, USA, 7754-BH-005/C)) for 24 h. Cell pellets were collected and stored at 80 °C until further analysis. 4.5. Sample Preparation

(15) Transcriptional signature of rapidly responding NK cells reveals S1P5 and CXCR4 as anti-tumor response disruptorsScientific reportsMarch 28, 2025Puig-Gámez M, Van Attekum M, Theis T, Dick A, Park JE.

(16) TNBC response to paclitaxel phenocopies interferon response which reveals cell cycle-associated resistance mechanismsSci RepFebruary 4, 2025Nicholas L. Calistri, Tiera A. Liby, Zhi Hu, Hongmei Zhang, Mark A. Dane, Sean M. Gross, Laura M. Heisergamma,IFNG,20 ng/mL,R&D systems,385-IR-100,0.1% PBS Transforming growth factor beta,TGFB,10 ng/mL,Biotechne,7754BH005,0.1% PBS Lymphotoxin,LT,10 ng/mL,Biotechne,8884-LY-025,0.1% PBS Oncostatin M,OSM,10 ng/mL,Cell signaling technology

(17) Alleviation of liver fibrosis by inhibiting a non-canonical ATF4-regulated enhancer program in hepatic stellate cellsNat CommunJanuary 9, 2025Li-Xian Yang, Chuangye Qi, Si Lu, Xiang-Shi Ye, Parnaz Merikhian, Du-Yu Zhang, Tao Yao, Jiang-Sha Zhao, Ying Wu, Yongshi Jia, et al.concentration of 40 ng/ml. Phosphorated eIF2α inhibitor ISRIB (B3699) was purchased from APExBIO. TGFβ (7754-BH-005) was obtained from R&D Systems. CCl4 (C805329) was purchased from MACKUN. PDGF-BB (220-BB) was purchased

(18) Unsupervised inter-domain transformation for virtually stained high-resolution mid-infrared photoacoustic microscopy using explainable deep learningNature communicationsDecember 30, 2024Park E, Misra S, Hwang DG, Yoon C, Ahn J, Kim D, Jang J, Kim C.

(19) TGFβ signaling sensitizes MEKi-resistant human melanoma to targeted therapy-induced apoptosisCell death & diseaseDecember 21, 2024Loos B, Salas-Bastos A, Nordin A, Debbache J, Stierli S, Cheng PF, Rufli S, Wyss C, Levesque MP, Dummer R, et al.

(20) Tissue-specific functions of MSCs are linked to homeostatic muscle maintenance and alter with agingAging cellNovember 1, 2024Kurosawa T, Ikemoto-Uezumi M, Yoshimoto Y, Minato K, Kaji N, Chaen T, Hase E, Minamikawa T, Yasui T, Horiguchi K, et al.

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TGF-beta 1 Protein

TGF-beta 1 Protein

TGF-beta 1 Protein

Recombinant Human TGF-beta 1 (Human Cell-expressed) Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human TGF-beta 1 (Human Cell-expressed) Protein from R&D Systems, a Bio-Techne Brand

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