IL-17/IL-17A Protein 7955-IL-025/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-17/IL-17A Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $328.00Supplier Page View Company Product Page
Catalog Number7955-IL-025/CF
Size25 ug (also 10 ug, 100 ug)
Molecule NameIL-17/IL-17A
SpeciesHuman
Source/Expression SystemHEK293-derived Recombinant Human IL-17A (Human Cell-expressed) Protein, CF
NCBI Full Gene Nameinterleukin 17A
NCBI Gene AliasesIL-17A, ILA17, CTLA-8, CTLA8, IL17, IL-17
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 25 ug (also 10 ug, 100 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) In vivo detection of immune responses via cytokine activity labelingCellFebruary 5, 2026Guangqing Lu, Shanshan Zhang, Mengyang Feng, Eunha Kim, Daniel Cho, Jae Hyun Kim, Hannah Caris, Lev Silberstein, Gloria B. Choi, Jun R. HuhRecombinant Mouse TNF-α (carrier-free),BioLegend,Cat# 575202 "Recombinant Human IL-17A (Human Cell-expressed) Protein, CF",R&D Systems,Cat# 7955-IL-025/CF RPMI 1640 media,VWR,Cat# 45000–404 StartingBlock™ T20 (TBS) Blocking Buffer,Thermo Fisher Scientific,Cat#

(2) LIGHT in combination with IL-13 or IL-17 drives inflammatory transcriptional signatures in human pulmonary fibroblasts relevant for human lung diseaseImmunoHorizonsSeptember 17, 2025Nandita Ghosh, Rinkesh Kumar Gupta, Jeamin Jung, Kai Fung, Michael Croftcytokines were purchased from R&D Systems: rLIGHT (664-LI-025/CF), r1L-13 (213-ILB-010), and rIL-17A (7955-IL-025/CF). HPF cell culture Healthy HPF cells were obtained from ScienCell (Cat. #3300, lot #27039). A single

(3) Interferon-gamma is quintessential for NOS2 and COX2 expression in ER(-) breast tumors that lead to poor outcomeCell death & diseaseMay 11, 2023Cheng RYS, Ridnour LA, Wink AL, Gonzalez AL, Femino EL, Rittscher H, Somasundaram V, Heinz WF, Coutinho L, Rangel MC, et al.

(4) Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel diseaseCell reportsSeptember 27, 2022Pavlidis P, Tsakmaki A, Treveil A, Li K, Cozzetto D, Yang F, Niazi U, Hayee BH, Saqi M, Friedman J, et al.

(5) Evidence for anti-inflammatory effects and modulation of neurotransmitter metabolism by Salvia officinalis LBMC complementary medicine and therapiesMay 12, 2022Margetts G, Kleidonas S, Zaibi NS, Zaibi MS, Edwards KD.

(6) IL-17A Damages the Blood-Retinal Barrier through Activating the Janus Kinase 1 PathwayBiomedicinesJuly 16, 2021Byrne EM, Llorián-Salvador M, Tang M, Margariti A, Chen M, Xu H.

(7) Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophreniaNature neuroscienceNovember 1, 2020Park GH, Noh H, Shao Z, Ni P, Qin Y, Liu D, Beaudreault CP, Park JS, Abani CP, Park JM, et al.inflammatory cytokine expression. For IL17 treatment, 100ng/ml human recombinant IL17 protein (Cat# 7955-IL-025/CF, R&D systems) was added to cIN culture for 24hours and cells were harvested for RNA preparation. The

(8) IL-10 Dampens an IL-17-Mediated Periodontitis-Associated Inflammatory NetworkJournal of immunology (Baltimore, Md. : 1950)April 15, 2020Sun L, Girnary M, Wang L, Jiao Y, Zeng E, Mercer K, Zhang J, Marchesan JT, Yu N, Moss K, et al.supplemented medium. Cells were either treated with recombinant human IL-17(A) cytokine (catalog no. 7955-IL-025/CF; R&D Systems, Minneapolis, MN) at a final concentration of 100 ng/ml in the presence or absence of 10

(9) Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative studyBMC rheumatologyJanuary 1, 2020Sinkeviciute D, Aspberg A, He Y, Bay-Jensen AC, Önnerfjord P.

(10) IL-36γ regulates mediators of tissue homeostasis in epithelial cellsCytokineJuly 1, 2019Heath JE, Scholz GM, Veith PD, Reynolds EC.

(11) Gamma Interferon and Interleukin-17A Differentially Influence the Response of Human Macrophages and Neutrophils to Pseudomonas aeruginosa InfectionInfection and immunityFebruary 1, 2019Muntaka S, Almuhanna Y, Jackson D, Singh S, Afryie-Asante A, Cámara M, Martínez-Pomares L.rhIFN-␥ [10 ng/ml] [catalog no. 285-IF-100; R&D Systems, Inc.] or rhIL-17A/CF [15 ng/ml] [catalog no. 7955-IL-025/CF; R&D Systems, Inc.]) in the presence of GM-CSF on day 6, and macrophage-neutrophil cocultures were incubated

(12) Intramuscular vaccination of guinea pigs with the live-attenuated human herpes simplex vaccine VC2 stimulates a transcriptional profile of vaginal Th17 and regulatory Tr1 responsesVaccineMay 11, 2018Stanfield BA, Rider PJF, Caskey J, Del Piero F, Kousoulas KG.

(13) Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axisNatureApril 1, 2018Bambouskova M, Gorvel L, Lampropoulou V, Sergushichev A, Loginicheva E, Johnson K, Korenfeld D, Mathyer ME, Kim H, Huang LH, et al.

(14) Population snapshots predict early haematopoietic and erythroid hierarchiesNatureMarch 1, 2018Tusi BK, Wolock SL, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, Waisman A, Huh JR, Klein AM, Socolovsky M.

(15) RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene SignatureFrontiers in immunologyJanuary 1, 2018Swindell WR, Beamer MA, Sarkar MK, Loftus S, Fullmer J, Xing X, Ward NL, Tsoi LC, Kahlenberg MJ, Liang Y, et al.

(16) Prolonging culture of primary human keratinocytes isolated from suction blisters with the Rho kinase inhibitor Y-27632PloS oneJanuary 1, 2018Anderson ED, Sastalla I, Earland NJ, Mahnaz M, Moore IN, Otaizo-Carrasquero F, Myers TG, Myles CA, Datta SK, Myles IA.

(17) The small molecule rhodomyrtone suppresses TNF-α and IL-17A-induced keratinocyte inflammatory responses: A potential new therapeutic for psoriasisPloS oneJanuary 1, 2018Chorachoo J, Lambert S, Furnholm T, Roberts L, Reingold L, Auepemkiate S, Voravuthikunchai SP, Johnston A.

(18) Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17PloS oneJanuary 1, 2016Yuki T, Tobiishi M, Kusaka-Kikushima A, Ota Y, Tokura Y.

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IL-17/IL-17A Protein

IL-17/IL-17A Protein

IL-17/IL-17A Protein

IL-17/IL-17A Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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IL-17/IL-17A Protein from R&D Systems, a Bio-Techne Brand

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