Recombinant Human IL-17A (Human Cell-expressed) Protein 7955-IL-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human IL-17A (Human Cell-expressed) Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $328.00Supplier Page View Company Product Page
Catalog Number7955-IL-025
Size25 ug (also 50 ug, 200 ug, 1 mg)
Molecule NameIL-17/IL-17A
SpeciesHuman
Source/Expression SystemHEK293-derived Recombinant Human IL-17A (Human Cell-expressed) Protein
NCBI Full Gene Nameinterleukin 17A
NCBI Gene AliasesIL-17A, ILA17, CTLA-8, CTLA8, IL17, IL-17
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 15-23 kDa, reducing conditions 28-38 kDa, non-reducing conditions
Theoretical: 15.1 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Interleukin-17A facilitates tumor progression via upregulating programmed death ligand-1 expression in hepatocellular carcinomaWorld journal of gastrointestinal oncologyJanuary 15, 2025Yang ZX, Zhang LT, Liu XJ, Peng XB, Mao XR.were cultured at 37 °C with 5% carbon dioxide in a humidified incubator. Recombinant human IL-17A (No. 7955-IL-025) was obtained from R and D Systems. Transforming growth factor (TGF)-beta signal pathway inhibitor (ITD-1)

(2) Alpha-synuclein fine-tunes neuronal response to pro-inflammatory cytokinesBrain, behavior, and immunityNovember 1, 2024Sigutova V, Xiang W, Regensburger M, Winner B, Prots I.

(3) SCF(FBXW11) Complex Targets Interleukin-17 Receptor A for Ubiquitin-Proteasome-Mediated DegradationBiomedicinesMarch 28, 2024Jin B, Moududee SA, Ge D, Zhou P, Wang AR, Liu YZ, You Z.

(4) IκBζ is a dual-use coactivator of NF-κB and POU transcription factorsMolecular cellMarch 21, 2024Alpsoy A, Wu XS, Pal S, Klingbeil O, Kumar P, El Demerdash O, Nalbant B, Vakoc CR.proteins","Chemicals, peptides, and recombinant proteins" TNF-α,R&D Systems,Cat# 210-TA-005 IL-17A,R&D Systems,Cat# 7955-IL-025 "Polyethylenimine, Linear, MW 25,000 (PEI 25000) [for DNA transfection]",Polysciences,Cat# 23966–1 TransIT®-LT1 Transfection Reagent

(5) TNF-α and Poly(I:C) induction of A20 and activation of NF-κB signaling are independent of ABCF1 in human airway epithelial cellsScientific reportsSeptember 7, 2023Cao QT, Ishak M, Shpilman I, Hirota JA.(300-01A, Rocky Hill, New Jersey), Recombinant human IL-17A protein was purchased from R&D Systems (7955-IL-025, Minneapolis, Minnesota); TLR-3 Agonist (tlrl-pic), TLR-4 Agonist (tlrl-b5lps), and TLR-2 Agonist (tlrl-pgns2)

(6) Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel diseaseCell reportsSeptember 27, 2022Pavlidis P, Tsakmaki A, Treveil A, Li K, Cozzetto D, Yang F, Niazi U, Hayee BH, Saqi M, Friedman J, et al.

(7) Evidence for anti-inflammatory effects and modulation of neurotransmitter metabolism by Salvia officinalis LBMC complementary medicine and therapiesMay 12, 2022Margetts G, Kleidonas S, Zaibi NS, Zaibi MS, Edwards KD.(20 μg/ml; batch N0587) in the presence or absence of recombinant human IL-17A protein (R&D Systems, #7955-IL-025) and/or Human IL-17RA/IL-17R Antibody (R&D Systems, #MAB177–100) and incubated for 24 h at 37 °C and

(8) IL-17A reprograms intestinal epithelial cells to facilitate HIV-1 replication and outgrowth in CD4+ T cellsiScienceNovember 19, 2021Wiche Salinas TR, Gosselin A, Raymond Marchand L, Moreira Gabriel E, Tastet O, Goulet JP, Zhang Y, Vlad D, Touil H, Routy JP, et al.Peptides, and Recombinant Proteins" ,, rhIL-2,R&D Systems,Cat#202-IL-050 rhIL-17A,R&D Systems,Cat#7955-IL-025 rhTNF-α,R&D Systems,Cat#210-TA-020 Recombinant Viral B18R Protein,R&D Systems,Cat#8185-BR-025 rhCCL20,R&D Systems

(9) IL-17A Damages the Blood-Retinal Barrier through Activating the Janus Kinase 1 PathwayBiomedicinesJuly 16, 2021Byrne EM, Llorián-Salvador M, Tang M, Margariti A, Chen M, Xu H.

(10) IL-10 Dampens an IL-17-Mediated Periodontitis-Associated Inflammatory NetworkJournal of immunology (Baltimore, Md. : 1950)April 15, 2020Sun L, Girnary M, Wang L, Jiao Y, Zeng E, Mercer K, Zhang J, Marchesan JT, Yu N, Moss K, et al.

(11) Targeting IL-17A/glucocorticoid synergy to CSF3 expression in neutrophilic airway diseasesJCI insightFebruary 13, 2020Ouyang S, Liu C, Xiao J, Chen X, Lui AC, Li X.and cell culture. Mouse TGF-β1 (catalog 7666-MB), mouse IL-6 (catalog 406-ML), human IL-17A (catalog 7955-IL-025), mouse IL-17A (catalog 7956-ML-025), mouse TNF-α (catalog 10-MT), and anti-CSF3 neutralizing antibody

(12) Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative studyBMC rheumatologyJanuary 1, 2020Sinkeviciute D, Aspberg A, He Y, Bay-Jensen AC, Önnerfjord P.

(13) IL-36γ regulates mediators of tissue homeostasis in epithelial cellsCytokineJuly 1, 2019Heath JE, Scholz GM, Veith PD, Reynolds EC.

(14) Gamma Interferon and Interleukin-17A Differentially Influence the Response of Human Macrophages and Neutrophils to Pseudomonas aeruginosa InfectionInfection and immunityFebruary 1, 2019Muntaka S, Almuhanna Y, Jackson D, Singh S, Afryie-Asante A, Cámara M, Martínez-Pomares L.

(15) Intramuscular vaccination of guinea pigs with the live-attenuated human herpes simplex vaccine VC2 stimulates a transcriptional profile of vaginal Th17 and regulatory Tr1 responsesVaccineMay 11, 2018Stanfield BA, Rider PJF, Caskey J, Del Piero F, Kousoulas KG.

(16) Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axisNatureApril 1, 2018Bambouskova M, Gorvel L, Lampropoulou V, Sergushichev A, Loginicheva E, Johnson K, Korenfeld D, Mathyer ME, Kim H, Huang LH, et al.

(17) Population snapshots predict early haematopoietic and erythroid hierarchiesNatureMarch 1, 2018Tusi BK, Wolock SL, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, Waisman A, Huh JR, Klein AM, Socolovsky M.H4230) supplemented with either EPO (0.05U/ml), and in the presence or absence of IL-17a (R&D systems 7955-IL-025). CFUe colonies were scored from triplicate plates on day 7. Cell cycle studies Flow cytometric cell

(18) Prolonging culture of primary human keratinocytes isolated from suction blisters with the Rho kinase inhibitor Y-27632PloS oneJanuary 1, 2018Anderson ED, Sastalla I, Earland NJ, Mahnaz M, Moore IN, Otaizo-Carrasquero F, Myers TG, Myles CA, Datta SK, Myles IA.

(19) The small molecule rhodomyrtone suppresses TNF-α and IL-17A-induced keratinocyte inflammatory responses: A potential new therapeutic for psoriasisPloS oneJanuary 1, 2018Chorachoo J, Lambert S, Furnholm T, Roberts L, Reingold L, Auepemkiate S, Voravuthikunchai SP, Johnston A.

(20) RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene SignatureFrontiers in immunologyJanuary 1, 2018Swindell WR, Beamer MA, Sarkar MK, Loftus S, Fullmer J, Xing X, Ward NL, Tsoi LC, Kahlenberg MJ, Liang Y, et al.

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IL-17/IL-17A Protein

IL-17/IL-17A Protein

IL-17/IL-17A Protein

Recombinant Human IL-17A (Human Cell-expressed) Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human IL-17A (Human Cell-expressed) Protein from R&D Systems, a Bio-Techne Brand

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