Recombinant Mouse TGF-beta 1 Protein 7666-MB-005 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse TGF-beta 1 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $421.00Supplier Page View Company Product Page
Catalog Number7666-MB-005
Size5 ug
Molecule NameTGF-beta 1
SpeciesMouse
Source/Expression SystemCHO-derived Recombinant Mouse TGF-beta 1 Protein
NCBI Full Gene Nametransforming growth factor, beta 1
NCBI Gene AliasesTGF-beta1, Tgfb, TGFbeta1, Tgfb-1
FormatLyophilized from a 0.2 µm filtered solution in HCl with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 10.5 kDa, reducing conditions
Theoretical: 12.8 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Serum Response Factor (SRF) promotes actin cytoskeletal organization in adipocytes to support adaptive hypertrophic expansion and tissue remodeling during obesity in miceMetabolismMay 1, 2026Jisun So, Jamie Wann, Kyungchan Kim, Solaema Taleb, Hyeong-Geug Kim, Manju Kumari, Alexander S. Banks, X. Charlie Dong, Hyun Cheol Rohfor the remainder of the culture period. For TGF-β treatment, recombinant mouse TGF-β1 (R&D Systems, 7666-MB-005) was reconstituted at 50 μg/mL in 4 mM HCl containing 0.1% BSA and added to culture medium at a final

(2) Dendritic Cell-Associated MARCKSL1 Regulates Fibroblast Differentiation During Wound HealingWound Repair RegenMarch 4, 2026Kento Takaya, Yukari Nakajima, Shigeki Sakai, Keisuke Okabe, Noriko Aramaki-Hattori, Ryoichi Mori, Kazuo Kishiserum (FBS) and 1% penicillin–streptomycin. Cells were subsequently stimulated with 5 ng/mL TGF‐β1 (7666‐MB‐005, R&D Systems, Minneapolis, MN, USA) for 24 h. Following stimulation, DCs were washed thrice with phosphate‐buffered

(3) Deficiency of exocyst complex component Exoc5 exacerbates the progression of kidney fibrosisExperimental & Molecular MedicineMarch 4, 2026Hui Jae Lim, Yong Kwon Han, Mi Ra Noh, You Ri Park, Se Young Jang, Joshua H. Lipschutz, Kwon Moo ParkThe cell culture medium was changed to DMEM/F12 and further incubated with 5 ng/ml TGF-β (cat. no. 7666-MB-005, R&D Systems) or vehicle for 1 and 48 h. Statistics All data were analyzed using Graphpad Prism 9

(4) Cryptococcus neoformans responds to presence of Mycobacterium by diversifying its morphologies and remodelling its capsular materialJournal of Medical MicrobiologyFebruary 23, 2026Orlando Ross, Andrew Akampurira, Liliane Mukaremera, Ivy M. Dambuza(GM-CSF) (415 ml-020, Bio-techne, Abingdon, UK) and 2 ng ml−1 Transforming growth factor-beta (TGF-β) (7666 MB-005, Bio-techne, Abingdon, UK) (hereby referred to as GT media). These cells were maintained at 37 °C, 5%

(5) Galectin7 attenuates abdominal aortic aneurysm progression by resisting disturbed flow induced endothelial-to-mesenchymal transitionTheranosticsJanuary 8, 2026Yanbing Wang, Yilin Zhou, Yeshen Zhang, Danni Tu, Guojun Chen, Yuan Han, Xiaomin Wei, Yanmei Chen, Senlin Huang, Yulin Liao, et al.IgG (BioXCell, BE0083) as a control. To induce EMT, recombinant mouse TGF-β1 protein (R&D Systems, 7666-MB-005) was administered at a dosage of 10 ng via intraperitoneal injection every other day; vehicle injection

(6) Allogeneic MHC-mismatched microglia-like cell replacement as a therapeutic approach for multiple sclerosisJournal of NeuroinflammationJanuary 8, 2026Irene Benito-Cuesta, Jin-Hong Min, Yuxi Guo, Giulia Adriana Virgilio, Valerie Suerth, Stefan Bencina, Paula Trigo-Alonso, Keying Zhu, Shin-Yu Kung, Majid Pahlevan Kakhki, et al.(R&D systems, 417-ML-005), 20ng/ml IL-4 (R&D systems, 404-ML-010) and 20ng/ml TGF-b 1 (R&D systems, 7666-MB-005) to promote an anti-inflammatory phenotype (M2). Unstimulated MLCs (M0) were maintained in complete

(7) Exosomal NAMPT from Engineered Mesenchymal Stem Cells Mitigates Aortic Stenosis via Metabolic and Anti-Inflammatory PathwaysInternational Journal of Molecular SciencesDecember 25, 2025Dipan Kumar Kundu, Matthew Kiedrowski, James Gadd, Min Gao, Madeline Evan, Yang Wang, Liya Yin, Vahagn Ohanyan, William M. Chilian, Feng DongControl (no treatment), TGF-β1 (recombinant mouse TGF-β1, 10 ng/mL, R&D Systems, Minneapolis, MN, USA, 7666-MB-005), and TGF-β1+miR-146a-3p inhibitor/miR NC5 negative control (Integrated DNA Technologies, Coralville,

(8) Dual-functional nanovesicles simultaneously inhibit stromal fibrosis and angiogenesis to suppress cholangiocarcinoma progressionJ NanobiotechnologyDecember 22, 2025Lijing Zhang, Xixi Duan, Qiying Shi, Xiaohan Yao, Qiang Chen, Jiajia Wan, Fazhan Wang, Chen Ni, Yongjuan Li, Ming Wang, et al.formulations at the aforementioned in 1% FBS medium, followed by 48 h stimulation with TGF-β (5 ng/mL; Cat. #7666-MB-005; R&D Systems). Gel contraction was monitored using stereomicroscopy, with relative diameters of wells

(9) Enhanced Glioblastoma Immunotherapy via SMAC Mimetic Dose Escalation and TGFβ BlockadeNeuro-Oncology AdvancesDecember 10, 2025Kyle Malone, Melanie Dugas, Nathalie Earl, Tommy Alain, Robert G Korneluk, Eric LaCasse, Shawn T Beugand tumor-associated immune cells. Methods Reagents TNF-α (410-MT-010), IL-1β (401-ml) and TGFβ (7666-MB-005) were purchased from R&D systems. IFNγ was purchased from R&D systems (4875-M1) or Peprotech (315-05).

(10) SMAD4 induces opposite effects on metastatic growth from pancreatic tumors depending on the organ of residenceNature CancerSeptember 25, 2025Kaloyan M. Tsanov, Francisco M. Barriga, Yu-Jui Ho, Direna Alonso-Curbelo, Geulah Livshits, Sha Tian, Richard P. Koche, Timour Baslan, Janelle Simon, Alexandra N. Wuest, et al.collagen-coated 24-well plates, in the presence or absence of 100 pM recombinant mouse TGFβ1 (R&D Systems, 7666-MB-005). Cells were counted every 3 days (that is, on days 3, 6 and 9) using a Guava easyCyte instrument (EMD

(11) Dysregulated RNA splicing impairs regeneration in alcohol-associated liver diseaseNature communicationsSeptember 10, 2025Chembazhi UV, Bangru S, Dutta RK, Das D, Peiffer B, Natua S, Toohill K, Leona A, Purwar I, Bhowmik A, et al.

(12) Mast Cell Phenotypic Heterogeneity Impacts the Interplay with Pathogenic Salmonella Typhimurium BacteriaEuropean journal of immunologyAugust 1, 2025von Beek C, Prensa GI, Andersson JHM, Pejler G, Sellin ME.

(13) A variant form of receptor activator of nuclear factor-κB functions as an osteoprotegerin mimic in bone and cardiac developmentScientific reportsJuly 31, 2025Kitazawa R, Haraguchi R, Kitazawa S.

(14) Dissecting FAP+ Cell Diversity in Pancreatic Cancer Uncovers an Interferon-Response Subtype of Cancer-Associated Fibroblasts with Tumor-Restraining PropertiesCancer researchJuly 2, 2025Cumming J, Maneshi P, Dongre M, Alsaed T, Dehghan-Nayeri MJ, Ling A, Pietras K, Patthey C, Öhlund D.media, mT CM, or splitting media with 100 ρg/mL, 1, 10, or 100 ηg/mL recombinant TGFβ (R&D Systems, 7666-MB-005). For mT CM, mTs were seeded after mechanical fragmentation. mTs were cultured for 2 days in complete

(15) Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunityNatureJuly 1, 2025Faust Akl C, Andersen BM, Li Z, Giovannoni F, Diebold M, Sanmarco LM, Kilian M, Fehrenbacher L, Pernin F, Rone JM, et al.ml−1 EGF (PeproTech, 315–09), 100 ng ml−1 TGFα (PeproTech, 100–16A), 100 ng ml−1 TGFβ (R&D Systems, 7666-MB-005), 100 ng ml−1 IL-15 (PeproTech, 210–15) and 50 ng ml−1 IFN-γ (R&D Systems, 485-MI-100). Isolation,

(16) Interactive Effects of IL-1β and TGF-β on Urokinase-Type Plasminogen Activator and α-Smooth Muscle Actin Expression by Corneal FibroblastsInvestigative ophthalmology & visual scienceJuly 1, 2025Sugioka K, Nishida T, Yunoki M, Mukai N, Murakami J, Kusaka S.induced with a microsurgical blade (Straight; Mani, Utsunomiya, Japan), and recombinant mouse TGF-β1 (7666-MB-005; R&D Systems) at 10 ng/mL or PBS was topically applied to the injured cornea every 4 hours up to 16

(17) Omaveloxolone, But Not Dimethyl Fumarate, Improves Cardiac Function in Friedreich's Ataxia Mice With Severe CardiomyopathyJournal of the American Heart AssociationJune 17, 2025Lili Salinas, Francisco Figueroa, Claire B. Montgomery, Phung N. Thai, Nipavan Chiamvimonvat, Gino Cortopassi, Elena N. Dedkovahours, then replenished with 10 ng/mL recombinant mouse TGFβ (transforming growth factor‐β; R&D Systems, 7666‐MB‐005) and maintained for 3 to 5 days before treatment with omaveloxolone and DMF. Cells were treated with

(18) CST Is Epistatic With Shieldin to Limit DNA Double-Strand Break End Resection and Promote Repair During Igh Class Switch RecombinationEuropean journal of immunologyApril 1, 2025Lescale C, Marton T, Vaysse A, Rode G, Vincendeau E, Libri A, Dossin F, Deriano L.

(19) Modulation of gut propionate and intestinal mucosal protection by Bifidobacterium longum: Mitigating methotrexate side effects without compromising the efficacy of psoriasis therapyInternational immunopharmacologyMarch 6, 2025Mao M, Yuan Y, Li R, Kuang Y, Lu Y, Zhu W, Chen W.

(20) Differential Roles of Macrophages and Microglia in Subretinal Fibrosis Secondary to Neovascular Age-Related Macular DegenerationInvestigative ophthalmology & visual scienceMarch 3, 2025Szczepan M, Llorián-Salvador M, Yi C, Hughes D, Mack M, Chen M, Xu H.

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10/7/2016Stimulation of cultured mouse cells using TGF-ß1 Sadaf AtarodThe aim of this experiment was to stimulate TGF-Beta 1 during the directed differentiation protocol & test the expression levels of a set of genes. The main reasons were the stability of the TGF-Beta ... Read Review

TGF-beta 1 Protein

TGF-beta 1 Protein

TGF-beta 1 Protein

Recombinant Mouse TGF-beta 1 Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse TGF-beta 1 Protein from R&D Systems, a Bio-Techne Brand

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