TGF-beta 1 Protein 7754-BH-005/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTGF-beta 1 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $306.00Supplier Page View Company Product Page
Catalog Number7754-BH-005/CF
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 11 kDa, reducing conditions
Theoretical: 12.8 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Gene AliasesTGF-beta1, TGFB, DPD1, TGFbeta, CED, IBDIMDE, LAP
NCBI Full Gene Nametransforming growth factor beta 1
Source/Expression SystemHEK293-derived Recombinant Human TGF-beta 1 (Human Cell-expressed), CF
SpeciesHuman
Molecule NameTGF-beta 1
Size5 ug (also 25 ug, 100 ug, 500 ug, 1000 ug)

Specifications/Features

Available conjugates: Sizes Available: 5 ug (also 25 ug, 100 ug, 500 ug, 1000 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Therapeutic manipulation and spatial quantification of the tumour microenvironment in colorectal canceriScienceApril 17, 2026Eoghan J. Mulholland-Illingworth, Joshua W. Moore, Muyang Lin, Raheleh Amirkhah, Lucile Grzesiak, Amelia Ligeza, Joshua A. Bull, Joseph Boen, Gabriel N. Valbuena, Michael A. Gillespie, et al.ML TGFβ1 recombinant mouse protein,R&D Systems,7666-MB TGFβ1 recombinant human protein,R&D Systems,7754-BH-005/CF ,, Critical commercial assays,Critical commercial assays,Critical commercial assays ,, RNeasy Micro

(2) Avidity-optimized TCR-T cells target KRAS neoantigens for potent cancer clearance and tumor microenvironment remodelingFrontiers in ImmunologyJanuary 26, 2026Zhaoduan Liang, Fengqiong Guan, Bingling Wu, Wenfang Chen, Ye Tian, Wenxuan Cai, Yi Likynurenine (InvivoChem, cat# V13205) (KHAA), or recombinant human TGF-β1 (rhTGF-β1; R&D Systems, cat# 7754-BH-005/CF). KHAA was dissolved in DMSO to 0.4 M stock and tested at 50–400 μM; DMSO concentration was matched

(3) Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombinationMolecular CellApril 3, 2025Lizhen Wu, Anurupa Devi Yadavalli, Filip Senigl, Gabriel Matos-Rodrigues, Dijin Xu, Andreas P. Pintado-Urbanc, Matthew D. Simon, Wei Wu, André Nussenzweig, David G. SchatzRecombinant Murine IL-4,Peprotech,Cat.#214-14 Recombinant Human TGF-beta 1 (Human Cell-expressed) Protein,R&D,Cat.#7754-BH-005/CF dTAGV-1,Tocris,Cat#6914 dTAGV-1-NEG,Tocris,Cat#6915 4-Thiouridine,fisherscientific,Cat#AAJ60679MC MTSEA

(4) Transcriptional signature of rapidly responding NK cells reveals S1P5 and CXCR4 as anti-tumor response disruptorsScientific reportsMarch 28, 2025Puig-Gámez M, Van Attekum M, Theis T, Dick A, Park JE.stimulated with recombinant Human IL-2 10 ng/mL (BioLegend, 589104), or inhibited with TGF-β (Bio-Techne, 7754-BH-005/CF) at the same concentration, and cells were cultured at 37 °C and 5% CO2 for 2 days. If ceralifimod (Merk,

(5) Transcription factor TCF1 binds to RORγt and orchestrates a regulatory network that determines homeostatic Th17 cell stateImmunityNovember 1, 2024Davide Mangani, Ayshwarya Subramanian, Linglin Huang, Hanning Cheng, S. Harsha Krovi, Yufan Wu, Dandan Yang, Thais G. Moreira, Giulia Escobar, Alexandra Schnell, et al.401-ML-005/CF IL-6,R&D Systems,Cat # 406-ML-005/CF IL-23,R&D Systems,Cat# 11269-ML-010 TGFb1,R&D Systems,Cat# 7754-BH-005/CF Myelin oligodendrocyte glycoprotein (MOG) peptide MOG35-55,Genemed Synthesis,Cat# MOG3555-P2-5 Complete

(6) Milk levels of transforming growth factor beta 1 identify mothers with low milk supplyPLOS ONEJune 13, 2024Rhea Sullivan, Alexandra Confair, Steven D. Hicksand gentamicin-amphotericin, according to manufacturer recommendations. TGF-β1 (R&D Systems, Cat. # 7754-BH-005/CF) was reconstituted in 0.1% bovine serum albumin in 4 mM hydrochloric acid. HMECs were cultured for 48

(7) Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell developmentNature communicationsMarch 9, 2024Kim T, Martínez-Bonet M, Wang Q, Hackert N, Sparks JA, Baglaenko Y, Koh B, Darbousset R, Laza-Briviesca R, Chen X, et al.(cell:bead), to which the indicated combination of 2 ng/mL TGF-β1 recombinant protein (R&D system, 7754BH005/CF) and 2 μg/ml anti-ICOS antibody (Invitrogen, 16-9948-82) were added for varying periods (3, 6, 10, 14,

(8) Epidermal growth factor receptor activation is essential for kidney fibrosis developmentNature communicationsNovember 14, 2023Cao S, Pan Y, Terker AS, Arroyo Ornelas JP, Wang Y, Tang J, Niu A, Kar SA, Jiang M, Luo W, et al.Sigma-Aldrich), HB-EGF plus an EGFR inhibitor (AG1478, 10 μM, LC laboratories) or TGF-β (5 ng/ml, cat# 7754BH005CF, R&D Systems™) in the presence or absence of 5% serum for 16 h. Cells in the upper chamber were removed

(9) Minoxidil weakens newly synthesized collagen in fibrotic synoviocytes from osteoarthritis patientsJ Exp OrthopAugust 21, 2023Stefan Sarkovich, Peter P. Issa, Andrew Longanecker, Davis Martin, Kaitlyn Redondo, Patrick McTernan, Jennifer Simkin, Luis Marrerocontrol. Stimulation and treatment of cultured FSCs Carrier-free, recombinant TGFβ1 (R&D Systems; #7754-BH-005/CF) was dissolved in 10 mM citric acid to a 50,000 ng/ml stock for dilution in SGM to 1, 2, or 4 ng/mL

(10) Single-cell transcriptomics reveal a hyperacute cytokine and immune checkpoint axis after cardiac arrest in patients with poor neurological outcomeMedJuly 14, 2023Tamura T, Cheng C, Chen W, Merriam LT, Athar H, Kim YH, Manandhar R, Amir Sheikh MD, Pinilla-Vera M, Varon J, et al.217-IL-005/CF Recombinant human IL-27,R&D Systems,Cat# 2526-IL-010/CF Recombinant human TGF-β1,R&D Systems,Cat# 7754-BH-005/CF Recombinant human LIGHT,R&D Systems,Cat# 664-LI-025/CF Molidustat (BAY 85-3934),Cayman Chemical,Cat#

(11) Conserved stromal-immune cell circuits secure B cell homeostasis and functionNature immunologyJuly 1, 2023Lütge M, De Martin A, Gil-Cruz C, Perez-Shibayama C, Stanossek Y, Onder L, Cheng HW, Kurz L, Cadosch N, Soneson C, et al.

(12) Poricoic acid A suppresses renal fibroblast activation and interstitial fibrosis in UUO rats via upregulating Sirt3 and promoting β-catenin K49 deacetylationActa pharmacologica SinicaMay 1, 2023Chen DQ, Chen L, Guo Y, Wu XQ, Zhao TT, Zhao HL, Zhang HJ, Yan MH, Zhang GQ, Li P.

(13) Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasionThe Journal of clinical investigationApril 17, 2023Jeong YJ, Knutsdottir H, Shojaeian F, Lerner MG, Wissler MF, Henriet E, Ng T, Datta S, Navarro-Serer B, Chianchiano P, et al.(Sigma-Aldrich, PF024; 10 ng/mL), SDF-1 (CXCL12) (Peprotech, 300-28B; 100 ng/mL), and TGF-β1 (Biotechne, 7754-BH-005/CF; 5 ng/mL). The control organoids were given feeding media only. All PDAC organoids were imaged 72 hours

(14) DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell developmentCell reportsFebruary 28, 2023Mandarano AH, Harris TL, Creasy BM, Wehenkel M, Duggar M, Wilander BA, Mishra A, Crawford JC, Mullen SA, Williams KM, et al.

(15) TGF-β is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cellsArthritis research & therapyFebruary 27, 2023Klück V, Cabău G, Mies L, Bukkems F, van Emst L, Bakker R, van Caam A, HINT consortium, Crişan TO, Joosten LAB.

(16) Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitisNature communicationsFebruary 16, 2023Yang WL, Qiu W, Zhang T, Xu K, Gu ZJ, Zhou Y, Xu HJ, Yang ZZ, Shen B, Zhao YL, et al.

(17) 5-FU-miR-15a Inhibits Activation of Pancreatic Stellate Cells by Reducing YAP1 and BCL-2 Levels In VitroInternational journal of molecular sciencesFebruary 16, 2023Almanzar VMD, Shah K, LaComb JF, Mojumdar A, Patel HR, Cheung J, Tang M, Ju J, Bialkowska AB.

(18) ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulationExperimental & molecular medicineFebruary 1, 2023Cho DI, Ahn MJ, Cho HH, Cho M, Jun JH, Kang BG, Lim SY, Yoo SJ, Kim MR, Kim HS, et al.

(19) xcore: an R package for inference of gene expression regulatorsBMC bioinformaticsJanuary 11, 2023Migdał M, Arakawa T, Takizawa S, Furuno M, Suzuki H, Arner E, Winata CL, Kaczkowski B.

(20) LINC01146/F11R facilitates growth and metastasis of prostate cancer under the regulation of TGF-βThe Journal of steroid biochemistry and molecular biologyJanuary 1, 2023Guo X, Gu Y, Guo C, Pei L, Hao C.

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TGF-beta 1 Protein

TGF-beta 1 Protein

TGF-beta 1 Protein

TGF-beta 1 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (65)

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TGF-beta 1 Protein from R&D Systems, a Bio-Techne Brand

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