Z-YVAD-FMK, Irreversible caspase-1 inhibitor ab141388 from Abcam

Product Specs
ItemZ-YVAD-FMK, Irreversible caspase-1 inhibitor
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab141388
Size1 mg, 5 mg
TypeInhibitor, inhibitor
Molecule NameZ-YVAD-FMK, Irreversible caspase-1 inhibitor

Sequence

YVAD

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Impact of surface functional group modification on cellular internalization and cytotoxicity of silica nanoparticlesParticle and Fibre ToxicologyDecember 19, 2025Sandra Vranic, Eri Watanabe, Kyoka Yamazaki, Takatsugu Wakahara, Kayoko Miyakawa, Sakie Takeuchi, Yurika Osada, Sahoko Ichihara, Wenting Wu, Cai Zong, et al.(#S864201, Sellekchem, Houston, TX, USA), pyroptosis inhibitor (caspase-1 and -4 inhibitor) Z-YVAD-FMK (#ab141388, Abcam, Cambridge, UK) and autophagy inhibitor (inhibitor of autophagosome-lysosome fusion) chloroquine

(2) PRRSV Infection Induces Gasdermin D-Driven Pyroptosis of Porcine Alveolar Macrophages through NLRP3 Inflammasome ActivationJournal of virologyJuly 27, 2022He S, Li L, Chen H, Hu X, Wang W, Zhang H, Wei R, Zhang X, Chen Y, Liu X.latrunculin A (M6896), and paclitaxel (M1970) were obtained from Abmole (Houston, TX). Z-YVAD-FMK (ab141388) and phalloidin fluorescein isothiocyanate (FITC) reagent (ab235137) were obtained from Abcam. 7-Actinomycin D

(3) NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucomaMolecular neurodegenerationApril 15, 2020Chen H, Deng Y, Gan X, Li Y, Huang W, Lu L, Wei L, Su L, Luo J, Zou B, et al.antibody (#14–7012-85) was obtained from eBioscience. The CASP1 inhibitor (CASP1 inh) Z-YVAD-FMK (YVAD, #ab141388) was obtained from Abcam. The NF-kB P65 inhibitor JSH-23 (#S7351) was purchased from Selleckchem. Anti-β-actin

(4) Benzene metabolites trigger pyroptosis and contribute to haematotoxicity via TET2 directly regulating the Aim2/Casp1 pathwayEBioMedicineSeptember 1, 2019Xiaoli Guo, Wen Zhong, Yujiao Chen, Wei Zhang, Jing Ren, Ai GaoAssay Kit was purchased from ImmunoChemistry Technologies (USA)., Irreversible caspase-1inhibitor (ab141388) was purchased from Abcam (UK). RevertAid First Strand cDNA Synthesis Kit was obtained from ThermoFisher Scientific

(5) Cell Death Is Counteracted by Mitophagy in HIV-Productively Infected Astrocytes but Is Promoted by Inflammasome Activation Among Non-productively Infected CellsFrontiers in immunologyJanuary 1, 2018Ojeda DS, Grasso D, Urquiza J, Till A, Vaccaro MI, Quarleri J.the mitochondria, and (ii) 48 h treatment with a caspase-1 inhibitor (50 μM, Z-YVAD-FMK, Abcam, cat#ab141388). Evaluation of cell-to-cell contact as condition for bystander effects In order to evaluate the ability

(6) Mammalian target of rapamycin inhibition counterbalances the inflammatory status of immune cells in patients with chronic granulomatous diseaseThe Journal of allergy and clinical immunologyMay 1, 2017Gabrion A, Hmitou I, Moshous D, Neven B, Lefèvre-Utile A, Diana JS, Suarez F, Picard C, Blanche S, Fischer A, et al.

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Z-YVAD-FMK, Irreversible caspase-1 inhibitor from Abcam

Sequence

Abcam

Citations (6)

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Z-YVAD-FMK, Irreversible caspase-1 inhibitor from Abcam

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