Recombinant Mouse Galectin-9 Protein, CF 3535-GA-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse Galectin-9 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $454.00Supplier Page View Company Product Page
Catalog Number3535-GA-050
Size50 ug
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in MOPS, NaCl, EDTA, DTT and Trehalose
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 36 kDa, reducing conditions
Theoretical: 36.4 kDa
Conjugate/TagUnconjugated
Molecule NameGalectin-9
SpeciesMouse
Source/Expression SystemE. coli-derived Recombinant Mouse Galectin-9 Protein, CF
NCBI Full Gene Namelectin, galactose binding, soluble 9
NCBI Gene AliasesLGALS35, gal-9, galectin-9, Lgals5
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Galectin-9high Neutrophils Exacerbate Radiation-Induced FrailtyAging CellApril 7, 2026Zhuo Cheng, Le Ma, Yan Chen, Jialun Li, Yali Dai, Wentao Xie, Yingjie Li, Tianlang Xu, Zhihe Hu, Weilin Huang, et al.Intraperitoneal injection (i.p.) of the following drugs: recombinant mouse GAL‐9 (rmGAL‐9) protein (200 μg, R&D Systems #3535‐GA‐050), anti‐GAL‐9 antibody (1 mg, BioXCell#BE0218), or IgG isotype control (1 mg, Abcam #ab172730). C57BL/6J

(2) Galectin-9 binding to HLA-DR in dendritic cells controls immune synapse formation and T cell proliferationProc Natl Acad Sci U S ADecember 16, 2025Andrea Rodgers-Furones, Thijs Brands, Guusje van Gameren, Mirane Florencio-Zabaleta, Mayukha Bathini, Sandra Delgado, Zacharias Wijfjes, Kristina Fedorova, René Classens, Lona Kroese, et al.necessary, galectin-9−/− DCs were incubated with 2 µg/ml mouse recombinant galectin-9 protein (R&D systems, #3535-GA-050) for 1 h prior to being cocultured with T cells. ELISA. Enzyme-linked immunosorbent assay kits (Invitrogen,

(3) Galectin-9 Mediates the Functions of Microglia in the Hypoxic Brain Tumor MicroenvironmentCancer researchNovember 15, 2024Lee C, Yu D, Kim HS, Kim KS, Chang CY, Yoon HJ, Won SB, Kim DY, Goh EA, Lee YS, et al.

(4) Modulation of galectin-9 mediated responses in monocytes and T-cells by pregnancy-specific glycoprotein 1The Journal of biological chemistrySeptember 1, 2024Mendoza M, Ballesteros A, Rendon-Correa E, Tonk R, Warren J, Snow AL, Stowell SR, Blois SM, Dveksler G.

(5) Effect of exogenous galectin-9, a natural TIM-3 ligand, on the severity of TNBS- and DSS-induced colitis in miceInternational immunopharmacologyFebruary 1, 2023Xiong H, Xue G, Zhang Y, Wu S, Zhao Q, Zhao R, Zhou N, Xie Y.

(6) Inhibition of Melanoma Cell-Intrinsic Tim-3 Stimulates MAPK-Dependent TumorigenesisCancer researchOctober 17, 2022Schatton T, Itoh Y, Martins C, Rasbach E, Singh P, Silva M, Mucciarone K, Heppt MV, Geddes-Sweeney J, Stewart K, et al.and Galectin-9 protein expression and binding of recombinant soluble murine Galectin-9 (R&D Systems, 3535-GA-050) by established melanoma lines and/or immune cell positive controls were analyzed by flow cytometry,

(7) Galectin-9 regulates the threshold of B cell activation and autoimmunityeLifeAugust 9, 2021Smith LK, Fawaz K, Treanor B.UT41 Antibody,Anti-C3,BioLegend,Cat#: 518106,Clone: K13/16 Recombinant Proteins,Recombinant Galectin-9,R&D Systems,Cat#: 3535-GA-050, Chemical compound/drug,Calf Thymus DNA,ThermoFisher Scientific,Cat#: 15633019, Chemical compound/drug,Phosphorylcholine,Sigma Aldrich

(8) The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptakeImmunityJune 8, 2021de Mingo Pulido Á, Hänggi K, Celias DP, Gardner A, Li J, Batista-Bittencourt B, Mohamed E, Trillo-Tinoco J, Osunmakinde O, Peña R, et al.420601 Monensin (1000x solution),BioLegend,Cat# 420701 Recombinant mouse galectin-9,R&D Systems,Cat# 3535-GA-050 Recombinant mouse TIM-3-Fc,R&D Systems,Cat# 1529-TM-050 D-Lactose monohydrate,Sigma-Aldrich,Cat# 61339 Diphtheria

(9) Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreasNature communicationsAugust 27, 2020Sudhakar JN, Lu HH, Chiang HY, Suen CS, Hwang MJ, Wu SY, Shen CN, Chang YM, Li FA, Liu FT, et al.

(10) Gangliosides modulate insulin secretion by pancreatic beta cells under glucose stressGlycobiologyAugust 20, 2020Jennemann R, Kaden S, Volz M, Nordström V, Herzer S, Sandhoff R, Gröne HJ.discarded and each plate incubated in the presence or absence of 100 mM lactose with mouse galectin-9 (3535-GA-050, R&D Systems) at a dilution of 1 µg/mL in 1% BSA in PBS overnight at 4◦ C. The plates were washed five

(11) Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibodyOncoimmunologyJanuary 1, 2020Zhang D, Jiang F, Zaynagetdinov R, Huang H, Sood VD, Wang H, Zhao X, Jenkins MH, Ji Q, Wang Y, et al.of Gal-9 to TIM-3, recombinant human Gal-9 (R&D Systems, 2045-GA-050) or murine Gal-9 (R&D Systems, 3535-GA-050) were diluted to 1 μg/mL and coated on ELISA plates and incubated overnight at 4°C. Plates were washed

(12) Possible therapeutic applicability of galectin-9 in cutaneous T-cell lymphomaJournal of dermatological scienceDecember 1, 2019Nakajima R, Miyagaki T, Kamijo H, Oka T, Shishido-Takahashi N, Suga H, Sugaya M, Sato S.

(13) N-Linked Glycosylation Regulates CD22 Organization and FunctionFrontiers in immunologyJanuary 1, 2019Wasim L, Buhari FHM, Yoganathan M, Sicard T, Ereño-Orbea J, Julien JP, Treanor B.

(14) Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA AxisThe American journal of pathologyMay 1, 2018Liang CC, Li CS, Weng IC, Chen HY, Lu HH, Huang CC, Liu FT.

(15) Dietary, nondigestible oligosaccharides and Bifidobacterium breve M-16V suppress allergic inflammation in intestine via targeting dendritic cell maturationJournal of leukocyte biologyJuly 1, 2017de Kivit S, Kostadinova AI, Kerperien J, Morgan ME, Muruzabal VA, Hofman GA, Knippels LMJ, Kraneveld AD, Garssen J, Willemsen LEM.

(16) Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune toleranceNature medicineMay 1, 2017Daley D, Mani VR, Mohan N, Akkad N, Ochi A, Heindel DW, Lee KB, Zambirinis CP, Pandian GSB, Savadkar S, et al.

(17) Alarmin function of galectin-9 in murine respiratory tularemiaPloS oneJanuary 1, 2015Steichen AL, Simonson TJ, Salmon SL, Metzger DW, Mishra BB, Sharma J.

(18) Astrocyte galectin-9 potentiates microglial TNF secretionJournal of neuroinflammationAugust 27, 2014Steelman AJ, Li J.

(19) Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparationsStem cells and developmentApril 1, 2014Ungerer C, Quade-Lyssy P, Radeke HH, Henschler R, Königs C, Köhl U, Seifried E, Schüttrumpf J.

(20) TIM-3 does not act as a receptor for galectin-9PLoS pathogensMarch 1, 2013Leitner J, Rieger A, Pickl WF, Zlabinger G, Grabmeier-Pfistershammer K, Steinberger P.

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Recombinant Mouse Galectin-9 Protein, CF

Galectin-9 Protein

Galectin-9 Protein

Recombinant Mouse Galectin-9 Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse Galectin-9 Protein, CF from R&D Systems, a Bio-Techne Brand

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