Fig 1: MiR-130b-3p was upregulatedTSC1 was downregulated in CG, mi IM and mo/se IM patients. GC, mi IM, mo/se IM patients were divided into H. pylori-positive patients and H. pylori-negative patients.(A–H) RT-qPCR detected the expression of miR-130b-3p, TSC1, SLFN12L, Shh, Smo, Gli1, VIL1, and MUC2 in gastrointestinal mucosal samples.(I–S) Western blotting assessed the expression of p-JAK2, JAK2, p-STAT1, STAT1, TSC1, SLFN12L, Shh, Smo, Gli1, VIL1, and MUC2 in gastrointestinal mucosal samples.(T–V) Immunohistochemistry examined the expression of TSC1 and VIL1 in gastrointestinal mucosal samples. Data are shown as mean ± SD. Student’s t tests were used for comparing two variables. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. H. p-/H. p+ group.